Cesium sulfate Property

Melting point:

1019 °C (lit.)

Boiling point:

1900 °C

Density 

4.243 g/mL at 25 °C (lit.)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

H₂O: 2 M at 20 °C, clear, colorless

form 

Powder

Specific Gravity

4.243

color 

White

PH

5.8～6.8 (50g/L, 25℃)

PH Range

6.0 - 7.5

Water Solubility 

Very soluble in water. Slightly soluble in alcohol, acetone, pyridine.

Sensitive 

Hygroscopic

Merck 

14,2016

Stability:

Stable.

InChIKey

FLJPGEWQYJVDPF-UHFFFAOYSA-L

CAS DataBase Reference

10294-54-9(CAS DataBase Reference)

NIST Chemistry Reference

Cesium sulfate(10294-54-9)

EPA Substance Registry System

Sulfuric acid, dicesium salt (10294-54-9)

Safety

Hazard Codes 

Xn

Risk Statements 

20/21

Safety Statements 

22-24/25

WGK Germany 

2

RTECS 

FL0800000

TSCA 

Yes

HS Code 

28332990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P403Store in a well-ventilated place.

Cesium sulfate Chemical Properties,Usage,Production

Description

Cesium sulfate is used for equilibrium density gradient centrifugation, one of the most useful tools for fractionation and characterization of macromolecules, such as DNA. Cesium sulfate can be used as catalyst, e.g.  catalyst of cesium sulfate/vanadium pentoxide is used in abiabatic multibed reactors to lower inlet temperature and catalyst cesium sulfate/zeolite is used in a pilot plant scale process to synthesize 4-methyl thiazol.

References

[1] Waclaw Szybalski, Use of cesium sulfate for equilibrium density gradient centrifugation, Methods in Enzymology, 1968, vol. 12, 330-360.
[2] Dmitry Yu. Murzin, Chemical Reaction Technology, 2015.
[3] James A. Schwarz, Cristian I. Contescu and Karol Putyera, Dekker Encyclopedia of Nanoscience and Nanotechnology, Volume 1, 2004.
[4] D W Kufe , P P Major , D Munroe , M Egan , D Herrick, Relationship between incorporation of 9-beta-D-arabinofuranosyladenine in L 1210 DNA and cytotoxicity, 1983.
[5] Le, F.K., Schneeweiss, P., Rauschenbeutel, A., Dynamical polarizability of atoms in arbitrary light fields: general theory and application to cesium. Eur. Phys. J. D. 2013, 67, 92.
[6] Xiufeng Zhang, Zhifeng Qin, Tahani Aldahri, Sohrab Rohani, Shan Ren, Weizao Liu, Separation and recovery of cesium sulfate from the leach solution obtained in the sulfuric acid baking process of lepidolite concentrate, 2021, 105537.

Chemical Properties

white or colourless odourless crystals

Uses

Cesium sulfate is used to prepare dense aqueous solutions for use in isopycnic centrifugation. It is also used for crystal growing purposes.

Uses

Cesium sulfate is the basic raw material for the preparation of various cesium salts, and can be used in trace analysis of aluminum and berkelium analysis reagent. It is often used as a liquid medium for density gradient centrifugation to separate and extract nucleic acids, suborganelles and plasmids ^[4].

Uses

With V or V2O5 as catalyst for SO2 oxidation.

Preparation

Lepidolite is an important mineral resource for the preparation of lithium, rubidium and cesium^[5]. And cesium can be collected from the leaching solution by the process of crystallization, roasting, dissolution and solvent extraction. After the leaching solution is cooled from 85 °C to 35 °C. The mixture is calcined at 900 °C after most of Cs⁺ is precipitated as CsAl(SO₄)₂.XH₂O, and the calcined product is dissolved in water to obtain Cs⁺ mixed sulfuric acid solution^[6]. After four-stage countercurrent extraction, obtain the mixed sulfuric acid solutionis. Cs⁺ (99.20%) was extracted and purified by 4-tert-butyl-2-(α-methylbenzyl) phenol (t-BAMBP). The organic phase dissolved with CS⁺ was scrubbing and stripped with sulfuric acid, and cesium sulfate products were obtained after crystallization.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise it from water (0.5mL/g) by adding ethanol and cooling.