H-GLY-PRO-GLY-NH2 HCL
- Product Name
- H-GLY-PRO-GLY-NH2 HCL
- CAS No.
- 141497-12-3
- Chemical Name
- H-GLY-PRO-GLY-NH2 HCL
- Synonyms
- GPG-NH2;H-Gly-Pro-Gly-NH2;H-GLY-PRO-GLY-NH2 HCL;Glycyl-L-prolylglycinamide;Glycinamide, glycyl-L-prolyl-;H-Gly-Pro-Gly-NH2 hydrochloride
- CBNumber
- CB1483048
- Molecular Formula
- C9H16N4O3
- Formula Weight
- 228.25
- MOL File
- 141497-12-3.mol
H-GLY-PRO-GLY-NH2 HCL Property
- Boiling point:
- 618.0±55.0 °C(Predicted)
- Density
- 1.326±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 14.27±0.20(Predicted)
- Sequence
- H-Gly-Pro-Gly-NH2 · HCl
N-Bromosuccinimide Price
- Product number
- PEP0001494
- Product name
- GLY-PRO-GLY-NH2 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $757.97
- Updated
- 2021/12/16
H-GLY-PRO-GLY-NH2 HCL Chemical Properties,Usage,Production
Uses
H-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 IIIB and HIV-2 ROD with EC50 values of 35 μM and 30 μM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research[1][2][3].
IC 50
HIV (IIIB): 35 μM (EC50); HIV-2 (ROD): 30 μM (EC50)
References
[1] H?glund S, et al. Tripeptide interference with human immunodeficiency virus type 1 morphogenesis. Antimicrob Agents Chemother. 2002 Nov;46(11):3597-605. DOI:10.1128/AAC.46.11.3597-3605.2002
[2] Andersson E, et al. No cross-resistance or selection of HIV-1 resistant mutants in vitro to the antiretroviral tripeptide glycyl-prolyl-glycine-amide[J]. Antiviral research, 2004, 61(2): 119-124.
[3] Balzarini J, et al. Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)). Int J Biochem Cell Biol. 2004 Sep;36(9):1848-59. DOI:10.1016/j.biocel.2004.02.017
H-GLY-PRO-GLY-NH2 HCL Preparation Products And Raw materials
Raw materials
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