ChemicalBook > CAS DataBase List > HYDROQUININE

HYDROQUININE

Product Name: HYDROQUININE
CAS No.: 522-66-7
Chemical Name: HYDROQUININE
Synonyms: NSC 41799;HYDROQUININE;Quinine Impurity 5;10,11-Dihydroquinine;Hydrogenated quinine;Quinine EP Impurity C;(-)-Dihydroquinine-RM;Dihydroquinine,99%d.e.;Quinine, 10,11-dihydro-;Hydroquinine,Dihydroquinine
CBNumber: CB1473146
Molecular Formula: C20H26N2O2
Formula Weight: 326.44
MOL File: 522-66-7.mol

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HYDROQUININE Property

Melting point:: 168-176 °C(lit.)
alpha: D18 -142° (alc); D20 -236° (c = 0.82 in 0.1N H2SO4)
Boiling point:: 464.47°C (rough estimate)
Density: 1.1117 (rough estimate)
refractive index: 1.6800 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form: Solid
pka: 5.33(at 25℃)
color: White to Off-White
optical activity: [α]25/D 148°, c = 1 in ethanol
Water Solubility: 99.99mg/L(20 ºC)
Merck: 13,4832
BRN: 91444
InChIKey: LJOQGZACKSYWCH-WGFDLZGGSA-N
LogP: 3.770 (est)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 1544
WGK Germany: 3
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80965
Product name: (-)-Dihydroquinine
Purity: phyproof?ReferenceSubstance
Packaging: 100mg
Price: $231
Updated: 2025/07/31

Sigma-Aldrich

Product number: 337714
Product name: Hydroquinine
Purity: 98%
Packaging: 5g
Price: $229
Updated: 2025/07/31

TCI Chemical

Product number: D6112
Product name: (-)-Dihydroquinine
Packaging: 1G
Price: $101
Updated: 2025/07/31

TCI Chemical

Product number: D6112
Product name: (-)-Dihydroquinine
Packaging: 5G
Price: $303
Updated: 2025/07/31

TRC

Product number: D449915
Product name: (-)-Dihydroquinine
Packaging: 10g
Price: $1455
Updated: 2021/12/16

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HYDROQUININE Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

(-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.

Definition

ChEBI: Hydroquinine is a cinchona alkaloid.

Purification Methods

Hydroquinine [522-66-7] M 326.4, m 168-171o, 171.5o, [ ] D-143o (c 1.087, EtOH), 5.33 and 8.87. Recrystallise hydroquinine from EtOH, Et2O or *C6H6. [Rabe & Schultz Chem Ber 66 120 1933, Beilstein 23 III/IV 3193, 23/13 V 340.]

HYDROQUININE Preparation Products And Raw materials

Raw materials

Preparation Products

(DHQ)2PYR

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View Lastest Price from HYDROQUININE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dihydroquinine 522-66-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dihydroquinine 522-66-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: HYDROQUININE 522-66-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 500kg/month
Release date: 2019-08-01

522-66-7, HYDROQUININERelated Search:

HYDROQUININE-1,4-PHTHALAZINEDIYL DIETHER,HYDROQUININE-1,4-PHTHALOZINEDIYL DIETHER HYDROQUINIDINE (ANTHRAQUINONE-1,4-DIYL) DIETHER HYDROQUININE 1,4-PHTHALAZINEDIYL DIETHER (1S,4S)-2-OXA-5-AZABICYCLO[2.2.1]HEPTANE HCL 3-AMINO-1,2,4-DITHIAZOLE-5-THIONE HYDROQUININE HYDROBROMIDE HYDRATE HYDROQUINIDINE Quinine Hydroquinine hydrate hydrobromide HYDROQUININE ETHYLHYDROCUPREINE ETHYLHYDROCUPREINE HYDROCHLORIDE O-(9-PHENANTHRYL)HYDROQUININE,HYDROQUININE 9-PHENANTHRYL ETHER HYDROQUININE (ANTHRAQUINONE-1 4-DIYL) HYDROQUININE 2,5-DIPHENYL-4,6-PYRIMIDINEDIYL DIETHER 3,10-Dihydroxy Hydroquinine 9-Acetate,9-Acetyl-3,10-dihydroxy Hydroquinine HYDROQUININE 4-CHLOROBENZOATE,O-(4-chlorobenzoyl)hydroquinine,Dihydroquinine 4-chlorobenzoate, Hydroquinine 4-chlorobenzoate HYDROQUININE (ANTHRAQUINONE-1,4-DIYL)DIETHER

HYDROQUININE

Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8alpha,9R)-

Quinine, 10,11-dihydro-

(8S,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol

(8α,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol

(8α,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol

10,11-Dihydroquinine

Hydroquinine,Dihydroquinine

(R)-{5-ethyl-1-azabicyclo[2.2.2]octan-2-yl}(6-Methoxyquinolin-4-yl)Methanol

(1R)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-Methoxyquinolin-4-yl)Methanol

Cinchonan-9-ol, 10,11-dihydro-6'-Methoxy-, (8α,9R)-

Dihydroquinine,99%d.e.

Dihydroquinine (R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

Cinchonan-9-ol,10,11-dihydro-6'-methoxy-, (8a,9R)-

NSC 41799

Quinine Sulphate EP Impurity C

Quinine EP Impurity C

(8α,?9R)?-10,?11-Dihydro-?6'-?methoxycinchonan-?9-?ol

HYDROQUININE ISO 9001：2015 REACH

Hydrogenated quinine

Quinine Impurity 5

Hydroquinine(QuinineSulfateImpurity)

(-)-Dihydroquinine-RM

Hydroquinine, 10 mM in DMSO

Quinine sulfate dihydrate imp C (EP): (R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol (dihydroquinine)

522-66-7

Cinchona Alkaloids

Privileged Ligands

Chiral Catalysts, Ligands, and Reagents

Asymmetric Synthesis