ChemicalBook > CAS DataBase List > 4-Methyl-1-piperazineethanamine
4-Methyl-1-piperazineethanamine
Uses- Product Name
- 4-Methyl-1-piperazineethanamine
- CAS No.
- 934-98-5
- Chemical Name
- 4-Methyl-1-piperazineethanamine
- Synonyms
- AKOS BB-6128;CHEMBRDG-BB 4006383;4-Methylpiperazin-1-ethylamin;4-methylpiperazine-1-ethylamine;4-METHYL-1-PIPERAZINEETHANAMINE;1-(2-AMINOETHYL)METHYLPIPERAZINE;1-Piperazineethanamine, 4-methyl-;1-(2-Aminoethyl)-4-methyl-piperaz;1-Methyl-4-(2-aminoethyl)piperazine;2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE
- CBNumber
- CB6721134
- Molecular Formula
- C7H17N3
- Formula Weight
- 143.23
- MOL File
- 934-98-5.mol
More
Less
4-Methyl-1-piperazineethanamine Property
- Boiling point:
- 103°C/11.25mm
- Density
- 0.956±0.06 g/cm3(Predicted)
- refractive index
- 1.4780
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- liquid
- pka
- 10.11±0.10(Predicted)
- color
- Colourless to light yellow
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
- InChIKey
- GOWUDHPKGOIDIX-UHFFFAOYSA-N
- SMILES
- N1(CCN)CCN(C)CC1
- CAS DataBase Reference
- 934-98-5(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- RIDADR
- 2735
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29339900
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- CDS003000
- Product name
- 2-(4-Methyl-piperazin-1-yl)-ethylamine
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $87.5
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M3597
- Product name
- 2-(4-Methylpiperazin-1-yl)ethan-1-amine
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $63
- Updated
- 2025/07/31
TRC
- Product number
- M725980
- Product name
- 2-(4-Methylpiperazin-1-yl)ethanamine
- Packaging
- 2.5g
- Price
- $130
- Updated
- 2021/12/16
Apolloscientific
- Product number
- OR0800
- Product name
- 1-(2-Aminoethyl)-4-methylpiperazine
- Purity
- 95%
- Packaging
- 5g
- Price
- $106
- Updated
- 2021/12/16
Oakwood
- Product number
- 030836
- Product name
- 2-(4-Methyl-piperazin-1-yl)-ethylamine
- Packaging
- 5g
- Price
- $89
- Updated
- 2021/12/16
More
Less
4-Methyl-1-piperazineethanamine Chemical Properties,Usage,Production
Uses
2-(4-Methylpiperazin-1-yl)ethanamine (cas# 934-98-5) is a useful research chemical.
Chemical Properties
Colorless liquid
Uses
1-(2-Aminoethyl)-4-methylpiperazine is used as pharmaceutical intermediate.
Definition
ChEBI: A N-alkylpiperazine that is piperazine substituted by a methyl and a 2-aminoethyl group at the N atoms respectively.
Synthesis
874-77-1
934-98-5
Step 5. To a stirred suspension of lithium aluminum hydride (3.3 g, 87 mmol) in anhydrous THF (100 mL) was slowly added a solution of 2-(4-methylpiperazin-1-yl)acetonitrile (11.2 g, 80.4 mmol) in anhydrous THF (300 mL) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the mixture was cooled in an ice bath and H2O (3.3 mL) and 20% NaOH solution (3.3 mL) were added sequentially. After stirring for 20 minutes, the mixture was filtered and the solvent was evaporated. The residue was dissolved in ethyl acetate and dried with anhydrous sodium sulfate. The solvent was evaporated to dryness to give 2-(4-methylpiperazin-1-yl)ethylamine as an oil (1.15 g, 99%).1H NMR (400 MHz, CDCl3) δ: 2.21 (s, 3H), 2.20-2.60 (m, 10H), 2.71 (t, J=6.0 Hz, 2H).
References
[1] Journal of Medicinal Chemistry, 1999, vol. 42, # 15, p. 2870 - 2880
[2] Patent: WO2013/148365, 2013, A1. Location in patent: Paragraph 0086
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 7, p. 2251 - 2259
[4] Patent: WO2016/16728, 2016, A2. Location in patent: Paragraph 000703; 000704
[5] Patent: WO2005/35532, 2005, A1. Location in patent: Page/Page column 30
4-Methyl-1-piperazineethanamine Preparation Products And Raw materials
Raw materials
Acetonitrile
Ethanol
1-Methylpiperazine
Potassium carbonate
Nickel
Chloroacetonitrile
Benzaldehyde
Tetrahydrofuran
Diethyl ether
Ethyl acetate
Lithium Aluminum Hydride
Hydrochloric acid
Dichloromethane
Methanol
Sodium hydroxide
PETROLEUM ETHER
Preparation Products
More
Less
4-Methyl-1-piperazineethanamine Suppliers
- Tel
- 025-84112752 13805181430
- Fax
- +86-25-84846489
- 154301870@qq.com
- Country
- China
- ProdList
- 1000
- Advantage
- 55
- Tel
- 022-83946278 13820503911
- Fax
- 022-83945176
- sales@creasyn.com
- Country
- China
- ProdList
- 957
- Advantage
- 68
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 18515581800 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 9400
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 010-56645598 13366904824
- Fax
- 01062230033
- bjkaida@163.com
- Country
- China
- ProdList
- 1618
- Advantage
- 59
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- +86-027-87166955
- Fax
- +86-027-87166955
- wangjohnzen@hotmail.com wangjohnzen@gmail.com
- Country
- China
- ProdList
- 31
- Advantage
- 58
- Tel
- 010-57495520 13521095525
- zhw512@foxmail.com
- Country
- China
- ProdList
- 488
- Advantage
- 55
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 13770809694
- Fax
- +86 25 56203983
- googlexu_0114@sina.com
- Country
- China
- ProdList
- 990
- Advantage
- 58
- Tel
- 15618758386; 15618758386
- Fax
- QQ:3004479444
- sales3@myuchem.com
- Country
- China
- ProdList
- 1999
- Advantage
- 55
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 028-64353063
- Fax
- 028-64353063 QQ:784253935
- reacchemical@163.com
- Country
- China
- ProdList
- 5253
- Advantage
- 58
- Tel
- 028-67136579 15828051124
- sales@kamelpharm.com
- Country
- China
- ProdList
- 2294
- Advantage
- 55
- Tel
- 028-88469284 18000562381
- rzbtsj@163.com
- Country
- China
- ProdList
- 9951
- Advantage
- 56
- Tel
- 18915409046
- Fax
- 0510-86566870
- 1102409417@qq.com
- Country
- China
- ProdList
- 268
- Advantage
- 55
- Tel
- 021-20960837,QQ1332204249
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 3341
- Advantage
- 55
- Tel
- 022-83945173 18622315263
- Fax
- QQ1559208715
- export@creasyn.com
- Country
- China
- ProdList
- 490
- Advantage
- 55
- Tel
- 021-50908862，442785678，326799392 18721037013
- Fax
- 021-50908862
- siyansales@126.com
- Country
- China
- ProdList
- 9627
- Advantage
- 58
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 0371-55289822 18737195735
- Fax
- QQ：2370407954
- 2370407954@qq.com
- Country
- China
- ProdList
- 1981
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0751-2886750 13927877953
- Fax
- 0751-2886750
- 3005811397@qq.com
- Country
- China
- ProdList
- 13305
- Advantage
- 58
- Tel
- 400-086-3412 028-85062459
- Fax
- 028-85062459
- synguider@163.com
- Country
- China
- ProdList
- 3295
- Advantage
- 55
- Tel
- 2332782371
- Fax
- QQ: 2332782371
- adobechem@qq.com
- Country
- China
- ProdList
- 7980
- Advantage
- 58
- Tel
- 21-67759270 17717059219
- Fax
- QQ：1479352695
- sales@rlavie.com
- Country
- China
- ProdList
- 1620
- Advantage
- 55
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 022-59987777 13552403979
- jia_guoqiang@wuxiapptec.com
- Country
- China
- ProdList
- 22345
- Advantage
- 58
- Tel
- +86-（0）57185586718; +8613336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29735
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15083
- Advantage
- 58
More
Less
View Lastest Price from 4-Methyl-1-piperazineethanamine manufacturers
Shanghai Rlavie Technology Co ltd
- Product
- 4-Methyl-1-piperazineethanamine 934-98-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%minGC
- Supply Ability
- 1ton/month
- Release date
- 2021-11-05
Career Henan Chemical Co
- Product
- 4-Methyl-1-piperazineethanamine 934-98-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 90%-99.99%
- Supply Ability
- 500kgs
- Release date
- 2019-07-02
934-98-5, 4-Methyl-1-piperazineethanamineRelated Search:
Basic Violet 1
Methanol
(2-Methoxyethyl)benzene
1-Methylpiperazine
2-Ethylhexyl ferulate
Methyl acetate
2-(2-Aminoethylamino)ethanol
Acetonitrile
N-Aminoethylpiperazine
Methyl acrylate
Paraquat dichloride
Kresoxim-methyl
Methylparaben
Methyl
Methyl bromide
ALPHA-ERGOCRYPTINE
DIHYDROERGOTAMINE TARTRATE
1-(2-DIMETHYLAMINOETHYL)-4-METHYLPIPERAZINE