15(S)-15-METHYL PROSTAGLANDIN E1
- Product Name
- 15(S)-15-METHYL PROSTAGLANDIN E1
- CAS No.
- 35700-26-6
- Chemical Name
- 15(S)-15-METHYL PROSTAGLANDIN E1
- Synonyms
- 15(S)-15-methyl PGE1;OMNFCPCBKCERJP-XBZFKEOQSA-N;15(S)-15-methyl Prostaglandin E;15(S)-15-METHYL PROSTAGLANDIN E1;15(S)-15-methyl Prostaglandin E1;9-oxo-11α,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid;9-OXO-11ALPHA,15S-DIHYDROXY-15-METHYL-PROST-13E-EN-1-OIC ACID;Prost-13-en-1-oic acid,11,15-dihydroxy-15-methyl-9-oxo-, (11a,13E,15S)- (9CI);Prost-13-en-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (11α,13E,15S)- (9CI)
- CBNumber
- CB5181863
- Molecular Formula
- C21H36O5
- Formula Weight
- 368.51
- MOL File
- 35700-26-6.mol
15(S)-15-METHYL PROSTAGLANDIN E1 Property
- Boiling point:
- 534.9±50.0 °C(Predicted)
- Density
- 1.118±0.06 g/cm3(Predicted)
- solubility
- DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
- pka
- 4.77±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 13730
- Product name
- 15(S)-15-methyl Prostaglandin E1
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $583
- Updated
- 2024/03/01
- Product number
- 13730
- Product name
- 15(S)-15-methyl Prostaglandin E1
- Packaging
- 100μg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 13730
- Product name
- 15(S)-15-methyl Prostaglandin E1
- Packaging
- 500μg
- Price
- $365
- Updated
- 2024/03/01
- Product number
- 1217AH
- Product name
- 15(S)-15-MethylprostaglandinE1
- Packaging
- 1mg
- Price
- $748
- Updated
- 2021/12/16
15(S)-15-METHYL PROSTAGLANDIN E1 Chemical Properties,Usage,Production
Description
15(S)-
Uses
15-Methylprostaglandin E1 (15S-15-Methyl-PGE1) exhibits a positiv chronotropic effect, increases the heart rate and levels of nicardipine[1].
Definition
ChEBI: 15-Methyl-15S-Prostaglandin E1 is a prostanoid.
in vivo
15-Methylprostaglandin E1 (0.01-100 nM) induces a long-lasting heart rate increases in a dose-dependent manner without alters in heart contractility in guinea pig, which is probably altered by Na+/Ca+ concentration.
| Animal Model: | guinea pigs with isolated atria[1] |
| Dosage: | 0.01-100 nM |
| Administration: | |
| Result: | Increased heart rate. |
References
1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980).
15(S)-15-METHYL PROSTAGLANDIN E1 Preparation Products And Raw materials
Raw materials
Preparation Products
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