ChemicalBook > CAS DataBase List > (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID

Product Name: (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
CAS No.: 5709-98-8
Chemical Name: (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
Synonyms: (R)-3-Cyclohexene-1-carboxylic acid;(R)-Cyclohex-3-enecarboxylic acid;EOS-61457;(R) -3-cyclohexenoic acid;(R)-3-cyclohexene-1-carboxylic;(R)-3-CyclohexenecarboxylicAci;(R)-cyclohex-3-ene-1-carboxylicacid;(R)-3-Cyclohexene-1β-carboxylic acid;(1R)-3-Cyclohexene-1-carboxylic acid;(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
CBNumber: CB1673391
Molecular Formula: C7H10O2
Formula Weight: 126.15
MOL File: 5709-98-8.mol

Less

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID Property

Boiling point:: 90 °C(Press: 0.2 Torr)
Density: 1.126±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform, Methanol
form: Oil
pka: 4.67±0.20(Predicted)
color: Colorless
optical activity: 127.898°(C=1g/100ml CHCL3)
InChI: InChI=1S/C7H10O2/c8-7(9)6-4-2-1-3-5-6/h1-2,6H,3-5H2,(H,8,9)/t6-/m0/s1
InChIKey: VUSWCWPCANWBFG-LURJTMIESA-N
SMILES: [C@@H]1(C(O)=O)CCC=CC1
CAS DataBase Reference: 5709-98-8

Less

Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN3265
HazardClass: 8
HS Code: 2916200090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H312Harmful in contact with skin

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: C987885
Product name: (R)-3-CyclohexenecarboxylicAcid
Packaging: 25mg
Price: $160
Updated: 2021/12/16

TRC

Product number: C987885
Product name: (R)-3-CyclohexenecarboxylicAcid
Packaging: 100mg
Price: $595
Updated: 2021/12/16

Matrix Scientific

Product number: 122285
Product name: (R)-(+)-3-Cyclohexenecarboxylicacid
Purity: 97.0%
Packaging: 1g
Price: $42
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2421-1-R0
Product name: (1R)-Cyclohex-3-ene-1-carboxylic acid
Purity: 97.0%
Packaging: 250mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20702
Product name: (R)-3-Cyclohexenecarboxylic acid
Packaging: 250mg
Price: $105
Updated: 2021/12/16

Less

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

Colorless Oil

Uses

An intermediate of Leustroducsin B (LSN-B), a novel colony-stimulating factor (CSF) inducer, which was isolated from Streptomyces platensis.

Synthesis

6493-77-2

5709-98-8

Synthesis of Intermediate IV: Porcine liver esterase (PLE, 51.2 mg, 1382 units) was added to a stirred suspension of methyl 3-cyclohexene-1-carboxylate (III, 5.19 g, 37.0 mmol) in pH 7.00 phosphate buffer solution (520 mL, 0.07 M). The pH of the reaction system was maintained at 7.00 by dropwise addition of NaOH solution (1.0 M) via syringe pump.The reaction was stirred continuously at room temperature until 1 equivalent of NaOH (37 mL) was consumed (reaction time: 11 h, TLC monitoring of the unfolding agent: petroleum ether/ether, 1:1). The reaction mixture was transferred to a dispensing funnel and washed twice with ethyl acetate (2 × 300 mL). After separating the phases, the organic phase was back-extracted twice with pH 7.00 phosphate buffer solution (2 × 300 mL). The aqueous phases were combined and acidified to pH 2 with aqueous HCl (30 mL, 4 M), followed by three extractions with ethyl acetate (3 × 400 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure (100 mbar). The crude product was filtered through a short silica gel column to afford (R)-3-cyclohexenecarboxylic acid (IV) as a light yellow oil (3.92 g, 84% yield). The enantiomeric excess values of the product were 96.3% ee (GC assay), 94.3% ee (spin assay), [α]D21 +89.12° (c = 6.730, methanol) (literature value: +94.5° (c = 7, methanol), [Acta Chem. Scand., 1970, 24, 2693]).

References

[1] Patent: US2008/161546, 2008, A1. Location in patent: Page/Page column title page; 18
[2] Chemistry - A European Journal, 2012, vol. 18, # 5, p. 1342 - 1351
[3] Patent: US2008/200406, 2008, A1. Location in patent: Page/Page column 25; sheet 1
[4] Patent: US2011/251148, 2011, A1. Location in patent: Page/Page column 9
[5] Patent: WO2012/61662, 2012, A1. Location in patent: Page/Page column 60

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID Suppliers

Canada 1 China 174 India 3 United Kingdom 2 United States 15 Global 195

Sunyan Biotech (Heze) Co.,Ltd

Tel: 19256007915 19256007915
Email: 375811307@qq.com
Country: China
ProdList: 38
Advantage: 58

Zhengzhou Kangshan Biological Co., Ltd.

Tel: +86-0371-55023472 +86-13663848272
Fax: 0371-55023472
Email: 2584787837@qq.com
Country: China
ProdList: 260
Advantage: 58

ZhengZhou Yimi Pharma R&D Co.,LTD.

Tel: 15393710992
Email: 375000787@QQ.com
Country: China
ProdList: 21
Advantage: 58

Bayee Biotech (Anqing) Co., Ltd.

Tel: 0556-5032306 18917961636
Email: wtx@bayeebio.com
Country: China
ProdList: 239
Advantage: 61

Anhui heavy sky biological technology Co., LTD

Tel: 15556773118
Email: 3848575348@qq.com
Country: China
ProdList: 56
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 5178
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 0512-62857507
Fax: +86-512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 991
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai ACT chemical Limited

Tel: 021-59904146 18001826933
Fax: +86-21-59904146
Email: sales@actchemical.com
Country: China
ProdList: 476
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4641
Advantage: 60

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: 52513593@qq.com
Country: China
ProdList: 2331
Advantage: 50

Beijing Holiyang Chemical Co. Ltd.

Tel: 13718199399
Fax: QQ : 206661479
Email: holiyangchem@163.com
Country: China
ProdList: 3280
Advantage: 56

Shanghai YouPeng Chemical Co. Ltd.

Tel: 021-69005955 13701776567
Fax: 021-69005775
Email: youpengchem@163.com
Country: China
ProdList: 4161
Advantage: 56

Sichuan Hainuowei Technology Co. Ltd.

Tel: 13708085536 13708085536
Fax: QQ : 121102042
Email: hanovichem@163.com
Country: China
ProdList: 3282
Advantage: 56

Shanghai TongYuan Chemical Co., Ltd.

Tel: 021-021-69182866 13701855675
Fax: 021-69182022
Email: tongyuanchem@126.com
Country: China
ProdList: 4193
Advantage: 58

Shanghai Kaisai Chemical Co., Ltd

Tel: 021-33516722 13701817765
Fax: 021-33516776
Email: kaisaichem@163.com
Country: China
ProdList: 4610
Advantage: 58

Shanghai LanRun Chemical Co., Ltd.

Tel: 021-69515658 ; 69515628 13701998368
Fax: 021-69515998
Email: longrunchem@163.com
Country: China
ProdList: 3786
Advantage: 50

Shanghai Rolead Chemical Technology Co., Ltd.

Tel: 021-69992220 13701886816
Fax: 021-69992237
Email: roleadchem@163.com
Country: China
ProdList: 4613
Advantage: 50

Shanghai Kangtuo Chemical Co., Ltd.

Tel: 021-69185552 13701777608
Fax: 021-69186006
Email: kangtuochem@163.com
Country: China
ProdList: 4232
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Haimen Ruiyi Medical Tech Co., LTD

Tel: 021-54718086
Fax: 021-54711707
Email: sales5@ruiyitech.com
Country: China
ProdList: 271
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Shanghai XiZhi Chemical Co., Ltd.

Tel: 021-69005855 13701817869
Fax: 021-69005955
Email: xizhichem@163.com
Country: China
ProdList: 3339
Advantage: 55

Shanghai Pengsuo Biochemical Technology Co., Ltd.

Tel: 021-59118555 13701823997
Fax: 021-59119222
Email: pengsuochem@163.com
Country: China
ProdList: 3300
Advantage: 55

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 2267
Advantage: 55

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7218
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12475
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Jiangsu C-jun Biotechnology Co., Ltd.

Tel: +86 (519) 8969-7536
Fax: +86 (519) 8988-9226
Email: sales3@cjxrpharm.com
Country: China
ProdList: 217
Advantage: 58

Nanjing Nohon Biological Technology Co., Ltd.

Tel: 025-85767923 18512596075
Fax: 025-85767923
Email: sales@nuoxibio.com
Country: China
ProdList: 962
Advantage: 55

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2389
Advantage: 58

Zhengzhou JACS Chemical Co., Ltd.

Tel: 0371-0371-86259281 15981966935
Fax: 0371-86259281
Email: jacschem@163.com
Country: China
ProdList: 2005
Advantage: 58

Less

View Lastest Price from (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID 5709-98-8
Price: US $980.00-750.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-15

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-3-Cyclohexene-1-carboxylic acid 5709-98-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Zhengzhou Anbu Chem Co.,Ltd

Product: (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID 5709-98-8
Price: US $0.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2023-06-13

5709-98-8, (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACIDRelated Search:

4,10-DIOXATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE Methyl-5-norbornene-2,3-dicarboxylic anhydride TRANS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID CIS-4-CYCLOHEXENE-1,2-DICARBOXYLIC ACID 6-Methoxycarbonyl-3-cyclohexene-1-carboxylic acid EXO-3,6-EPOXY-1,2,3,6-TETRAHYDROPHTHALIC ANHYDRIDE 1,2,3,6-Tetrahydro-4-methylphthalic anhydride CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID Carbic anhydride MONO-METHYL CIS-5-NORBORNENE-ENDO-2,3-DICARBOXYLATE cis-1,2,3,6-Tetrahydrophthalic anhydride ENDO-BICYCLO[2.2.2]OCT-5-ENE-2,3-DICARBOXYLIC ANHYDRIDE 5-Norbornene-2,3-dicarboxylic acid (3R,4S,5R)-3,4,5-TRIHYDROXY-1-CYCLOHEXENECARBOXYLIC ACID 1-CYCLOHEXENECARBOXYLIC ACID (S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID 3-CYCLOHEXENECARBOXYLIC ACID,3-CYCLOHEXENECARBOXYLIC ACID,98%,delta3-Cyclohexenecarboxylic acid,delta(Sup3)-Cyclohexenecarboxylic acid ETHYL CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLATE HYDROCHLORIDE

(R)-(+)-1,2,3,6-Tetrahydrobenzoic acid

(1R)-cyclohex-3-ene-1-carboxylic acid

(R)-Cyclohex-3-enecarboxylic acid

(R)-cyclohex-3-ene-1-carboxylicacid

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID

(1R)-3-Cyclohexene-1-carboxylic acid

(R)-3-Cyclohexene-1-carboxylic acid

(R)-3-Cyclohexene-1β-carboxylic acid

EOS-61457

(R)-cyclohex-3-ene-1-carboxylicacidChemicalbook

3-Cyclohexene-1-carboxylic acid, (1R)-

(R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID ISO 9001：2015 REACH

(R)-3-cyclohexene-1-carboxylic

(R)-3-CyclohexenecarboxylicAci

(R) -3-cyclohexenoic acid

5709-98-8

5709-98-9

C7H102

Chiral Compound

Chiral Reagents