Biotin-PEG3-SH
- Product Name
- Biotin-PEG3-SH
- CAS No.
- 1244028-52-1
- Chemical Name
- Biotin-PEG3-SH
- Synonyms
- Biotin-PEG3-SH;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]ethyl]-2-oxo-, (3aS,4S,6aR)-;5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-{2-[2-(2-sulfanylethoxy)ethoxy]ethoxy}ethyl)pentanamide
- CBNumber
- CB16183960
- Molecular Formula
- C18H33N3O5S2
- Formula Weight
- 435.6
- MOL File
- 1244028-52-1.mol
Biotin-PEG3-SH Property
- Boiling point:
- 716.4±60.0 °C(Predicted)
- Density
- 1.179±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, sealed storage, away from moisture
- pka
- 9+-.0.10(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- LS-4260
- Product name
- Biotin-PEG(3)-SH
- Packaging
- 250mg
- Price
- $1890
- Updated
- 2021/12/16
Biotin-PEG3-SH Chemical Properties,Usage,Production
Uses
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Biotin-PEG3-SH Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-PEG3-SH Suppliers
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15781
- Advantage
- 55
- Tel
- 027-65563561
- Fax
- 86-27-59218822
- sales@borenpharm.com
- Country
- China
- ProdList
- 1245
- Advantage
- 55
- Tel
- 027-65563561 18717150066
- Fax
- 027-59218822
- 3207347307@qq.com
- Country
- CHINA
- ProdList
- 1238
- Advantage
- 58
- Tel
- 18191076804
- asherw9@hotmail.com
- Country
- China
- ProdList
- 2373
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 54995
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 18616385138
- Fax
- 400-618-1121
- sales@townyuan.com
- Country
- China
- ProdList
- 2696
- Advantage
- 58
- Tel
- 13356310019 13356310019;
- boyu2024@163.com
- Country
- China
- ProdList
- 3992
- Advantage
- 58
- Tel
- 17721070236 15002190549;
- yanfen2023@126.com
- Country
- China
- ProdList
- 1793
- Advantage
- 58