PYRROLNITRIN

Product Name: PYRROLNITRIN
CAS No.: 1018-71-9
Chemical Name: PYRROLNITRIN
Synonyms: 52230;A-10338;pyroace;nsc-107654;pyrollnitrin;Pyrrolnitrine;Antibiotic A-10338;3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol;PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)-;3-chloro-4-(2’-nitro-3’-chlorophenyl)pyrrole
CBNumber: CB1498369
Molecular Formula: C10H6Cl2N2O2
Formula Weight: 257.07
MOL File: 1018-71-9.mol

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PYRROLNITRIN Property

Melting point:: 124.5°
Boiling point:: 410.5±45.0 °C(Predicted)
Density: 1.5834 (rough estimate)
refractive index: 1.6100 (estimate)
storage temp.: Store at -20°C
solubility: DMSO: 10 mM
form: A solid
pka: 14.28±0.50(Predicted)

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Safety

Toxicity: LD50 in rats, rabbits (mg/kg): 68, 105 i.p. (Nishida)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P8861
Product name: Pyrrolnitrin from Pseudomonas cepacia
Purity: ≥98% (HPLC), solid
Packaging: 1MG
Price: $385
Updated: 2023/06/20

American Custom Chemicals Corporation

Product number: API0008411
Product name: PYRROLNITRIN
Purity: 95.00%
Packaging: 1MG
Price: $994.68
Updated: 2021/12/16

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PYRROLNITRIN Chemical Properties,Usage,Production

Description

Pyrrolnitrin, isolated from Pseudomonas species, is highly active against fungi, particularly trichophyte species.

Uses

Antifungal.

Uses

Pyrrolnitrin from Pseudomonas cepacia has been used as a standard in the detection of pyrrolnitrin in Serratia marcescens cell culture extract.

Definition

ChEBI: A member of the class of pyrroles carrying chloro and 3-chloro-2-nitrophenyl substituents at positions 3 and 4 respectively.

Origin

Pyrrolnitrin was found in the cells of Pseudomonas pyrrocinia grownin a medium containing a high concentration of inorganic phosphate.It was discovered by Arima of the University of Tokyo in collaboration with Fujisawa Pharmaceutical Industries Co. in 1965.

Biological Activity

Pyrrolnitrin shows strong activity against a variety of fungi and weak activity against grampositive bacteria.

Biochem/physiol Actions

Pyrrolnitrin blocks the terminal electron transport between succinate or reduced NADH and coenzyme Q. In mitochondria preparations of S. cerevisiae, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cythochrome C reductase, and NADH-cytochrome C reductase. Pyrrolnitrin is involved in many cellular processes such as oxidative stress, electron transport, DNA and RNA synthesis.

PYRROLNITRIN Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRROLNITRIN Suppliers

China 41 South Korea 1 Switzerland 1 United States 4 Global 47

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View Lastest Price from PYRROLNITRIN manufacturers

Henan Fengda Chemical Co., Ltd

Product: PYRROLNITRIN 1018-71-9
Price: US $8.00-1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

1018-71-9, PYRROLNITRINRelated Search:

2-Nitro-3-chlorotoluene PYRROLNITRIN

3-chloro-4-(2’-nitro-3’-chlorophenyl)pyrrole

3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol

nsc-107654

pyroace

pyrollnitrin

PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)-

52230

A-10338

Antibiotic A-10338

3-chloro-4-(3-chloro-2-nitro-phenyl)-1H-pyrrole

3-chloro-4-(3-chloro-2-nitrophenyl)-1H-pyrrole

1H-Pyrrole, 3-chloro-4-(3-chloro-2-nitrophenyl)-

Pyrrolnitrine

1018-71-9