2-AMINO-5-METHOXYPYRIMIDINE
- Product Name
- 2-AMINO-5-METHOXYPYRIMIDINE
- CAS No.
- 13418-77-4
- Chemical Name
- 2-AMINO-5-METHOXYPYRIMIDINE
- Synonyms
- 5-Methoxy-2-pyrimidinamine;2-AMINO-5-METHOXYPYRIMIDINE;5-Methoxypyrimidin-2-ylamine;2-Pyrimidinamine, 5-methoxy-;2-Amino-5-methoxypyrimidine,97%;2-Pyrimidinamine, 5-methoxy- (9CI);2-AMINO-5-METHOXYPYRIMIDINE ISO 9001：2015 REACH
- CBNumber
- CB1506655
- Molecular Formula
- C5H7N3O
- Formula Weight
- 125.13
- MOL File
- 13418-77-4.mol
2-AMINO-5-METHOXYPYRIMIDINE Property
- Melting point:
- 86-88°C
- Boiling point:
- 313℃
- Density
- 1.224
- Flash point:
- 143℃
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform, Methanol
- pka
- 3.62±0.10(Predicted)
- form
- Powder
- color
- Off-white
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 13418-77-4
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A611958
- Product name
- 2-Amino-5-methoxypyrimidine
- Packaging
- 500mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- A1378-53
- Product name
- 2-Amino-5-methoxypyrimidine
- Packaging
- 500mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- A611958
- Product name
- 2-Amino-5-methoxypyrimidine
- Packaging
- 5g
- Price
- $1190
- Updated
- 2021/12/16
- Product number
- X9872
- Product name
- 2-Amino-5-methoxypyrimidine
- Packaging
- 1g
- Price
- $84
- Updated
- 2021/12/16
- Product number
- 119036
- Product name
- 2-Amino-5-methoxypyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $93
- Updated
- 2021/12/16
2-AMINO-5-METHOXYPYRIMIDINE Chemical Properties,Usage,Production
Chemical Properties
Yellow to Tan Solid
Synthesis
22536-65-8
13418-77-4
General procedure for the synthesis of 2-amino-5-methoxypyrimidine using 2-chloro-5-methoxypyrimidine as starting material: 2-chloro-5-methoxypyrimidine (0.817 g, 5.65 mmol) and 25% aqueous ammonia solution were added to a microwave reaction vessel. The reaction vessel was sealed and the reaction was heated at 150 °C for 3 hours. After completion of the reaction, the mixture was evaporated to dryness. The resulting crude product was dissolved in dichloromethane/methanol (1:1, v/v) solvent mixture and loaded on silica gel. Purification by fast column chromatography (eluent: 50-100% ethyl acetate in heptane solution with gradient elution) afforded 2-amino-5-methoxypyrimidine as colorless crystals (386 mg, 55% yield).1H NMR (400 MHz, DMSO-d6) δ 8.02 (s, 1H), 6.06 (br s, 1H), 3.71 (s, 3H).
References
[1] Patent: WO2008/141239, 2008, A1. Location in patent: Page/Page column 54
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 5, p. 1261 - 1266
2-AMINO-5-METHOXYPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-5-METHOXYPYRIMIDINE manufacturers
- Product
- 5-methoxypyrimidin-2-amine 13418-77-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 2-AMINO-5-METHOXYPYRIMIDINE 13418-77-4
- Price
- US $10.00/KG/Tin
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100
- Release date
- 2019-06-28