PYRROLNITRIN
- Product Name
- PYRROLNITRIN
- CAS No.
- 1018-71-9
- Chemical Name
- PYRROLNITRIN
- Synonyms
- 52230;A-10338;pyroace;nsc-107654;pyrollnitrin;Pyrrolnitrine;Antibiotic A-10338;3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol;PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)-;3-chloro-4-(2’-nitro-3’-chlorophenyl)pyrrole
- CBNumber
- CB1498369
- Molecular Formula
- C10H6Cl2N2O2
- Formula Weight
- 257.07
- MOL File
- 1018-71-9.mol
PYRROLNITRIN Property
- Melting point:
- 124.5°
- Boiling point:
- 410.5±45.0 °C(Predicted)
- Density
- 1.5834 (rough estimate)
- refractive index
- 1.6100 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 10 mM
- form
- A solid
- pka
- 14.28±0.50(Predicted)
Safety
- Toxicity
- LD50 in rats, rabbits (mg/kg): 68, 105 i.p. (Nishida)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P8861
- Product name
- Pyrrolnitrin from Pseudomonas cepacia
- Purity
- ≥98% (HPLC), solid
- Packaging
- 1MG
- Price
- $385
- Updated
- 2023/06/20
- Product number
- API0008411
- Product name
- PYRROLNITRIN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $994.68
- Updated
- 2021/12/16
PYRROLNITRIN Chemical Properties,Usage,Production
Description
Pyrrolnitrin, isolated from Pseudomonas species, is highly active against fungi, particularly trichophyte species.
Uses
Antifungal.
Uses
Pyrrolnitrin from Pseudomonas cepacia has been used as a standard in the detection of pyrrolnitrin in Serratia marcescens cell culture extract.
Definition
ChEBI: A member of the class of pyrroles carrying chloro and 3-chloro-2-nitrophenyl substituents at positions 3 and 4 respectively.
Origin
Pyrrolnitrin was found in the cells of Pseudomonas pyrrocinia grownin a medium containing a high concentration of inorganic phosphate.It was discovered by Arima of the University of Tokyo in collaboration with Fujisawa Pharmaceutical Industries Co. in 1965.
Biological Activity
Pyrrolnitrin shows strong activity against a variety of fungi and weak activity against grampositive bacteria.
Biochem/physiol Actions
Pyrrolnitrin blocks the terminal electron transport between succinate or reduced NADH and coenzyme Q. In mitochondria preparations of S. cerevisiae, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cythochrome C reductase, and NADH-cytochrome C reductase. Pyrrolnitrin is involved in many cellular processes such as oxidative stress, electron transport, DNA and RNA synthesis.
PYRROLNITRIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PYRROLNITRIN manufacturers
- Product
- PYRROLNITRIN 1018-71-9
- Price
- US $8.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28