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BETA-NAADP SODIUM SALT

Product Name
BETA-NAADP SODIUM SALT
CAS No.
5502-96-5
Chemical Name
BETA-NAADP SODIUM SALT
Synonyms
NAADP;NAADP tetrasodium sa;BETA-NAADP SODIUM SALT;NAADP tetrasodium salt;Coenzyme A Impurity 15;NICOTINATE ADENINE DINUCLEOTIDE PHOSPHATE;Nicotinic acid adenine dinucleotide phosphate;nicotinic acid adenine dinucleotide*phosphate sod;NAADP (NICOTINATE ADENINE DINUCLEOTIDE P HOSPHATE);BETA-NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE
CBNumber
CB1459162
Molecular Formula
C21H28N7O17P3
Formula Weight
743.41
MOL File
5502-96-5.mol
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BETA-NAADP SODIUM SALT Property

storage temp. 
-20°C
form 
Powder
color 
White to off-white
Water Solubility 
Soluble to 50 mM in water
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N5655
Product name
Nicotinic acid adenine dinucleotide phosphate sodium salt
Purity
≥92.5%
Packaging
10mg
Price
$454.1
Updated
2025/07/31
Sigma-Aldrich
Product number
N5655
Product name
Nicotinic acid adenine dinucleotide phosphate sodium salt
Purity
≥92.5%
Packaging
25mg
Price
$949.05
Updated
2025/07/31
Tocris
Product number
3905
Product name
NAADPtetrasodiumsalt
Purity
≥98%(HPLC)
Packaging
10
Price
$325
Updated
2021/12/16
TRC
Product number
N190503
Product name
NAADPTetrasodiumSalt
Packaging
5mg
Price
$390
Updated
2021/12/16
TRC
Product number
N190503
Product name
NAADPTetrasodiumSalt
Packaging
2.5mg
Price
$235
Updated
2021/12/16
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BETA-NAADP SODIUM SALT Chemical Properties,Usage,Production

Uses

NAADP Tetrasodium Salt is a Ca2+ mobilizing agent.

Uses

Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.

General Description

NAADP induces Ca2+?release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.

Biological Activity

Ca 2+ mobilizing agent. Initiates Ca 2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca 2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca 2+ from acidic organelles.

Biochem/physiol Actions

Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.

in vivo

NAADP (0.181 mg/kg, i.v.) promotes autophagosome formation and protects the hepatocytes from injury in mice induced by LPS/GalN[3].

Animal Model:LPS/GalN induced liver injury mice model[3]
Dosage:0.181 mg/kg
Administration:i.v.
Result:Promoted autophagosome formation in in hepatocytes.
Showed higher levels of LC3II, p62, ATG5, and ATG7 in hepatocytes.

BETA-NAADP SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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BETA-NAADP SODIUM SALT Suppliers

China 27 Switzerland 1 United Kingdom 1 United States 7 USA 1 Global 37
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5502-96-5, BETA-NAADP SODIUM SALTRelated Search:

NAADP-AM NAD+ β-Nicotinamide Mononucleotide Adenine Triphosphopyridine nucleotide NADP, K BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE RESIN NADP, Disodium Salt NADP sodium salt BETA-NAADP SODIUM SALT NADP MONOPOTASSIUM SALT ALPHA-NADP SODIUM SALT β-Nicotinamide adenine dinucleotide phosphate sodium salt Nicotinic Acid Adenine Dinucleotide Phosphate

  • BETA-NAADP SODIUM SALT
  • BETA-NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE
  • NAADP tetrasodium salt
  • Nicotinicacidadeninedinucleotidephosphatetetrasodiumsalt
  • nicotinic acid adenine dinucleotide*phosphate sod
  • NAADP (NICOTINATE ADENINE DINUCLEOTIDE P HOSPHATE)
  • NICOTINIC ACID ADENINE DINUCLEOTIDE*PHOS PHATE SODIU
  • ADENOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), 2'-(DIHYDROGEN PHOSPHATE), P'(5')-3-CARBOXY-1-BETA-D-RIBOFURANOSYLPYRIDINIUM INNER SALT
  • NAADP
  • NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT
  • NICOTINATE ADENINE DINUCLEOTIDE PHOSPHATE
  • Nicotinic acid adenine dinucleotide phosphate
  • NAADP [Nicotinic acid adenine dinucleotide phosphate sodium salt]
  • Nicotinic acid adenine dinucleotide phosphate sodium salt >=92.5%
  • NAADP tetrasodium sa
  • 5'-ester with 3-carboxy-1-b-D-ribofuranosylpyridinium innersalt
  • Coenzyme A Impurity 15
  • 1,6-Dimethyl-4-(nitromethylidene)-2,2-dipropyl-3H-pyridine
  • 5502-96-5
  • C21H27N6O18P3
  • C21H23N6Na4O18P3
  • Intracellular Calcium Regulators
  • Intracellular Calcium Signaling
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical