ChemicalBook > CAS DataBase List > H-GLY-PRO-GLY-NH2 HCL

H-GLY-PRO-GLY-NH2 HCL

Product Name
H-GLY-PRO-GLY-NH2 HCL
CAS No.
141497-12-3
Chemical Name
H-GLY-PRO-GLY-NH2 HCL
Synonyms
GPG-NH2;H-Gly-Pro-Gly-NH2;H-GLY-PRO-GLY-NH2 HCL;Glycyl-L-prolylglycinamide;Glycinamide, glycyl-L-prolyl-;H-Gly-Pro-Gly-NH2 hydrochloride
CBNumber
CB1483048
Molecular Formula
C9H16N4O3
Formula Weight
228.25
MOL File
141497-12-3.mol
More
Less

H-GLY-PRO-GLY-NH2 HCL Property

Boiling point:
618.0±55.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
14.27±0.20(Predicted)
Sequence
H-Gly-Pro-Gly-NH2 · HCl
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0001494
Product name
GLY-PRO-GLY-NH2 HYDROCHLORIDE
Purity
95.00%
Packaging
1MG
Price
$757.97
Updated
2021/12/16
More
Less

H-GLY-PRO-GLY-NH2 HCL Chemical Properties,Usage,Production

Uses

H-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 IIIB and HIV-2 ROD with EC50 values of 35 μM and 30 μM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research[1][2][3].

IC 50

HIV (IIIB): 35 μM (EC50); HIV-2 (ROD): 30 μM (EC50)

References

[1] H?glund S, et al. Tripeptide interference with human immunodeficiency virus type 1 morphogenesis. Antimicrob Agents Chemother. 2002 Nov;46(11):3597-605. DOI:10.1128/AAC.46.11.3597-3605.2002
[2] Andersson E, et al. No cross-resistance or selection of HIV-1 resistant mutants in vitro to the antiretroviral tripeptide glycyl-prolyl-glycine-amide[J]. Antiviral research, 2004, 61(2): 119-124.
[3] Balzarini J, et al. Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)). Int J Biochem Cell Biol. 2004 Sep;36(9):1848-59. DOI:10.1016/j.biocel.2004.02.017

H-GLY-PRO-GLY-NH2 HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

H-GLY-PRO-GLY-NH2 HCL Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58