ChemicalBook > CAS DataBase List > 2,4-Dichlorothiazole

2,4-Dichlorothiazole

Product Name
2,4-Dichlorothiazole
CAS No.
4175-76-2
Chemical Name
2,4-Dichlorothiazole
Synonyms
2,4-DICHLOROTHIAZOLE;2,4-Dichlorothiazole>Thiazole, 2,4-dichloro-;2,4-DICHLORO-1,3-THIAZOLE;2,4-Dichlorothiazole ,98%;2,4-Dichloro-1,3-thiazole 96%;2,4-Dichlorothiazole(WX636073);2,4-DICHLOROTHIAZOLE,98.0+%(GC)
CBNumber
CB1512175
Molecular Formula
C3HCl2NS
Formula Weight
154.02
MOL File
4175-76-2.mol
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2,4-Dichlorothiazole Property

Melting point:
44 °C
Boiling point:
184 °C
Density 
1.603±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
-1.93±0.10(Predicted)
color 
White to Light yellow to Light orange
InChIKey
ICETWLGKJXCIDX-UHFFFAOYSA-N
CAS DataBase Reference
4175-76-2(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
KOB0068
Product name
2,4-Dichloro-1,3-thiazole
Packaging
1g
Price
$179
Updated
2025/07/31
TCI Chemical
Product number
D3549
Product name
2,4-Dichlorothiazole
Purity
>98.0%(GC)
Packaging
5g
Price
$74
Updated
2025/07/31
TCI Chemical
Product number
D3549
Product name
2,4-Dichlorothiazole
Purity
>98.0%(GC)
Packaging
25g
Price
$220
Updated
2025/07/31
TRC
Product number
D436468
Product name
2,4-Dichlorothiazole
Packaging
10mg
Price
$45
Updated
2021/12/16
Ark Pharm
Product number
P000131695
Product name
2,4-Dichlorothiazole
Purity
97%
Packaging
250mg
Price
$5
Updated
2021/12/16
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2,4-Dichlorothiazole Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

2295-31-0

4175-76-2

The general procedure for the synthesis of 2,4-dichlorothiazole from 2,4-thiazolidinedione was as follows: 2,4-thiazolidinedione (50 g, 0.43 mol) was dissolved in phosphorus trichloride (240 mL) and cooled to 5 °C. Pyridine (34 mL, 0.43 mol) was added slowly over 15 minutes. The reaction mixture was heated to 125°C and maintained at this temperature for 4 hours. After completion of the reaction, it was cooled to 22°C. Excess phosphorus trichloride was removed by vacuum distillation. The residue was slowly poured into water (1 L) pre-cooled to 5°C. The aqueous phase was extracted with dichloromethane (3 x 400mL). The organic phases were combined and the solvents were evaporated to give the target product 2,4-dichlorothiazole (50 g, 76% yield).EI/MS m/z: (35Cl35Cl/35Cl37Cl/37Cl37Cl)153/155/157(M+1)+.

References

[1] Patent: WO2008/36579, 2008, A1. Location in patent: Page/Page column 36-37
[2] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 60
[3] Journal of the American Chemical Society, 2013, vol. 135, # 5, p. 1986 - 1996
[4] Patent: WO2013/149362, 2013, A1. Location in patent: Page/Page column 55
[5] Patent: WO2017/155909, 2017, A1. Location in patent: Paragraph 0159

2,4-Dichlorothiazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Dichlorothiazole Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
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China
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Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
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21-57721279
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QQ:14057904
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sales@shydchem.com.cn
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
Country
United States
ProdList
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
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59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
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64
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View Lastest Price from 2,4-Dichlorothiazole manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2,4-Dichlorothiazole 4175-76-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Career Henan Chemical Co
Product
2,4-Dichlorothiazole 4175-76-2
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
customise
Release date
2018-08-09