Fmoc-NMe-PEG4-acid
- Product Name
- Fmoc-NMe-PEG4-acid
- CAS No.
- 2170240-98-7
- Chemical Name
- Fmoc-NMe-PEG4-acid
- Synonyms
- Fmoc-NMe-PEG4-acid;Fmoc-NMe-PEG4-C2-acid;Fmoc-MeN-PEG4-CH2CH2COOH;Fmoc-NMe-PEG4-CH2CH2COOH;Fmoc-NMe-PEG4-acid USP/EP/BP;Fmoc-NMe-PEG4-propionic acid;2-Fmoc-5,8,11,14-tetraoxa-2-azaheptadecan-17-oic Acid;5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 2-methyl-, 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB14849594
- Molecular Formula
- C27H35NO8
- Formula Weight
- 501.57
- MOL File
- 2170240-98-7.mol
Fmoc-NMe-PEG4-acid Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23882
- Product name
- Fmoc-NMe-PEG4-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23882
- Product name
- Fmoc-NMe-PEG4-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-23882
- Product name
- Fmoc-NMe-PEG4-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $780
- Updated
- 2021/12/16
Fmoc-NMe-PEG4-acid Chemical Properties,Usage,Production
Description
Fmoc-NMe-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Fmoc-NMe-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-NMe-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-NMe-PEG4-acid Suppliers
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View Lastest Price from Fmoc-NMe-PEG4-acid manufacturers
- Product
- Fmoc-NMe-PEG4-acid 2170240-98-7
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25