PDLIM2 antibody
Source Reactivity Background References- Product Name
- PDLIM2 antibody
- Chemical Name
- PDLIM2 antibody
- Synonyms
- PDLIM2 antibody
- CBNumber
- CB15671286
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb312720
- Product name
- PDLIM2 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb312720
- Product name
- PDLIM2 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
PDLIM2 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse
Background
PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration. Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65. PDLIM2 is suppressed in cancer cell lines by DNA methylation. Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation.
References
[1] Torrado, M. et al. (2004) Invest Ophthalmol Vis Sci 45, 3955-63.
[2] Loughran, G. et al. (2005) Mol Biol Cell 16, 1811-22.
[3] Tanaka, T. et al. (2007) Nat Immunol 8, 584-91.
[4] Qu, Z. et al. (2010) Cancer Res 70, 1766-1772.
[5] Qu, Z. et al. (2010) J Biol Chem 285, 11786-92.
PDLIM2 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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