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NARIRUTIN

Product Name
NARIRUTIN
CAS No.
14259-46-2
Chemical Name
NARIRUTIN
Synonyms
NARINGENIN-7-O-RUTINOSIDE;ISONARINGIN;Isonaringenin;NARINGENIN-7-RUTINOSIDE;rirutin;NARIRUTIN;Aids089292;Aids-089292;NARIRUTIN(P);Narirutin-RM
CBNumber
CB1665574
Molecular Formula
C27H32O14
Formula Weight
580.53
MOL File
14259-46-2.mol
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NARIRUTIN Property

Melting point:
162-164°C
Boiling point:
924.3±65.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
FEMA 
2769 | NARINGEN EXTRACT (CITRUS PARADISI MACF.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
form 
Solid
pka
7.18±0.40(Predicted)
color 
Pale Yellow
Odor
bland
InChIKey
HXTFHSYLYXVTHC-MSTHVRLMSA-N
SMILES
C1C(O[C@@H]2OC(CO[C@@H]3OC(C)[C@H](O)[C@H](O)C3O)[C@@H](O)[C@@H](O)C2O)=CC2OC(C3C=CC(O)=CC=3)CC(=O)C=2C=1O
LogP
2.07
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Safety

Safety Statements 
22-24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00321
Product name
Narirutin
Purity
≥98% (HPLC)
Packaging
10 mg
Price
$392
Updated
2025/07/31
TCI Chemical
Product number
N1125
Product name
Narirutin
Packaging
25MG
Price
$220
Updated
2025/07/31
Cayman Chemical
Product number
25124
Product name
Narirutin
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
25124
Product name
Narirutin
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
25124
Product name
Narirutin
Purity
≥98%
Packaging
25mg
Price
$379
Updated
2024/03/01
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NARIRUTIN Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

(2S)-Narirutin is a naturally occurring flavonoid that possess anti-allergic, anti-inflammatory, antiproliferative and anti-oxidant properties.

Definition

ChEBI: A disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a lycosidic linkage.

Biological Activity

Narirutin is known to possess anti-allergic, anti-inflammatory, antioxidant, and anti-proliferative properties. It inhibits allergic eosinophilic airway inflammation in the mouse model. Narirutin also inhibits lipopolysaccharide (LPS)-induced inflammatory response by inhibiting nuclear factor-KB (NF-KB) and mitogen-activated protein kinases (MAPKs). It displays antioxidant and protective effects on attenuating alcohol-induced liver damage while co-consumed with alcohol in mice model, and can be useful in Alzheimerμs disease (AD) therapeutics.

in vivo

Narirutin (10 mg/kg, p.o ) reduces eosinophil counts in peripheral blood in OVA-challenged mice[2].
Narirutin (10 mg/kg, p.o ) block the OVA-induced increase in IL-4 but has no effect on the increase in IL-5[2].

Animal Model:Allergic asthma female NC/Nga mice model[2]
Dosage: 0.1, 1 or 10 mg/kg
Administration:Orally, 7d
Result:Reduced eosinophil counts in peripheral blood.
Blocked the OVA-induced increase in IL-4.

NARIRUTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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NARIRUTIN Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from NARIRUTIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Narirutin 14259-46-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Yanxi Chemical Co., Ltd.
Product
Narirutin 14259-46-2
Price
US $100.00/kgkg
Min. Order
1kgkg
Purity
0.99
Supply Ability
100
Release date
2023-09-20
Shanghai Standard Technology Co., Ltd.
Product
Narirutin 14259-46-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-15

14259-46-2, NARIRUTINRelated Search:


  • NARIRUTIN
  • NARINGENIN-7-RUTINOSIDE
  • NARINGENIN-7-O-RUTINOSIDE
  • ISONARINGIN
  • (S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 7-6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyloxy-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • NARIRUTIN hplc
  • NARIRUTIN WITH HPLC
  • (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2α-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Isonaringenin
  • 5-Hydroxy-2-(4-hydroxy-phenyl)-7-[3,4,5-trihydroxy-6-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-1-benzopyran-4-one
  • Aids089292
  • Aids-089292
  • NARIRUTIN(P)
  • NARIRUTIN(RG)
  • (2S)-Narirutin
  • Narirutin, froM Citrus MaxiMa
  • NARINGEN EXTRACT (CITRUS PARADISI MACF.)
  • Narirutin, 98%, from Citrus maxima (Burm.) Merr.
  • Diosmin Impurity 21 (Narirutin)
  • Narirutin Standard
  • (S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
  • (S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosy...
  • NarirutinQ: What is Narirutin Q: What is the CAS Number of Narirutin Q: What is the storage condition of Narirutin Q: What are the applications of Narirutin
  • (S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
  • Narirutin (8CI)
  • Naringenin impurities1
  • Narirutin-RM
  • rirutin
  • 14259-46-2
  • Flavanones
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract