DIPPA HYDROCHLORIDE

Product Name: DIPPA HYDROCHLORIDE
CAS No.: 155512-52-0
Chemical Name: DIPPA HYDROCHLORIDE
Synonyms: DIPPA HYDROCHLORIDE;(S)-DIPPA HYDROCHLORIDE;(S)-DIPPA hydrochloride in methanol;2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE;2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride;2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride;2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
CBNumber: CB1449770
Molecular Formula: C22H24Cl3N3OS
Formula Weight: 484.86
MOL File: Mol file

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DIPPA HYDROCHLORIDE Property

storage temp.: 2-8°C
solubility: DMSO: 26 mg/mL
form: solid
color: off-white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0794
Product name: DIPPAhydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $170
Updated: 2021/12/16

Tocris

Product number: 0794
Product name: DIPPAhydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $710
Updated: 2021/12/16

TRC

Product number: D492350
Product name: DIPPAHydrochloride
Packaging: 100mg
Price: $1210
Updated: 2021/12/16

Usbiological

Product number: 255154
Product name: DIPPA hydrochloride
Packaging: 10mg
Price: $418
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0107399
Product name: DIPPA HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $697.34
Updated: 2021/12/16

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DIPPA HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

DIPPA Hydrochloride acts as a selective antagonist to the κ-opioid receptor with a significant effect in vivo. Potential anti-depressant. Antagonist.

in vivo

DIPPA (2.5 and 5 mg/kg; s.c.) hydrochloride decreases the latency to feed in Wistar Kyoto rats, but treatment did not alter approach latencies in SD rats^[2].
DIPPA (1 and 5 mg/kg; s.c.) hydrochloride high dose increases immobility in SD rats compared to the saline-treated strain control group^[2].
DIPPA (5 mg/kg) hydrochloride decreases consumption in SD rats compared to the 5 mg/kg group of Wistar Kyoto rats. DIPPA hydrochloride significantly decreases burying time in both strains. DIPPA (5 mg/kg) hydrochloride decreases burying in both strains compared to the within strain control groups. DIPPA hydrochloride tends to decrease consumption in SD rats in the home cage but significantly increases feeding in the novel cage where potential anxiolytic-like effects of DIPPA hydrochloride may oppose the hypophagic effects of the compound^[2].

Animal Model:	Wistar Kyoto rats and SD rats (250–300 g)^[2]
Dosage:	2.5 and 5 mg/kg
Administration:	S.c.
Result:	Decreased the latency to feed in Wistar Kyoto rats, but treatment did not alter approach latencies in SD rats.

Animal Model:	Wistar Kyoto rats and SD rats (250–300 g)^[2]
Dosage:	1 and 5 mg/kg
Administration:	S.c.
Result:	High dose increased immobility in SD rats compared to the saline-treated strain control group.

IC 50

κ Opioid Receptor/KOR

storage

Desiccate at -20°C

DIPPA HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIPPA HYDROCHLORIDE Suppliers

CHINA 20 Switzerland 2 United Kingdom 1 United States 5 USA 1 Global 29

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

Tanmo Quality Inspection Technology Co., Ltd.

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 6043
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2753
Advantage: 58

R&D Systems, Inc

Tel: 18003437475
Fax: 1-612-656-4400
Email: rdname@qq.com
Country: China
ProdList: 6960
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

155512-52-0, DIPPA HYDROCHLORIDERelated Search:

DIPPA HYDROCHLORIDE

2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE

2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE

(S)-DIPPA HYDROCHLORIDE

2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride

2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride

(S)-DIPPA hydrochloride in methanol

155512-52-0

C22H23Cl2N3OSHCl

C22H23Cl2N3OSx2022HCl

Opioid receptor and opioid-like receptor