3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE

Product Name: 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
CAS No.: 380238-10-8
Chemical Name: 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
Synonyms: AKOS BBS-00006677;5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine;3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE;5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE;1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-;5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride
CBNumber: CB1667679
Molecular Formula: C11H10F3N3
Formula Weight: 241.21
MOL File: Mol file

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3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Property

Boiling point:: 342.7±42.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 3.37±0.10(Predicted)
form: powder
color: Off-white

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Safety

HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M332168
Product name: 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1h-pyrazol-5-amine
Packaging: 250mg
Price: $305
Updated: 2021/12/16

Apolloscientific

Product number: PC400534
Product name: 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Packaging: 250mg
Price: $101
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-3-1R
Product name: 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Packaging: 250mg
Price: $111
Updated: 2021/12/16

AK Scientific

Product number: 2021AE
Product name: 3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine
Packaging: 250mg
Price: $178
Updated: 2021/12/16

Apolloscientific

Product number: PC400534
Product name: 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Packaging: 1g
Price: $221
Updated: 2021/12/16

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3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Chemical Properties,Usage,Production

Synthesis

1118-61-2

365-34-4

380238-10-8

GENERAL METHOD: 3-Aminobut-2-enenenitrile (10 mmol) was added to a suspension of (2-(trifluoromethyl)phenyl)hydrazine (10 mmol) in 12 M HCl-H2O (12 mL, 1:3 v/v). The reaction mixture was heated to reflux for 12 h, subsequently cooled to room temperature and neutralized with 2.5 M NaOH solution. The reaction mixture was extracted with dichloromethane (3 x 30 mL). The organic phases were combined, washed with saturated saline (20 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was ground with hexane to give a solid product, which was separated by filtration. If necessary, the product was purified by column chromatography.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 11, p. 3429 - 3445
[2] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 136-137
[3] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 510 - 517

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Suppliers

China 24 Germany 1 India 1 Ukraine 3 United Kingdom 1 United States 5 Global 35

Chem-Stone Co.,Ltd.

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career henan chemical co

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Energy Chemical

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View Lastest Price from 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE manufacturers

Career Henan Chemical Co

Product: 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2020-01-10

380238-10-8, 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINERelated Search:

5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE

AKOS BBS-00006677

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE

5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride

1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-

5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine

380238-10-8