2,6-DICHLOROPHENYLBORONIC ACID
- Product Name
- 2,6-DICHLOROPHENYLBORONIC ACID
- CAS No.
- 73852-17-2
- Chemical Name
- 2,6-DICHLOROPHENYLBORONIC ACID
- Synonyms
- AKOS BRN-0086;RARECHEM AH PB 0089;2,6-DICHLOROPHENYLBO;2,6-Dichlorophenylboronic;3,6-DICHLOROPHENYLBORONICACID;2,6-Dichlorobenzeneboronicaci;2,6-DICHLOROPHENYLBORONIC ACID;2,6-DICHLOROBENZENEBORONIC ACID;2,6-Dichlorophenylboronic acid,98%;B-(2,6-Dichlorophenyl)boronic acid
- CBNumber
- CB1435113
- Molecular Formula
- C6H5BCl2O2
- Formula Weight
- 190.82
- MOL File
- 73852-17-2.mol
2,6-DICHLOROPHENYLBORONIC ACID Property
- Melting point:
- 153 °C
- Boiling point:
- 341.8±52.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Powder
- pka
- 7.94±0.58(Predicted)
- color
- Off-white
- Water Solubility
- Insoluble in water.
- BRN
- 4802506
- CAS DataBase Reference
- 73852-17-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22-36
- Safety Statements
- 26-36-37/39
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D3357
- Product name
- 2,6-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $34
- Updated
- 2025/07/31
- Product number
- D3357
- Product name
- 2,6-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $133
- Updated
- 2025/07/31
- Product number
- D473898
- Product name
- 2,6-Dichlorophenylboronicacid
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- D473898
- Product name
- 2,6-Dichlorophenylboronicacid
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD121604
- Product name
- (2,6-Dichlorophenyl)boronic acid
- Packaging
- 10g
- Price
- $70
- Updated
- 2021/12/16
2,6-DICHLOROPHENYLBORONIC ACID Chemical Properties,Usage,Production
Chemical Properties
Off-white Cryst
Uses
suzuki reaction
Uses
Reagent used for palladium-catalyzed stille and suzuki-miyaura cross-couplings, palladium (pd)-catalytized reactions. Reagent used in preparation of common building blocks for pharmaceuticals and agrochemicals.
Synthesis
688-74-4
541-73-1
73852-17-2
(1) Lithiation reaction: Add 50 g of 1,3-dichlorobenzene to a 1000 mL three-necked flask under nitrogen atmosphere and cool to -80 to -60°C. Slowly add 176 mL of n-butyl lithium (n-BuLi) dropwise. Slowly add 176 mL of n-Butyl lithium (n-BuLi) dropwise and keep the reaction temperature between -80 and -50℃. After the dropwise addition, the reaction was continued for 2 hours. (2) Lithium-hydrogen exchange reaction: 117 g of tributyl borate (B(OBu)3) was added dropwise to the phenyl lithium solution prepared above, and the reaction temperature was maintained at a holding temperature after the dropwise addition was completed. At the end of the reaction, 10% hydrochloric acid solution was added to the system for acidification, stirred and left to stratify. The organic layers were separated, combined and the solvent was removed, and treated with hydrated succinamide to obtain 51.7 g of crude 2,6-dichlorophenylboronic acid in 80% yield. (3) Purification step: 51.7 g of crude 2,6-dichlorophenylboronic acid was placed in a 1 L three-necked flask and dissolved by adding 200 mL of methyl tert-butyl ether (MTBE). After removing the solvent, cooled and crystallized, centrifuged to obtain 48.4 g of pure 2,6-dichlorophenylboronic acid in 75% yield.
References
[1] Patent: CN108084217, 2018, A. Location in patent: Paragraph 0006; 0017-0020; 0022-0024; 0026-0028; 0030-0032
2,6-DICHLOROPHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-DICHLOROPHENYLBORONIC ACID Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
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- Europe
- ProdList
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View Lastest Price from 2,6-DICHLOROPHENYLBORONIC ACID manufacturers
- Product
- 2,6-DICHLOROPHENYLBORONIC ACID 73852-17-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2,6-DICHLOROPHENYLBORONIC ACID 73852-17-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 2,6-DICHLOROPHENYLBORONIC ACID 73852-17-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-100%
- Supply Ability
- 1
- Release date
- 2018-08-12