4-Methyl-1-piperazineethanamine
Uses- Product Name
- 4-Methyl-1-piperazineethanamine
- CAS No.
- 934-98-5
- Chemical Name
- 4-Methyl-1-piperazineethanamine
- Synonyms
- AKOS BB-6128;CHEMBRDG-BB 4006383;4-Methylpiperazin-1-ethylamin;4-methylpiperazine-1-ethylamine;4-METHYL-1-PIPERAZINEETHANAMINE;1-(2-AMINOETHYL)METHYLPIPERAZINE;1-Piperazineethanamine, 4-methyl-;1-(2-Aminoethyl)-4-methyl-piperaz;1-Methyl-4-(2-aminoethyl)piperazine;2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE
- CBNumber
- CB6721134
- Molecular Formula
- C7H17N3
- Formula Weight
- 143.23
- MOL File
- 934-98-5.mol
4-Methyl-1-piperazineethanamine Property
- Boiling point:
- 103°C/11.25mm
- Density
- 0.956±0.06 g/cm3(Predicted)
- refractive index
- 1.4780
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- liquid
- pka
- 10.11±0.10(Predicted)
- color
- Colourless to light yellow
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
- InChIKey
- GOWUDHPKGOIDIX-UHFFFAOYSA-N
- SMILES
- N1(CCN)CCN(C)CC1
- CAS DataBase Reference
- 934-98-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- RIDADR
- 2735
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CDS003000
- Product name
- 2-(4-Methyl-piperazin-1-yl)-ethylamine
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $87.5
- Updated
- 2025/07/31
- Product number
- M3597
- Product name
- 2-(4-Methylpiperazin-1-yl)ethan-1-amine
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $63
- Updated
- 2025/07/31
- Product number
- M725980
- Product name
- 2-(4-Methylpiperazin-1-yl)ethanamine
- Packaging
- 2.5g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- OR0800
- Product name
- 1-(2-Aminoethyl)-4-methylpiperazine
- Purity
- 95%
- Packaging
- 5g
- Price
- $106
- Updated
- 2021/12/16
- Product number
- 030836
- Product name
- 2-(4-Methyl-piperazin-1-yl)-ethylamine
- Packaging
- 5g
- Price
- $89
- Updated
- 2021/12/16
4-Methyl-1-piperazineethanamine Chemical Properties,Usage,Production
Uses
2-(4-Methylpiperazin-1-yl)ethanamine (cas# 934-98-5) is a useful research chemical.
Chemical Properties
Colorless liquid
Uses
1-(2-Aminoethyl)-4-methylpiperazine is used as pharmaceutical intermediate.
Definition
ChEBI: A N-alkylpiperazine that is piperazine substituted by a methyl and a 2-aminoethyl group at the N atoms respectively.
Synthesis
874-77-1
934-98-5
Step 5. To a stirred suspension of lithium aluminum hydride (3.3 g, 87 mmol) in anhydrous THF (100 mL) was slowly added a solution of 2-(4-methylpiperazin-1-yl)acetonitrile (11.2 g, 80.4 mmol) in anhydrous THF (300 mL) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the mixture was cooled in an ice bath and H2O (3.3 mL) and 20% NaOH solution (3.3 mL) were added sequentially. After stirring for 20 minutes, the mixture was filtered and the solvent was evaporated. The residue was dissolved in ethyl acetate and dried with anhydrous sodium sulfate. The solvent was evaporated to dryness to give 2-(4-methylpiperazin-1-yl)ethylamine as an oil (1.15 g, 99%).1H NMR (400 MHz, CDCl3) δ: 2.21 (s, 3H), 2.20-2.60 (m, 10H), 2.71 (t, J=6.0 Hz, 2H).
References
[1] Journal of Medicinal Chemistry, 1999, vol. 42, # 15, p. 2870 - 2880
[2] Patent: WO2013/148365, 2013, A1. Location in patent: Paragraph 0086
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 7, p. 2251 - 2259
[4] Patent: WO2016/16728, 2016, A2. Location in patent: Paragraph 000703; 000704
[5] Patent: WO2005/35532, 2005, A1. Location in patent: Page/Page column 30
4-Methyl-1-piperazineethanamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Methyl-1-piperazineethanamine manufacturers
- Product
- 4-Methyl-1-piperazineethanamine 934-98-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%minGC
- Supply Ability
- 1ton/month
- Release date
- 2021-11-05
- Product
- 4-Methyl-1-piperazineethanamine 934-98-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 90%-99.99%
- Supply Ability
- 500kgs
- Release date
- 2019-07-02