ChemicalBook > CAS DataBase List > Pentoxyverine

Pentoxyverine

Product Name
Pentoxyverine
CAS No.
77-23-6
Chemical Name
Pentoxyverine
Synonyms
PENTOXIFYLLINE;Urex;Carbetapentane;Tuclase;Pentoxyverine Base;ucb2543;Atussil;Sedotussin;u.c.b.2543;U.C.B. 2543
CBNumber
CB1497317
Molecular Formula
C20H31NO3
Formula Weight
333.46
MOL File
77-23-6.mol
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Pentoxyverine Property

Boiling point:
165-170 °C (1.33Pa)
Density 
1.048±0.06 g/cm3(Predicted)
refractive index 
1.4990-1.5010
storage temp. 
Refrigerator
solubility 
Dichloromethane (Slightly), Methanol (Slightly)
pka
9.69±0.25(Predicted)
form 
Oil
color 
Clear Very Dark Red to Brown
CAS DataBase Reference
77-23-6(CAS DataBase Reference)
NIST Chemistry Reference
1-Cyclopentanecarboxylate, 2-(diethylaminoethoxy)ethyl-1-phenyl-(77-23-6)
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Safety

Hazardous Substances Data
77-23-6(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 150mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C178025
Product name
Carbetapentane
Packaging
50mg
Price
$135
Updated
2021/12/16
TRC
Product number
C178025
Product name
Carbetapentane
Packaging
100mg
Price
$215
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007262
Product name
PENTOXYVERINE
Purity
95.00%
Packaging
1MG
Price
$401.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007262
Product name
PENTOXYVERINE
Purity
95.00%
Packaging
5G
Price
$2150
Updated
2021/12/16
AHH
Product number
API-1156
Product name
Carbetapentane
Purity
98%
Packaging
10g
Price
$710
Updated
2021/12/16
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Pentoxyverine Chemical Properties,Usage,Production

Originator

Asthma ,Nichiiko

Uses

Carbetapentane is an antitussive anticonvulsant sigma site agonist.

Definition

ChEBI: 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester is a member of benzenes.

Manufacturing Process

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.

brand name

Toclase (Pfizer).

Therapeutic Function

Antitussive

Pentoxyverine Preparation Products And Raw materials

Raw materials

α-Phenylcyclopentanecarbonyl chloride 1-Phenylcyclopentanecarboxylic acid phenylacetonitrile Sesamol Calcium chloride Trichloroethylene Diethylamine 1,4-Dibromobutane 1-Phenyl-1-cyclopentanecarbonitrile

Preparation Products

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View Lastest Price from Pentoxyverine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Pentoxyverine Citrite 77-23-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000KG
Release date
2021-11-23
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Pentoxyverine 77-23-6
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-09-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
Pentoxyverine 77-23-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

77-23-6, PentoxyverineRelated Search:

Ethylbenzene Methylcyclopentane CARBETAPENTANE CITRATE,CARBETAPENTANE CITRATE SALT,PENTOXYVERINE CITRATE RESMETHRIN Bromocyclopentane Ethyl acrylate Ethylparaben Cyclopentyl chloride Ethyl formate Ethyl acetate 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester Ethyl propionate acetic acid, triethoxy-, ethyl ester Ethanol Cyclopentane PIPERAZINE CITRATE HYDRATE Clomiphene Citrate Ranitidinebismuthcitrate

  • 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester
  • 1-phenyl-1-cyclopentanecarboxylate
  • 1-Phenylcyclopentane-1-Carboxylic acid diethylaminoethoxyethyl ester
  • 1-phenylcyclopentane-1-carboxylicaciddiethylaminoethoxyethylester
  • 1-phenyl-cyclopentanecarboxylicaci2-(2-(diethylamino)ethoxy)ethylester
  • 1-phenylcyclopentanecarboxylicacid2-(2-diethylaminoethoxy)ethylester
  • ucb2543
  • Urex
  • Pentoxyverine Base
  • CARETAPENTANE
  • Carbetapentane (base and/or unspecified salts)
  • PENTOXIFYLLINE
  • 2-(2-DIETHYLAMINOETHOXY)ETHYL 1-PHENYLCYCLOPENTANECARBOXYLATE CITRATE
  • 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane
  • 1-Phenylcyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl
  • 1-phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethyloxy)ethyl ester
  • 2-(2-diethylaminoethyloxy)ethyl 1-phenylcyclopentane-1-carboxylate
  • 2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentane-1-carboxylate
  • Carbetapentane
  • PENTOSYVERINECITRATE
  • Pentoxyverine citrate (Carbetapentane)
  • 2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentanecarboxylate
  • 2-(2-diethylaminoethoxy)ethyl1-phenylcyclopentanecarboxylate
  • 2-(Diethylaminoethoxy)ethyl 1-phenyl-1-cyclopentanecarboxylate
  • 2-(Diethylaminoethoxy)ethyl 1-phenylcyclopentyl-1-carboxylate
  • 2-(diethylaminoethoxy)ethyl1-phenyl-1-cyclopentanecarboxylate
  • 2-(diethylaminoethoxy)ethyl1-phenylcyclopentyl-1-carboxylate
  • 2-[2-(Diemthylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate
  • Atussil
  • Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
  • Ethanol, 2-[2-(diethylamino)ethoxy]-, 1-phenylcyclopentanecarboxylate (ester)
  • Pentoxiverin
  • Pentoxiverine
  • Pentoxyverin
  • Pentoxyverine
  • Sedotussin
  • Tuclase
  • U.C.B. 2543
  • u.c.b.2543
  • Pentoxyverine USP/EP/BP
  • Pentoxyverine Citrite
  • Cough will clear
  • Pentoxyverine Monomer
  • 77-23-6
  • C26H39NO10
  • Miscellaneous Biochemicals