TELENZEPINE 2HCL

Product Name: TELENZEPINE 2HCL
CAS No.: 80880-90-6
Chemical Name: TELENZEPINE 2HCL
Synonyms: SK-871;Telenzepine;TELENZEPINE 2HCL;telenzepine dihydrochloride hydrate;1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one;10H-Thieno[3,4-b][1,5]benzodiazepin-10-one, 4,9-dihydro-3-methyl-4-[2-(4-methyl-1-piperazinyl)acetyl]-;4,9-dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10h-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrobromide
CBNumber: CB1504787
Molecular Formula: C19H22N4O2S
Formula Weight: 370.475
MOL File: 80880-90-6.mol

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TELENZEPINE 2HCL Property

Melting point:: 263-264°
Boiling point:: 544.7±50.0 °C(Predicted)
Density: 1.281±0.06 g/cm3(Predicted)
solubility: H₂O: >10 mg/mL
pka: 12.48±0.20(Predicted)
form: solid
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0015667
Product name: TELENZEPINE
Purity: 95.00%
Packaging: 10MG
Price: $255.15
Updated: 2021/12/16

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TELENZEPINE 2HCL Chemical Properties,Usage,Production

Uses

Telenzepine is an antimuscarinic agent with Kis of 0.94 nM (M1 mAChR) and 17.8 nM (M2 mAChR) binding to muscarinic receptors. Telenzepine effectively blocks synaptic transmission promoted by muscarinic or M1 receptor agonists. Thus, Telenzepine can reduce the amplitude of extracellular slow excitatory postsynaptic potentials (EC50=38 nM) and slow inhibitory postsynaptic potentials (EC50=253 nM)[1].

Definition

ChEBI: 1-methyl-10-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one is a benzodiazepine.

References

[1] Telenzepine. IMGT. DOI:10.1016/0014-2999(89)90741-3

TELENZEPINE 2HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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TELENZEPINE 2HCL Suppliers

China 4 United States 2 Global 6

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80880-90-6, TELENZEPINE 2HCLRelated Search:

1-(2-DIMETHYLAMINOETHYL)-4-METHYLPIPERAZINE N-3-thienylacetamide N-Aminoethylpiperazine N-METHYL-N-PHENYL-2-PIPERAZIN-1-YLACETAMIDE 4-Methyl-1-piperazineethanamine TELENZEPINE 2HCL N,N-DIMETHYL-2-PIPERAZIN-1-YL-ACETAMIDE 1-(4-CHLOROBENZYL)PIPERAZINE 2-PIPERAZIN-1-YL-ACETAMIDE N-(2-AMINO-ETHYL)-BENZENE-1,2-DIAMINE 3-THIOPHENECARBOXAMIDE 98 1-Piperazineethanamine,N,4-dimethyl-(9CI) N-(2-aminophenyl)-2-(4-methylpiperazin-1-yl)acetamide N1-(2-AMINOPHENYL)-N2,N2-DIMETHYLGLYCINAMIDE 3-AMINO-4-METHYLTHIOPHENE (4-METHYL-PIPERAZIN-1-YL)-ACETALDEHYDE N-[2-(DIMETHYLAMINO)ETHYL]BENZENE-1,2-DIAMINE METHYL-THIOPHEN-3-YLMETHYL-AMINE

TELENZEPINE 2HCL

Telenzepine

4,9-dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10h-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrobromide

telenzepine dihydrochloride hydrate

SK-871

1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one

10H-Thieno[3,4-b][1,5]benzodiazepin-10-one, 4,9-dihydro-3-methyl-4-[2-(4-methyl-1-piperazinyl)acetyl]-

80880-90-6