Everolimus Hydrolized Impurity

Product Name: Everolimus Hydrolized Impurity
CAS No.: 769905-89-7
Chemical Name: Everolimus Hydrolized Impurity
Synonyms: Everolimus Impurity 37;seco Everolimus B (~90%);Everolimus Open-Ring Acid Impurity;2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoac...
CBNumber: CB14631764
Molecular Formula: C53H85NO15
Formula Weight: 976.26
MOL File: 769905-89-7.mol

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Everolimus Hydrolized Impurity Property

Melting point:: >110°C (dec.)
Boiling point:: 1010.0±75.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.24±0.20(Predicted)
color: Light Beige to Brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: E945410
Product name: secoEverolimusB(~90%)
Packaging: 5mg
Price: $3465
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 94730
Product name: secoEverolimusB
Packaging: 5mg
Price: $9100
Updated: 2021/12/16

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Everolimus Hydrolized Impurity Chemical Properties,Usage,Production

Uses

seco Everolimus B is a metabolite of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.

Everolimus Hydrolized Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Everolimus Hydrolized Impurity Suppliers

China 13 India 3 United States 1 Global 17

Shanghai Lollane Biological Technology Co.,Ltd.

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BOC Sciences

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Shanghai Haozhixiang Biotechnology Co., Ltd

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Meng Cheng Technology (Shanghai) Co., LTD

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Shandong WorldSun Biological Technology Co., Ltd.

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Energy Chemical

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Changzhou Xianglong Pharmaceutical Technology Co., LTD

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QUALITY CONTROL SOLUTIONS LTD.

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769905-89-7, Everolimus Hydrolized ImpurityRelated Search:

Everolimus 2-Piperidinecarboxylic acid, 1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-heptenyl es... 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Everolimus EP Impurity E USDOYNAPNXMXOE-SPSCNLKESA-N Everolimus Impurity 1 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Everolimus Related Compound 3 EveroliMus-d4 Everolimus Related Compound 2 Rapamycin, 32-O-demethyl- Seco Rapamycin 28-epirapamycin Everolimus Ring-Opening Impurity 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone

Everolimus Open-Ring Acid Impurity

seco Everolimus B (~90%)

Everolimus Impurity 37

2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoac...

769905-89-7