4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one

Product Name: 4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one
CAS No.: 1095051-79-8
Chemical Name: 4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one
Synonyms: 2(3H)-Thiazolone, 4-(2-fluorophenyl)-;4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one;4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one, 10 mM in DMSO;4(2fluorophenyl)2,3dihydro1,3thiazol2one,4 (2 fluorophenyl) 2,3 dihydro 1,3 thiazol 2 one
CBNumber: CB15572880
Molecular Formula: C9H6FNOS
Formula Weight: 195.21
MOL File: 1095051-79-8.mol

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4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one Property

Density: 1.390±0.06 g/cm3(Predicted)
pka: 8.28±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B436505
Product name: 4-(2-Fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one
Packaging: 250mg
Price: $310
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0053599
Product name: 4-(2-FLUOROPHENYL)-2,3-DIHYDRO-1,3-THIAZOL-2-ONE
Purity: 95.00%
Packaging: 1G
Price: $852.55
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0053599
Product name: 4-(2-FLUOROPHENYL)-2,3-DIHYDRO-1,3-THIAZOL-2-ONE
Purity: 95.00%
Packaging: 2.5G
Price: $1227.82
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0053599
Product name: 4-(2-FLUOROPHENYL)-2,3-DIHYDRO-1,3-THIAZOL-2-ONE
Purity: 95.00%
Packaging: 5G
Price: $1548.26
Updated: 2021/12/16

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4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one Chemical Properties,Usage,Production

Uses

BRD4 Inhibitor-37 is a compound with anticancer activity that has inhibitory activity against BRD4. BRD4 Inhibitor-37 has an IC50 of approximately 0.05-0.1 μM in binding assays and shows a GI50 of 0.1-0.3 μM in cell-based assays. The effect of BRD4 Inhibitor-37 on c-Myc, a downstream protein of BRD4, has been validated, demonstrating its ability to intervene in this signaling pathway. BRD4 Inhibitor-37 exhibits selectivity among five different bromodomain proteins, enhancing its potential as a BET protein inhibitor[1].

References

[1] Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization

4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one Suppliers

CHINA 10 United States 2 Global 12

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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1095051-79-8, 4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-oneRelated Search:

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4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one

2(3H)-Thiazolone, 4-(2-fluorophenyl)-

4(2fluorophenyl)2,3dihydro1,3thiazol2one,4 (2 fluorophenyl) 2,3 dihydro 1,3 thiazol 2 one

4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one, 10 mM in DMSO

1095051-79-8