ChemicalBook > CAS DataBase List > ALOIN

ALOIN

Product Name
ALOIN
CAS No.
8015-61-0
Chemical Name
ALOIN
Synonyms
alloin;Aloins;Cafaloin;Jafaloin;Socaloin;Ai3-19097;Ugandaloin;Aloin, cape;ALOIN, CRUDE;ALOIN,POWDER
CBNumber
CB1502400
Molecular Formula
C21H22O9
Formula Weight
418.39398
MOL File
8015-61-0.mol
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ALOIN Property

storage temp. 
2-8°C
solubility 
pyridine: 50 mg/mL, clear, dark red
form 
Solid
color 
Dark Yellow
Stability:
Hygroscopic
InChIKey
AFHJQYHRLPMKHU-GQMFJIQQNA-N
SMILES
C1(O)=C2C([C@H]([C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C3=C(C2=O)C(O)=CC=C3)=CC(CO)=C1 |&1:4,5,6,8,10,12,r|
EPA Substance Registry System
Aloin (8015-61-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
8
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A575423
Product name
Aloin(mixtureofAandB)
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
A575423
Product name
Aloin(mixtureofAandB)
Packaging
5g
Price
$265
Updated
2021/12/16
ChemScene
Product number
CS-0032167
Product name
Aloin(mixtureofA&B)
Purity
98.03%
Packaging
1mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0032167
Product name
Aloin(mixtureofA&B)
Purity
98.03%
Packaging
10mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001864
Product name
ALLOIN
Purity
95.00%
Packaging
5MG
Price
$505.52
Updated
2021/12/16
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ALOIN Chemical Properties,Usage,Production

Description

Aloin is the major anthraquinone glycoside obtained from the Aloe species[1]. It exhibits anti-inflammatory and anti-oxidative activities[2]. As a quality standard compound based on the Chinese Pharmacopoeia (CHP), it has a wide range of pharmacological activities, including anti-tumor, anti-inflammatory, anti-osteoporotic, organ-protective, anti-viral, anti-microbial, anti-parasitic, and laxative potentials[3]. Moreover, it regulates blood lipids and glucose and improves neuropathic pain effects, depicting the potential to be transformed into promising medicines and healthcare products.

Uses

Aloin is used as a stimulant-laxative, treating constipation by inducing bowel movements. The compound is present in what is commonly referred to as the aloe latex that exudes from cells adjacent to the vascular bundles, found under the rind of the leaf and in between it and the gel.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

References

[1] Lee L, et al. Inhibitory effects of aloin on TGFBIp-mediated septic responses. Journal of Asian Natural Products Research, 2020; 23: 189-203.
[2] Lee L, et al.Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses. Journal of Asian Natural Products Research, 2020; 23: 89-99.
[3] Yang Y, et al.Can aloin develop to medicines or healthcare products?. Biomedicine Pharmacotherapy, 2022; 153: 113421.

ALOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALOIN Suppliers

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View Lastest Price from ALOIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
ALOIN 8015-61-0
Price
US $80.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-23
Hebei Mojin Biotechnology Co., Ltd
Product
ALOIN 8015-61-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-30
Career Henan Chemical Co
Product
ALOIN 8015-61-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-17

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