ChemicalBook > CAS DataBase List > NARIRUTIN

NARIRUTIN

Product Name: NARIRUTIN
CAS No.: 14259-46-2
Chemical Name: NARIRUTIN
Synonyms: NARINGENIN-7-O-RUTINOSIDE;ISONARINGIN;Isonaringenin;NARINGENIN-7-RUTINOSIDE;rirutin;NARIRUTIN;Aids089292;Aids-089292;NARIRUTIN(P);Narirutin-RM
CBNumber: CB1665574
Molecular Formula: C27H32O14
Formula Weight: 580.53
MOL File: 14259-46-2.mol

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NARIRUTIN Property

Melting point:: 162-164°C
Boiling point:: 924.3±65.0 °C(Predicted)
Density: 1.66±0.1 g/cm3(Predicted)
FEMA: 2769 | NARINGEN EXTRACT (CITRUS PARADISI MACF.)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
form: Solid
pka: 7.18±0.40(Predicted)
color: Pale Yellow
Odor: bland
InChIKey: HXTFHSYLYXVTHC-MSTHVRLMSA-N
SMILES: C1C(O[C@@H]2OC(CO[C@@H]3OC(C)[C@H](O)[C@H](O)C3O)[C@@H](O)[C@@H](O)C2O)=CC2OC(C3C=CC(O)=CC=3)CC(=O)C=2C=1O
LogP: 2.07

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Safety

Safety Statements: 22-24/25
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00321
Product name: Narirutin
Purity: ≥98% (HPLC)
Packaging: 10 mg
Price: $392
Updated: 2025/07/31

TCI Chemical

Product number: N1125
Product name: Narirutin
Packaging: 25MG
Price: $220
Updated: 2025/07/31

Cayman Chemical

Product number: 25124
Product name: Narirutin
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 25124
Product name: Narirutin
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 25124
Product name: Narirutin
Purity: ≥98%
Packaging: 25mg
Price: $379
Updated: 2024/03/01

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NARIRUTIN Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

(2S)-Narirutin is a naturally occurring flavonoid that possess anti-allergic, anti-inflammatory, antiproliferative and anti-oxidant properties.

Definition

ChEBI: A disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a lycosidic linkage.

Biological Activity

Narirutin is known to possess anti-allergic, anti-inflammatory, antioxidant, and anti-proliferative properties. It inhibits allergic eosinophilic airway inflammation in the mouse model. Narirutin also inhibits lipopolysaccharide (LPS)-induced inflammatory response by inhibiting nuclear factor-KB (NF-KB) and mitogen-activated protein kinases (MAPKs). It displays antioxidant and protective effects on attenuating alcohol-induced liver damage while co-consumed with alcohol in mice model, and can be useful in Alzheimerμs disease (AD) therapeutics.

in vivo

Narirutin (10 mg/kg, p.o ) reduces eosinophil counts in peripheral blood in OVA-challenged mice^[2].
Narirutin (10 mg/kg, p.o ) block the OVA-induced increase in IL-4 but has no effect on the increase in IL-5^[2].

Animal Model:	Allergic asthma female NC/Nga mice model^[2]
Dosage:	0.1, 1 or 10 mg/kg
Administration:	Orally, 7d
Result:	Reduced eosinophil counts in peripheral blood. Blocked the OVA-induced increase in IL-4.

NARIRUTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NARIRUTIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Narirutin 14259-46-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

Hebei Yanxi Chemical Co., Ltd.

Product: Narirutin 14259-46-2
Price: US $100.00/kgkg
Min. Order: 1kgkg
Purity: 0.99
Supply Ability: 100
Release date: 2023-09-20

Shanghai Standard Technology Co., Ltd.

Product: Narirutin 14259-46-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-15

14259-46-2, NARIRUTINRelated Search:

Hesperidin NARINGIN HYDRATE TECH. Rutin BRASSININ Brassinolide RUTINOSE RUTIN HYDRATE 95 TEREBIC ACID 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)- Ethyl rutinoside 1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE 4-N-BUTOXYBENZALDEHYDE 4-(2-Hydroxyethoxy)benzaldehyde NARIRUTIN Ethylene Glycol Dibutyl Ether Methyl hesperidin Raspberry Ketone Naringenin

NARIRUTIN

NARINGENIN-7-RUTINOSIDE

NARINGENIN-7-O-RUTINOSIDE

ISONARINGIN

(S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 7-6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyloxy-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-

NARIRUTIN hplc

NARIRUTIN WITH HPLC

(2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2α-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Isonaringenin

5-Hydroxy-2-(4-hydroxy-phenyl)-7-[3,4,5-trihydroxy-6-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-1-benzopyran-4-one

Aids089292

Aids-089292

NARIRUTIN(P)

NARIRUTIN(RG)

(2S)-Narirutin

Narirutin, froM Citrus MaxiMa

NARINGEN EXTRACT (CITRUS PARADISI MACF.)

Narirutin, 98%, from Citrus maxima (Burm.) Merr.

Diosmin Impurity 21 (Narirutin)

Narirutin Standard

(S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-

4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-

(2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one

(S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosy...

NarirutinQ: What is Narirutin Q: What is the CAS Number of Narirutin Q: What is the storage condition of Narirutin Q: What are the applications of Narirutin

(S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one

Narirutin (8CI)

Naringenin impurities1

Narirutin-RM

rirutin

14259-46-2

Flavanones

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract