NARIRUTIN
- Product Name
- NARIRUTIN
- CAS No.
- 14259-46-2
- Chemical Name
- NARIRUTIN
- Synonyms
- NARINGENIN-7-O-RUTINOSIDE;ISONARINGIN;Isonaringenin;NARINGENIN-7-RUTINOSIDE;rirutin;NARIRUTIN;Aids089292;Aids-089292;NARIRUTIN(P);Narirutin-RM
- CBNumber
- CB1665574
- Molecular Formula
- C27H32O14
- Formula Weight
- 580.53
- MOL File
- 14259-46-2.mol
NARIRUTIN Property
- Melting point:
- 162-164°C
- Boiling point:
- 924.3±65.0 °C(Predicted)
- Density
- 1.66±0.1 g/cm3(Predicted)
- FEMA
- 2769 | NARINGEN EXTRACT (CITRUS PARADISI MACF.)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 7.18±0.40(Predicted)
- color
- Pale Yellow
- Odor
- bland
- InChIKey
- HXTFHSYLYXVTHC-MSTHVRLMSA-N
- SMILES
- C1C(O[C@@H]2OC(CO[C@@H]3OC(C)[C@H](O)[C@H](O)C3O)[C@@H](O)[C@@H](O)C2O)=CC2OC(C3C=CC(O)=CC=3)CC(=O)C=2C=1O
- LogP
- 2.07
Safety
- Safety Statements
- 22-24/25
- HS Code
- 29389090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SMB00321
- Product name
- Narirutin
- Purity
- ≥98% (HPLC)
- Packaging
- 10 mg
- Price
- $392
- Updated
- 2025/07/31
- Product number
- N1125
- Product name
- Narirutin
- Packaging
- 25MG
- Price
- $220
- Updated
- 2025/07/31
- Product number
- 25124
- Product name
- Narirutin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 25124
- Product name
- Narirutin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 25124
- Product name
- Narirutin
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $379
- Updated
- 2024/03/01
NARIRUTIN Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
(2S)-Narirutin is a naturally occurring flavonoid that possess anti-allergic, anti-inflammatory, antiproliferative and anti-oxidant properties.
Definition
ChEBI: A disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a lycosidic linkage.
Biological Activity
Narirutin is known to possess anti-allergic, anti-inflammatory, antioxidant, and anti-proliferative properties. It inhibits allergic eosinophilic airway inflammation in the mouse model. Narirutin also inhibits lipopolysaccharide (LPS)-induced inflammatory response by inhibiting nuclear factor-KB (NF-KB) and mitogen-activated protein kinases (MAPKs). It displays antioxidant and protective effects on attenuating alcohol-induced liver damage while co-consumed with alcohol in mice model, and can be useful in Alzheimerμs disease (AD) therapeutics.
in vivo
Narirutin (10 mg/kg, p.o ) reduces eosinophil counts in peripheral blood in OVA-challenged mice[2].
Narirutin (10 mg/kg, p.o ) block the OVA-induced increase in IL-4 but has no effect on the increase in IL-5[2].
| Animal Model: | Allergic asthma female NC/Nga mice model[2] |
| Dosage: | 0.1, 1 or 10 mg/kg |
| Administration: | Orally, 7d |
| Result: | Reduced eosinophil counts in peripheral blood. Blocked the OVA-induced increase in IL-4. |
NARIRUTIN Preparation Products And Raw materials
Raw materials
Preparation Products
NARIRUTIN Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from NARIRUTIN manufacturers
- Product
- Narirutin 14259-46-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- Narirutin 14259-46-2
- Price
- US $100.00/kgkg
- Min. Order
- 1kgkg
- Purity
- 0.99
- Supply Ability
- 100
- Release date
- 2023-09-20
- Product
- Narirutin 14259-46-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-15