ChemicalBook > CAS DataBase List > (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Product Name
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS No.
2093243-16-2
Chemical Name
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-013-Z;Nidanibu Impurity 8;Nidanib Impurity 50;Nintedanib impurities11;(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-
CBNumber
CB14656048
Molecular Formula
C17H13NO4
Formula Weight
295.29
MOL File
2093243-16-2.mol
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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Property

Melting point:
>215°C (dec.)
Boiling point:
536.9±50.0 °C(Predicted)
Density 
1.357±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
4.50±1.00(Predicted)
color 
Yellow to Dark Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M323629
Product name
(Z)-Methyl3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Packaging
50mg
Price
$235
Updated
2021/12/16
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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production

Uses

(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate manufacturers

Moxin Chemicals
Product
Nintedanib Impurity 50 2093243-16-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
95%+
Supply Ability
100000000
Release date
2024-12-16