2,4-Dichlorothiazole
- Product Name
- 2,4-Dichlorothiazole
- CAS No.
- 4175-76-2
- Chemical Name
- 2,4-Dichlorothiazole
- Synonyms
- 2,4-DICHLOROTHIAZOLE;2,4-Dichlorothiazole>Thiazole, 2,4-dichloro-;2,4-DICHLORO-1,3-THIAZOLE;2,4-Dichlorothiazole ,98%;2,4-Dichloro-1,3-thiazole 96%;2,4-Dichlorothiazole(WX636073);2,4-DICHLOROTHIAZOLE,98.0+%(GC)
- CBNumber
- CB1512175
- Molecular Formula
- C3HCl2NS
- Formula Weight
- 154.02
- MOL File
- 4175-76-2.mol
2,4-Dichlorothiazole Property
- Melting point:
- 44 °C
- Boiling point:
- 184 °C
- Density
- 1.603±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- -1.93±0.10(Predicted)
- color
- White to Light yellow to Light orange
- InChIKey
- ICETWLGKJXCIDX-UHFFFAOYSA-N
- CAS DataBase Reference
- 4175-76-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- KOB0068
- Product name
- 2,4-Dichloro-1,3-thiazole
- Packaging
- 1g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- D3549
- Product name
- 2,4-Dichlorothiazole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $74
- Updated
- 2025/07/31
- Product number
- D3549
- Product name
- 2,4-Dichlorothiazole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $220
- Updated
- 2025/07/31
- Product number
- D436468
- Product name
- 2,4-Dichlorothiazole
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P000131695
- Product name
- 2,4-Dichlorothiazole
- Purity
- 97%
- Packaging
- 250mg
- Price
- $5
- Updated
- 2021/12/16
2,4-Dichlorothiazole Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
2295-31-0
4175-76-2
The general procedure for the synthesis of 2,4-dichlorothiazole from 2,4-thiazolidinedione was as follows: 2,4-thiazolidinedione (50 g, 0.43 mol) was dissolved in phosphorus trichloride (240 mL) and cooled to 5 °C. Pyridine (34 mL, 0.43 mol) was added slowly over 15 minutes. The reaction mixture was heated to 125°C and maintained at this temperature for 4 hours. After completion of the reaction, it was cooled to 22°C. Excess phosphorus trichloride was removed by vacuum distillation. The residue was slowly poured into water (1 L) pre-cooled to 5°C. The aqueous phase was extracted with dichloromethane (3 x 400mL). The organic phases were combined and the solvents were evaporated to give the target product 2,4-dichlorothiazole (50 g, 76% yield).EI/MS m/z: (35Cl35Cl/35Cl37Cl/37Cl37Cl)153/155/157(M+1)+.
References
[1] Patent: WO2008/36579, 2008, A1. Location in patent: Page/Page column 36-37
[2] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 60
[3] Journal of the American Chemical Society, 2013, vol. 135, # 5, p. 1986 - 1996
[4] Patent: WO2013/149362, 2013, A1. Location in patent: Page/Page column 55
[5] Patent: WO2017/155909, 2017, A1. Location in patent: Paragraph 0159
2,4-Dichlorothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-Dichlorothiazole Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 2,4-Dichlorothiazole manufacturers
- Product
- 2,4-Dichlorothiazole 4175-76-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 2,4-Dichlorothiazole 4175-76-2
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-09