ChemicalBook > CAS DataBase List > N-BOC-M-PHENYLENEDIAMINE

N-BOC-M-PHENYLENEDIAMINE

Product Name
N-BOC-M-PHENYLENEDIAMINE
CAS No.
68621-88-5
Chemical Name
N-BOC-M-PHENYLENEDIAMINE
Synonyms
3-(Boc-amino)aniline;Boc-m-phenylenediamine;N-BOC-m-Phenylenediaimne;N-Boc-1,3-phenylenediaMine;tert-butyl (3-aminophenyl)carbam;N-BOC-M-PHENYLENEDIAMINE，98% min;tert-butyl N-(3-aMinophenyl)carbaMate;N-Boc-m-phenylenediamine;N-Boc-m-phenylenediamine >=98.0% (HPLC);1,1-Dimethylethyl (3-aminophenyl)carbamate
CBNumber
CB1502697
Molecular Formula
C11H16N2O2
Formula Weight
208.26
MOL File
68621-88-5.mol
More
Less

N-BOC-M-PHENYLENEDIAMINE Property

Melting point:
109-110℃ (dichloromethane )
Boiling point:
295.1±23.0 °C(Predicted)
Density 
1.152±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
slightly sol. in Methanol
form 
powder to crystal
pka
13.57±0.70(Predicted)
color 
White to Gray to Brown
InChI
InChI=1S/C11H16N2O2/c1-11(2,3)15-10(14)13-9-6-4-5-8(12)7-9/h4-7H,12H2,1-3H3,(H,13,14)
InChIKey
IEUIEMIRUXSXCL-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NC1=CC=CC(N)=C1
CAS DataBase Reference
68621-88-5
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
F 
10-23
HS Code 
2924297099
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
53175
Product name
N-Boc-m-phenylenediamine
Purity
≥98.0% (HPLC)
Packaging
5g
Price
$179
Updated
2025/07/31
TCI Chemical
Product number
B4222
Product name
N-(tert-Butoxycarbonyl)-1,3-phenylenediamine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
B4222
Product name
N-(tert-Butoxycarbonyl)-1,3-phenylenediamine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$203
Updated
2025/07/31
TRC
Product number
B663295
Product name
N-Boc-m-Phenylenediamine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B663295
Product name
N-Boc-m-Phenylenediamine
Packaging
500mg
Price
$75
Updated
2021/12/16
More
Less

N-BOC-M-PHENYLENEDIAMINE Chemical Properties,Usage,Production

Uses

N-Boc-m-phenylenediamine (tert-Butyl-3-aminophenylcarbamate) may be used in the preparation of:

  • 5,5′-(propane-2,2-diyl)bis(N-(3-aminophenyl)-4-methyl-3-phenyl-1H-pyrrole-2-carboxamide)
  • ethyl 4-[{3-[(tert-butoxycarbonyl)amino]phenyl}amino]-2-chloropyrimidine-5-carboxylate
  • ethyl 4-(3-(tert-butoxycarbonyl)phenylamino)-2-(methylthio)pyrimidine-5-carboxylate

reaction suitability

reagent type: cross-linking reagent

Synthesis

18437-64-4

68621-88-5

General procedure: tert-butyl (3-nitrophenyl)carbamate (10.75 g, 45.12 mmol) was used as raw material and dissolved in methanol (150 mL). To this solution, 10% Pd/C catalyst (0.48 g) was added. The reaction mixture was stirred overnight at room temperature in a hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (4:1, v/v) to give N-BOC-mesophenylenediamine as a light yellow solid (7.59 g, 8% yield).

References

[1] Tetrahedron Letters, 1993, vol. 34, # 49, p. 7823 - 7826
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 4, p. 623 - 639
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 7, p. 2253 - 2261
[4] Journal of the American Chemical Society, 2008, vol. 130, # 45, p. 15193 - 15202
[5] Journal of Medicinal Chemistry, 2015, vol. 58, # 1, p. 212 - 221

N-BOC-M-PHENYLENEDIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-BOC-M-PHENYLENEDIAMINE Suppliers

Americas 1 China 177 Europe 2 Germany 3 India 7 Japan 1 Switzerland 2 United Kingdom 7 United States 29 Global 229
Shanghai Dano Pharmaceutical Co., LTD(China)
Tel
0592-6266840 15750707980
Email
sales@chemsdano.com
Country
China
ProdList
357
Advantage
57
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
zwchem@163.com
Country
China
ProdList
616
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Sphinx Scientific Laboratory (Tianjin) Co., Ltd.
Tel
022-66211289-843 13672102692
Fax
QQ：2377893365
Email
contact@sphinxpharm.com
Country
China
ProdList
361
Advantage
62
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Heterochem
Tel
027-88041443 13072715837
Fax
027-51829379
Email
sales@hetero-chem.com
Country
China
ProdList
696
Advantage
58
Jinan Bond Chemical Technology Co., Ltd.
Tel
86-531-88280989
Fax
86-531-88280989
Email
mymail1996@126.com
Country
China
ProdList
256
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1999
Advantage
58
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
4131
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Shanghai SunSyn Pharmaceutical Co., Ltd.
Tel
18621020637 18621020637;
Email
sales@sunsynpharma.com
Country
China
ProdList
288
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai D&B Biological Science and Technology Co.Ltd
Tel
400-008-9730,021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3057
Advantage
60
Tianjin Olefin Pharmaceutical Co., Ltd.
Tel
022-022-23301225 18202662021
Fax
022-25541300
Email
Mingmingxuetsu@163.com
Country
China
ProdList
313
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Beijing FYF Chemicals Co., Ltd
Tel
010-57903446 15869909019
Fax
010-57903446
Email
168931144@qq.com
Country
China
ProdList
2875
Advantage
58
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243 13981822079;18682730901
Email
sales@ampebiochem.com
Country
China
ProdList
1000
Advantage
58
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 13583611556
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
300
Advantage
58
Shandong Boluoda Biological Technology Co., Ltd.
Tel
0531-68652053 15863796298;
Email
2310993908@qq.com
Country
China
ProdList
2437
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
1250
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
More
Less

View Lastest Price from N-BOC-M-PHENYLENEDIAMINE manufacturers

Shanghai Yingrui Biopharma Co.,Ltd
Product
N-BOC-M-PHENYLENEDIAMINE 68621-88-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
10Tons
Release date
2019-11-07
Shanghai Yingrui Biopharma Co.,Ltd
Product
N-BOC-M-PHENYLENEDIAMINE 68621-88-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
10Tons
Release date
2019-11-07
Career Henan Chemical Co
Product
N-BOC-M-PHENYLENEDIAMINE 68621-88-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-15

68621-88-5, N-BOC-M-PHENYLENEDIAMINERelated Search:

(5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (3-AMINO-2-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (5-AMINO-2-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (5-AMINO-2-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (3-BOC-AMINO-5-NITROPHENYL)BORONIC ACID (3-AMINO-4-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (5-AMINO-2-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER BOC-3-AMINO-5-(FMOC-AMINO)-BENZOIC ACID (3-AMINO-4-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER 3,5-BIS-BOC-AMINOBENZOIC ACID (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER N,N-DI-TERT-BUTOXYCARBONYL-BENZENE-1,3-DIAMINE N-BOC-M-PHENYLENEDIAMINE (5-AMINO-2-METHOXY-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER 3-T-BUT-(OXYCARBOXYLAMINO-5-NITROPHENYL) CARBAMIC ACID T-BUTYL ESTER 2-TERT-BUTOXYCARBONYLAMINO-4-NITROBENZOIC ACID AURORA KA-8078

  • Carbamic acid, (3-aminophenyl)-, 1,1-dimethylethyl ester (9CI)
  • CarbaMic acid, N-(3-aMinophenyl)-, 1,1-diMethylethyl ester
  • CarbaMic acid, (3-aMinophenyl)-, 1,1-diMethylethyl ester
  • tert-butyl N-(3-aMinophenyl)carbaMate
  • 3-(tert-Butoxycarbonylamino)aniline, tert-Butyl-3-aminophenylcarbamate
  • N-Boc-1,3-phenylenediaMine
  • 1,1-Dimethylethyl (3-aminophenyl)carbamate
  • Boc-m-phenylenediamine
  • N-(tert-Butoxycarbonyl)-benzene-1,3-diamine
  • (3-aMinophenyl)carbaMic acid, 1,1-diMethylethyl ester
  • N-(tert-Butoxycarbonyl)-1,3-phenylenediaMine
  • N-BOC-m-Phenylenediaimne
  • tert-butyl (3-aminophenyl)carbam
  • N-Boc-m-phenylenediamine >=98.0% (HPLC)
  • N-(tert-Butoxycarbonyl)-1,3-phenylenediamine &gt
  • 3-(Boc-amino)aniline
  • <i>N</i>-Boc-<i>m</i>-phenylenediamine
  • N-BOC-M-PHENYLENEDIAMINE，98% min
  • 68621-88-5
  • N-BOC