ChemicalBook > CAS DataBase List > 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE

Product Name
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
CAS No.
380238-10-8
Chemical Name
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
Synonyms
AKOS BBS-00006677;5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine;3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE;5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE;1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-;5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride
CBNumber
CB1667679
Molecular Formula
C11H10F3N3
Formula Weight
241.21
MOL File
Mol file
More
Less

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Property

Boiling point:
342.7±42.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
3.37±0.10(Predicted)
form 
powder
color 
Off-white
More
Less

Safety

HS Code 
2933199090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
M332168
Product name
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1h-pyrazol-5-amine
Packaging
250mg
Price
$305
Updated
2021/12/16
Matrix Scientific
Product number
101930
Product name
3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine
Purity
95%
Packaging
1g
Price
$357
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-3-1R
Product name
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Packaging
1g
Price
$244
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0054282
Product name
5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE
Purity
95.00%
Packaging
1G
Price
$910.76
Updated
2021/12/16
Matrix Scientific
Product number
101930
Product name
3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine
Purity
95%
Packaging
5g
Price
$983
Updated
2021/12/16
More
Less

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Chemical Properties,Usage,Production

Synthesis

1118-61-2

365-34-4

380238-10-8

GENERAL METHOD: 3-Aminobut-2-enenenitrile (10 mmol) was added to a suspension of (2-(trifluoromethyl)phenyl)hydrazine (10 mmol) in 12 M HCl-H2O (12 mL, 1:3 v/v). The reaction mixture was heated to reflux for 12 h, subsequently cooled to room temperature and neutralized with 2.5 M NaOH solution. The reaction mixture was extracted with dichloromethane (3 x 30 mL). The organic phases were combined, washed with saturated saline (20 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was ground with hexane to give a solid product, which was separated by filtration. If necessary, the product was purified by column chromatography.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 11, p. 3429 - 3445
[2] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 136-137
[3] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 510 - 517

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE manufacturers

Career Henan Chemical Co
Product
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1ton
Release date
2020-01-10

380238-10-8, 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINERelated Search:


  • 5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE
  • AKOS BBS-00006677
  • 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
  • 5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride
  • 1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-
  • 5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine
  • 380238-10-8