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11-DEOXY PROSTAGLANDIN E1

Product Name
11-DEOXY PROSTAGLANDIN E1
CAS No.
37786-00-8
Chemical Name
11-DEOXY PROSTAGLANDIN E1
Synonyms
11-DEOXY PROSTAGLANDIN E1;11-deoxy Prostaglandin E1 Exclusive;9-OXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID;Prost-13-en-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-;7-((1R,2R)-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid
CBNumber
CB1459339
Molecular Formula
C20H34O4
Formula Weight
338.48
MOL File
37786-00-8.mol
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11-DEOXY PROSTAGLANDIN E1 Property

Boiling point:
509.7±35.0 °C(Predicted)
Density 
1.070±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form 
A crystalline solid
pka
4.77±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13510
Product name
11-deoxy Prostaglandin E1
Purity
≥96%
Packaging
500μg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
13510
Product name
11-deoxy Prostaglandin E1
Purity
≥96%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
13510
Product name
11-deoxy Prostaglandin E1
Purity
≥96%
Packaging
5mg
Price
$254
Updated
2024/03/01
Cayman Chemical
Product number
13510
Product name
11-deoxy Prostaglandin E1
Purity
≥96%
Packaging
10mg
Price
$443
Updated
2024/03/01
AK Scientific
Product number
1150AH
Product name
11-DeoxyprostaglandinE1
Packaging
5mg
Price
$380
Updated
2021/12/16
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11-DEOXY PROSTAGLANDIN E1 Chemical Properties,Usage,Production

Uses

11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs[1].

Definition

ChEBI: 11-deoxyprostaglandin E1 is a prostanoid.

in vivo

11-Deoxy prostaglandin E1 (administered as a spray) has no significant bronchodilator effect in guinea pigs and cats[1].

References

[1] Greenberg R, et al. The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578). Can J Physiol Pharmacol. 1975 Oct;53(5):799-809. DOI:10.1139/y75-110

11-DEOXY PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

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11-DEOXY PROSTAGLANDIN E1 Suppliers

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