2-Mercaptothiazole
- Product Name
- 2-Mercaptothiazole
- CAS No.
- 5685-05-2
- Chemical Name
- 2-Mercaptothiazole
- Synonyms
- Thiazole-2(3H)-thione;Nsc 24294;Nsc 41217;1,3-thiazoL;2-Thiazolethiol;2-Mercaptothiazole;Thiazoline-2-thione;3H-thiazole-2-thione;4-Thiazoline-2-thione;2-Mercapto-1,3-thiazole
- CBNumber
- CB1512135
- Molecular Formula
- C3H3NS2
- Formula Weight
- 117.19
- MOL File
- 5685-05-2.mol
2-Mercaptothiazole Property
- Melting point:
- 80 °C(Solv: water (7732-18-5))
- Boiling point:
- 194.7±23.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 8.58±0.20(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C3H3NS2/c5-3-4-1-2-6-3/h1-2H,(H,4,5)
- InChIKey
- OCVLSHAVSIYKLI-UHFFFAOYSA-N
- SMILES
- S1C=CNC1=S
- LogP
- 1.213 (est)
- CAS DataBase Reference
- 5685-05-2(CAS DataBase Reference)
- NIST Chemistry Reference
- «delta»4-Thiazoline-2-thione(5685-05-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CHM0987523
- Product name
- 1,3-THIAZOLE-2(3H)-THIONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.06
- Updated
- 2021/12/16
- Product number
- A668171
- Product name
- Thiazole-2(3H)-thione
- Purity
- 95%
- Packaging
- 250mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- A668171
- Product name
- Thiazole-2(3H)-thione
- Purity
- 95%
- Packaging
- 1g
- Price
- $41
- Updated
- 2021/12/16
- Product number
- A668171
- Product name
- Thiazole-2(3H)-thione
- Purity
- 95%
- Packaging
- 5g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- MT-16633
- Product name
- 2-Mercaptothiazole
- Purity
- 98%
- Packaging
- 25g
- Price
- $256
- Updated
- 2021/12/16
2-Mercaptothiazole Chemical Properties,Usage,Production
Uses
2-Mercaptothiazole (Thiazoline-2-thione) is a thiazole compound that can be used as a basic structural unit in organic synthesis and is widely used in the pharmaceutical and chemical areas.
Synthesis
107-20-0
513-74-6
5685-05-2
The general procedure for the synthesis of thiazole-2(3H)-thione from chloroacetaldehyde and ammonium dithiocarbamate was as follows: a 40% solution of chloroacetaldehyde (0.61 mol) was slowly added to 100 mL of water, keeping the reaction temperature below 5 °C. Subsequently, 67 g of ammonium dithiocarbamate (0.61 mol) was added in batches. After the addition was completed, the reaction mixture was gradually warmed up to room temperature and stirred continuously for 2 h to promote complete reaction. A white solid precipitated during the reaction and the product was collected by filtration. The resulting filter cake was washed sequentially with a small amount of ethanol and cold water to remove impurities. Finally, the product was dried to give 66.2 g of white solid thiazole-2(3H)-thione in 93% yield.
References
[1] Patent: TWI609015, 2017, B. Location in patent: Paragraph 0190