ALOIN

ChemicalBook > CAS DataBase List > ALOIN

Product Name: ALOIN
CAS No.: 8015-61-0
Chemical Name: ALOIN
Synonyms: alloin;Aloins;Cafaloin;Jafaloin;Socaloin;Ai3-19097;Ugandaloin;Aloin, cape;ALOIN, CRUDE;ALOIN,POWDER
CBNumber: CB1502400
Molecular Formula: C21H22O9
Formula Weight: 418.39398
MOL File: 8015-61-0.mol

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ALOIN Property

storage temp.: 2-8°C
solubility: pyridine: 50 mg/mL, clear, dark red
form: Solid
color: Dark Yellow
Stability:: Hygroscopic
InChIKey: AFHJQYHRLPMKHU-GQMFJIQQNA-N
SMILES: C1(O)=C2C([C@H]([C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C3=C(C2=O)C(O)=CC=C3)=CC(CO)=C1 |&1:4,5,6,8,10,12,r|
EPA Substance Registry System: Aloin (8015-61-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 8

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A575423
Product name: Aloin(mixtureofAandB)
Packaging: 1g
Price: $65
Updated: 2021/12/16

TRC

Product number: A575423
Product name: Aloin(mixtureofAandB)
Packaging: 5g
Price: $265
Updated: 2021/12/16

ChemScene

Product number: CS-0032167
Product name: Aloin(mixtureofA&B)
Purity: 98.03%
Packaging: 1mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0032167
Product name: Aloin(mixtureofA&B)
Purity: 98.03%
Packaging: 10mg
Price: $150
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0001864
Product name: ALLOIN
Purity: 95.00%
Packaging: 5MG
Price: $505.52
Updated: 2021/12/16

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ALOIN Chemical Properties,Usage,Production

Description

Aloin is the major anthraquinone glycoside obtained from the Aloe species[1]. It exhibits anti-inflammatory and anti-oxidative activities[2]. As a quality standard compound based on the Chinese Pharmacopoeia (CHP), it has a wide range of pharmacological activities, including anti-tumor, anti-inflammatory, anti-osteoporotic, organ-protective, anti-viral, anti-microbial, anti-parasitic, and laxative potentials[3]. Moreover, it regulates blood lipids and glucose and improves neuropathic pain effects, depicting the potential to be transformed into promising medicines and healthcare products.

Uses

Aloin is used as a stimulant-laxative, treating constipation by inducing bowel movements. The compound is present in what is commonly referred to as the aloe latex that exudes from cells adjacent to the vascular bundles, found under the rind of the leaf and in between it and the gel.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

References

[1] Lee L, et al. Inhibitory effects of aloin on TGFBIp-mediated septic responses. Journal of Asian Natural Products Research, 2020; 23: 189-203.
[2] Lee L, et al.Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses. Journal of Asian Natural Products Research, 2020; 23: 89-99.
[3] Yang Y, et al.Can aloin develop to medicines or healthcare products?. Biomedicine Pharmacotherapy, 2022; 153: 113421.

ALOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ALOIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: ALOIN 8015-61-0
Price: US $80.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-04-23

Career Henan Chemical Co

Product: ALOIN 8015-61-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-02-17

8015-61-0, ALOINRelated Search:

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Aloins

IsobarbaloinoderDecacetyllittoraloin

ALOIN,POWDER

alloin

ALOIN, CRUDE

9(10H)-Anthracenone, 10-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-

Ai3-19097

Aloin, cape

Aloin, curaco

Aloin(Mixture of A&B)

Cafaloin

Jafaloin

Socaloin

Ugandaloin

barbaloin AB

Aloin (Mixture of A and B)

(1S)-1,5-Anhydro-1-[(9S)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9 ,10-dihydro-9-anthracenyl]-D-glucitol

Aloin (mixture A&B)

(S)-1,8-Dihydroxy-3-(hydroxymethyl)-10-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)anthracen-9(10H)-one(Mixture of A and B)

Aloe vera stock solution

8015-61-0