Applications Immunogen Background

KIR2DL3 Antibody

Applications Immunogen Background
Product Name
KIR2DL3 Antibody
Chemical Name
KIR2DL3 Antibody
Synonyms
KIR2DL3 Antibody;Rabbit Polyclonal KIR2DL3 Antibody
CBNumber
CB15649793
Formula Weight
0
MOL File
Mol file
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

KIR2DL3 Antibody Chemical Properties,Usage,Production

Applications

KIR2DL3 antibody has been tested by ELISA and Western blot immunofluorescent staining with flow cytometric analysis to assure specificity. Applications include flow cytometry (5-10g/1×1000000), ELISA (1:1,000 when tested against the immunized protein) an

Immunogen

Anti-human KIR2DL3 mAb, is derived from hybridization of mouse P3-x63-Ag8.653 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KIR2DL3 amino acids 19-161 purified from E. coli.

Background

Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. The KIR genes are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM). Whereas KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. KIR2DL3 is an inhibitory Killer Cell Ig-like Receptor (KIR, previously called p58 KIR, cl-6, NKAT2 or KIR-K7), which recognizes class I MHC molecules (HLA-Cw1, -Cw3, -Cw7, and Cw8). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.

KIR2DL3 Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

KIR2DL3 Antibody Suppliers

CHINA 44 Global 44
Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Hubei Ipodix Biotechnology Co.,Ltd.
Tel
18007124176 19384116026
Email
2706668885@qq.com
Country
China
ProdList
4987
Advantage
58
CUSABIO TECHNOLOGY LLC
Tel
027-87196173
Email
cusabio@163.com
Country
China
ProdList
6066
Advantage
58
Hubei Serenity BioSolutions Co., Ltd.
Tel
027-19371278702 18008634902
Email
19384116026@163.com
Country
China
ProdList
3008
Advantage
58
GeneTex, Inc.
Tel
0755-26755892 1-949-553-1900
Email
international@genetex.com
Country
China
ProdList
6092
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Biosynth Ltd
Tel
18886812933
Email
sales@biosynth.com
Country
China
ProdList
6218
Advantage
58
Abmart Inc
Tel
4006-123-828 13162017139
Email
market@ab-mart.com
Country
China
ProdList
6917
Advantage
58
Wuhan Fine Biotech Co Ltd
Tel
13047170542
Email
marketing@fn-test.com
Country
China
ProdList
6600
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
ProSpec Tany TechnoGene Ltd
Tel
972-8947-1175
Email
info@prospecbio.com
Country
China
ProdList
6874
Advantage
58
Rockland Immunochemicals Inc
Tel
0512-65829739
Email
antibodies-onlinename@qq.com
Country
China
ProdList
0
Advantage
58
Guangzhou Dianli Biotechnology Co., Ltd.
Tel
13022063134
Country
CHINA
ProdList
178
Advantage
58
Guangzhou Chuangze Biotechnology Co., Ltd.
Tel
18312220236
Country
CHINA
ProdList
178
Advantage
58
Chongqing Aowei Biotechnology Co., Ltd.
Tel
15223081335
Country
CHINA
ProdList
117
Advantage
58
Biorbyt Ltd.
Tel
--
Fax
--
Email
info@biorbyt.com
Country
CHINA
ProdList
6482
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6448
Advantage
58
Beijing Bomais Technology Development Co., Ltd.
Tel
--
Fax
--
Email
15210716102@139.com
Country
CHINA
ProdList
6274
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Nanjing Laifusai Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@lifescimall.com
Country
CHINA
ProdList
6638
Advantage
58
Shanghai Fushen Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
jsyz216@163.com
Country
CHINA
ProdList
6547
Advantage
58
Shanghai Qingmu Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6826
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6525
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6170
Advantage
58
Changzhou Xiangtai Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
order@affbiotech.com
Country
CHINA
ProdList
6801
Advantage
58
Shanghai Yubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
shybio@126.com
Country
CHINA
ProdList
6966
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Beijing Dakco is Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
bj_info@dakewe.net
Country
CHINA
ProdList
6580
Advantage
58
Shanghai Guandao Biological Engineering Co., Ltd.
Tel
--
Fax
--
Email
3307204271@qq.com
Country
CHINA
ProdList
6390
Advantage
58
Beijing Bai Ao Si Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
yangmei@bioneeds.net
Country
CHINA
ProdList
6999
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Lianshuobao is Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
lianshuobio@163.com
Country
CHINA
ProdList
6984
Advantage
58
Beijing Jiamei Zhenyuan Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6403
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58
Beijing Baiao Innovation Technology Co., Ltd.
Tel
--
Fax
--
Email
3007606172@qq.com
Country
CHINA
ProdList
6002
Advantage
58
Shanghai Huzhen Industrial Co., Ltd.
Tel
--
Fax
--
Email
shhzsw01@163.com
Country
CHINA
ProdList
6477
Advantage
58
Wuhan Boot Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6829
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6646
Advantage
58
Bsno (Tianjin) Biotechnology Co., Ltd
Tel
--
Fax
--
Email
1073531646@qq.com
Country
CHINA
ProdList
6571
Advantage
58
Shanghai Yuqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
847627550@qq.com
Country
CHINA
ProdList
6087
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58

KIR2DL3 AntibodyRelated Search:

TCOF1 antibody Rabbit Polyclonal WDR36 Antibody ATP6V0A1 Antibody DPY30 antibody ZNF397 antibody MRPL20 antibody FGF21 antibody FRK antibody SEMA6D antibody ASB3 antibody

  • KIR2DL3 Antibody
  • Rabbit Polyclonal KIR2DL3 Antibody