ChemicalBook > CAS DataBase List > (S)-4-Hydroxy-2-pyrrolidinone

(S)-4-Hydroxy-2-pyrrolidinone

Product Name
(S)-4-Hydroxy-2-pyrrolidinone
CAS No.
68108-18-9
Chemical Name
(S)-4-Hydroxy-2-pyrrolidinone
Synonyms
SHPD;OxiracetaM iMpurity A;Oxiracetam Impurity 9;Oxiracetam impurity H;Oxiracetam Impurity N;Busulfan Impurity1706;Oxiracetam impurities1718;4-HYDROXY-PYRROLIDIN-2-ONE;(S)-4-HYDROXY-2-PYRROLIDONE;(s)-β-hydroxy-γ-butyrolactam
CBNumber
CB1474345
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
68108-18-9.mol
More
Less

(S)-4-Hydroxy-2-pyrrolidinone Property

Melting point:
156-159 °C (lit.)
alpha 
-41 º (c=% in ethanol)
Boiling point:
363.6±35.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Water Solubility 
Slightly soluble in water
pka
13.62±0.20(Predicted)
form 
Solid
color 
White to off-white
optical activity
[α]23/D 43°, c = 1 in ethanol
BRN 
1524192
InChIKey
IOGISYQVOGVIEU-VKHMYHEASA-N
CAS DataBase Reference
68108-18-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
479179
Product name
(S)-(?)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
5g
Price
$94
Updated
2024/03/01
Sigma-Aldrich
Product number
479179
Product name
(S)-(?)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
1g
Price
$52.5
Updated
2023/06/20
TCI Chemical
Product number
H1368
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidone
Purity
>98.0%(GC)
Packaging
1g
Price
$205
Updated
2024/03/01
Alfa Aesar
Product number
H66455
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
250mg
Price
$36.7
Updated
2023/06/20
Alfa Aesar
Product number
H66455
Product name
(S)-(-)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
1g
Price
$106
Updated
2023/06/20
More
Less

(S)-4-Hydroxy-2-pyrrolidinone Chemical Properties,Usage,Production

Chemical Properties

White crystal

Uses

(S)-(?)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:

  • Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
  • Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.

Uses

The (S)-enantiomer intermediate in the preparation of Oxiracetam

General Description

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.

(S)-4-Hydroxy-2-pyrrolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-4-Hydroxy-2-pyrrolidinone Suppliers

Americas 1 Canada 2 China 182 Europe 1 France 1 Germany 5 India 13 Japan 4 South Korea 3 Switzerland 2 United Kingdom 14 United States 44 Global 272
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7195
Advantage
65
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1637
Advantage
59
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9458
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Doly Chemical CO.,LTD.
Tel
021-34716221 15800796336
Fax
+86-21-31329566
Email
sales@dolypharm.com
Country
China
ProdList
294
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
028-85122536 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
Country
China
ProdList
2001
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shijiazhuang Lickon PharmaTech Co., Ltd.
Tel
031185291771 13832391721
Fax
0311-67305698
Email
yaofeng2005@163.com
Country
China
ProdList
975
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2677
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Country
China
ProdList
4987
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Shanghai Mayzem Pharmtech Co., Ltd.
Tel
18501708306
Fax
021-68362870
Email
sales@mayzem.com
Country
China
ProdList
520
Advantage
56
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
More
Less

View Lastest Price from (S)-4-Hydroxy-2-pyrrolidinone manufacturers

R&D Scientific Inc.
Product
4-Hydroxy-2-pyrrolidone 68108-18-9
Price
US $2800.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-05-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
(S)-4-Hydroxy-2-pyrrolidinone 68108-18-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
(S)-4-Hydroxy-2-pyrrolidinone 68108-18-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

68108-18-9, (S)-4-Hydroxy-2-pyrrolidinoneRelated Search:

N-Vinyl-2-pyrrolidone CHLOROPHOSPHONAZO III Polyvinylpyrrolidone 2-Pyrrolidinone N-Methyl-2-pyrrolidone Povidone iodine 4-hydroxypyrrolidin-2-one OxiracetaM Related CoMpound 2 Oxiracetam Related Compound 7 Oxiracetam 2-(2-oxo-2,5-dihydro-1H-pyrrol-1-yl)acetaMide Oxiracetam Related Compound 8 methyl 4-hydroxy-2-oxopyrrolidine-1-acetate 2-[(carbamoylmethyl)amino]acetamide Oxiracetam Related Compound 5 4-Hydroxy-2-oxo-1-pyrrolidineacetic acid (4S)-4-hydroxy-2-oxo-1-Pyrrolidineacetic acid Methyl ester ethyl 4-hydroxy-2-oxopyrrolidine-1-acetate

  • 2-PYRROLIDINONE, 4-HYDROXY-, (S)
  • 2-PYRROLIDINONE, 4-HYDROXY-, (4S)-
  • (4S)-4-HYDROXYPYRROLIDIN-2-ONE
  • 4-HYDROXY-PYRROLIDIN-2-ONE
  • (s)-(-)-β-hydroxy-γ-butyrolactam
  • (s)-β-hydroxy-γ-butyrolactam
  • (S)-(-)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-(+)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-4-HYDROXY-2-PYRROLIDINONE
  • (S)-4-HYDROXY-2-PYRROLIDONE
  • (S)-4-HYDROXY-PYRROLIDINE-2-ONE
  • SHPD
  • (S)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
  • (S)-(-)-4-Hydroxy-2-pyrrolinone
  • (4S)-4-hydroxy-2-pyrrolidone
  • (S)-4-Hydroxy-pyrrolidin-2-one
  • (4S)-(-)-4-Hydroxy-2-oxopyrrolidine, (4S)-(-)-beta-Hydroxy-gamma-butyrolactam
  • (4S)-4-Hydroxy-2-pyrrolidinone
  • OxiracetaM iMpurity A
  • Oxiracetam Impurity 9
  • (S)-4-Mercapto-2-pyrrolidone
  • Oxiracetam Impurity A ((S)-4-Hydroxy-2-pyrrolidinone)
  • (S)-(-)-4-Hydroxy-2-pyrrolidinone 97%
  • (S)-4-Hydroxy-2-pyrrolidone,99%e.e.
  • Oxiracetam impurity H
  • Oxiracetam Impurity N
  • (S)-(-)-4-Hydroxy-2-pyrrolidone&gt
  • Busulfan Impurity1706
  • Oxiracetam impurities1718
  • (S)-(-)-4-Hydroxy-2-pyrrolidinone (Oxiracetam Impurity)
  • 68108-18-9
  • C4H7NO2
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral
  • Pyrrolidinone derivatives
  • Drug Intermediates