Amino-PEG5-t-butyl acetate
- Product Name
- Amino-PEG5-t-butyl acetate
- CAS No.
- 2231845-67-1
- Chemical Name
- Amino-PEG5-t-butyl acetate
- Synonyms
- NH2-PEG5-C1-Boc;H2N-PEG5-CH2COOtBu;NH2-PEG5-CH2COOtBu;Amino-PEG5-CH2COOtBu;Amino-PEG5-t-butyl acetate;tert-butyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate;1,1-Dimethylethyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate;3,6,9,12,15-Pentaoxaheptadecanoic acid,17-amino-, 1,1-dimethylethyl ester;H2N-PEG5-CH2COOtBu/3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
- CBNumber
- CB14858565
- Molecular Formula
- C16H33NO7
- Formula Weight
- 351.44
- MOL File
- 2231845-67-1.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B-1410
- Product name
- H2N-PEG5-CH2COOtBu
- Purity
- 97%
- Packaging
- 1g
- Price
- $421.7
- Updated
- 2021/12/16
Amino-PEG5-t-butyl acetate Chemical Properties,Usage,Production
Uses
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Amino-PEG5-t-butyl acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG5-t-butyl acetate Suppliers
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View Lastest Price from Amino-PEG5-t-butyl acetate manufacturers
- Product
- NH2-PEG5-CH2COOtBu 2231845-67-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2026-01-28