4-Pyrimidinamine, 2-methoxy- (9CI)

Product Name: 4-Pyrimidinamine, 2-methoxy- (9CI)
CAS No.: 3289-47-2
Chemical Name: 4-Pyrimidinamine, 2-methoxy- (9CI)
Synonyms: 2-methoxypyrimidin-4-amine;2-O-Methylcytosine;2-Methoxycytosine;2-Methoxy-4-PyriMidinaMine;4-AMINO-2-METHOXYPYRIMIDINE;4-Pyrimidinamine, 2-methoxy-;2-methoxypyrimidin-4(3H)-imine;(2-methoxypyrimidin-4-yl)amine;4-Pyrimidinamine, 2-methoxy- (9CI);4-Amino-2-neneneba methoxy pyrimidine
CBNumber: CB51081854
Molecular Formula: C5H7N3O
Formula Weight: 125.13
MOL File: 3289-47-2.mol

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4-Pyrimidinamine, 2-methoxy- (9CI) Property

Melting point:: 174 °C
Boiling point:: 294.4±32.0 °C(Predicted)
Density: 1.224
storage temp.: 2-8°C(protect from light)
solubility: DMSO: 60 mg/mL (479.50 mM)
pka: 4.97±0.10(Predicted)
form: solid
color: White to off white
InChI: InChI=1S/C5H7N3O/c1-9-5-7-3-2-4(6)8-5/h2-3H,1H3,(H2,6,7,8)
InChIKey: DHYLZDVDOQLEAQ-UHFFFAOYSA-N
SMILES: C1(OC)=NC=CC(N)=N1

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Safety

Hazard Codes: Xn
Risk Statements: 22-36-36/37/38-20/21/22
Safety Statements: 26-36/37/39
WGK Germany: 3
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS004264
Product name: 4-amino-2-methoxypyrimidine
Purity: AldrichCPR
Packaging: 100mg
Price: $73.1
Updated: 2025/07/31

TRC

Product number: M226398
Product name: 2-Methoxypyrimidin-4-amine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 295389
Product name: 4-Amino-2-methoxypyrimidine
Packaging: 1g
Price: $372
Updated: 2021/12/16

ApexBio Technology

Product number: C6576
Product name: 2-O-Methylcytosine
Packaging: 100mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NA57396
Product name: 4-Amino-2-methoxypyrimidine
Packaging: 1g
Price: $87.6
Updated: 2021/12/16

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4-Pyrimidinamine, 2-methoxy- (9CI) Chemical Properties,Usage,Production

Uses

2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase[1].

Definition

ChEBI: Pyrimidine substituted with a methoxy group at position C-2 and an amine group at C-4.

Synthesis

7461-50-9

3289-47-2

The general procedure for the synthesis of 4-amino-2-methoxypyrimidine from 2-chloro-4-aminopyrimidine is as follows: Pre-step A: Synthesis of 2-methoxy-4-pyrimidinamine 2-Chloro-4-pyrimidinamine (150 mg, 1.158 mmol) and sodium methanol (188 mg, 3.47 mmol) were dissolved in methanol (2.9 mL) and the mixture was heated to 100°C in a Biotage microwave reactor for 40 min. Upon completion of the reaction, the crude product was purified by reversed-phase high performance liquid chromatography (RP-HPLC) to afford 2-methoxy-4-pyrimidinamine (73 mg, 0.583 mmol, 50% yield). Mass spectrum (electrospray positive ion mode) m/z 126.0 ([M+H]+).

References

[1] Aliakbar Tehrani Z, et al. Comparison of gas phase intrinsic properties of cytosine and thymine nucleobases with their O-alkyl adducts: different hydrogen bonding preferences for thymine versus O-alkyl thymine. J Mol Model. 2013;19(8):2993‐3005. DOI:10.1007/s00894-013-1813-0

4-Pyrimidinamine, 2-methoxy- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Pyrimidinamine, 2-methoxy- (9CI) Suppliers

China 118 Europe 1 Germany 1 India 3 Switzerland 1 United Kingdom 3 United States 12 Global 139

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View Lastest Price from 4-Pyrimidinamine, 2-methoxy- (9CI) manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Pyrimidinamine, 2-methoxy- (9CI) 3289-47-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Career Henan Chemical Co

Product: 4-Pyrimidinamine, 2-methoxy- (9CI) 3289-47-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-03

3289-47-2, 4-Pyrimidinamine, 2-methoxy- (9CI)Related Search:

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4-Pyrimidinamine, 2-methoxy- (9CI)

4-AMINO-2-METHOXYPYRIMIDINE

2-methoxypyrimidin-4-amine

2-O-Methylcytosine

(2-methoxypyrimidin-4-yl)amine

4-Pyrimidinamine, 2-methoxy-

2-Methoxycytosine

2-Methoxypyrimidin-4-amine, 4-Amino-2-methoxy-1,3-diazine

2-Methoxy-4-PyriMidinaMine

2-methoxypyrimidin-4(3H)-imine

4-Pyrimidinamine, 2-methoxy- (9CI) ISO 9001：2015 REACH

4-Amino-2-neneneba methoxy pyrimidine

4-Amino-2-methoxypyrimidine, CAS 3289-47-2

3289-47-2

Heterocycle-Pyrimidine series

PYRIMIDINE