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DICLOFENAC-D4

Product Name
DICLOFENAC-D4
CAS No.
153466-65-0
Chemical Name
DICLOFENAC-D4
Synonyms
D4-Diclofenac;DICLOFENAC-D4;[2H4]-Diclofenac;Diclofenac-D4 (Major);DICLOFENAC-D4 (PHENYL-D4);2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid;Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
CBNumber
CB1677920
Molecular Formula
C14H11Cl2NO2
Formula Weight
296.15
MOL File
153466-65-0.mol
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DICLOFENAC-D4 Property

Melting point:
157-159°C
storage temp. 
-20°C Freezer
solubility 
DMSO: 35 mg/ml,Ethanol: 35 mg/ml,PBS (pH 7.2): 6 mg/ml
form 
A solid
color 
White to off-white
Water Solubility 
Water: 50 mg/ml
CAS DataBase Reference
153466-65-0
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
19072
Product name
Diclofenac-d4
Purity
≥99%
Packaging
500μg
Price
$135
Updated
2024/03/01
Cayman Chemical
Product number
19072
Product name
Diclofenac-d4
Purity
≥99%
Packaging
1mg
Price
$241
Updated
2024/03/01
TRC
Product number
D436452
Product name
Diclofenac-d4
Packaging
1mg
Price
$195
Updated
2021/12/16
TRC
Product number
D436452
Product name
Diclofenac-d4
Packaging
10mg
Price
$825
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD165151
Product name
Diclofenac-D4
Packaging
250ug
Price
$60
Updated
2021/12/16
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DICLOFENAC-D4 Chemical Properties,Usage,Production

Description

Diclofenac-d4 is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Chemical Properties

Off-White Crystalline Solid

Uses

Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2

Uses

Labelled Diclofenac is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.

Uses

Labelled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.

DICLOFENAC-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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DICLOFENAC-D4 Suppliers

Canada 4 CHINA 42 India 4 United Kingdom 1 United States 5 Global 56
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58

153466-65-0, DICLOFENAC-D4Related Search:

DICLOFENAC ACID/[2-(2,6-DICHLORO-PHENYLAMINO)-PHENY]-ACETIC ACID,Diclofenac 2-ANILINOPHENYLACETIC ACID DICLOFENAC POTASSIUM /POTASSIUM [2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE DICLOFENAC DIETHYLAMINE Diclofenac epolamine 2-(2-Bromo-6-chlorophenyl)amino)-phenylacetic acid sodium salt 95% 1-(2,6-Dichlorophenyl)indole-2,3-dione 2,4'-Dichlorobenzhydrol Diclofenac Acyl--D-glucuronide Allyl Ester 2,6-Dichloro-N-(4-chlorophenyl)-benzeneacetaMide 2-CHLORO-N-(2,6-DICHLOROPHENYL)ACETAMIDE 9H-Carbazole-1-acetic acid, 8-chloro- Diclofenac-13C6-Na hydrate (see Data Sheet) N-(2,6-dichlorophenyl)-N-phenylacetamide 2-(2,6-Dichloroanilino)-Phenylglyoxylic acid Diclofenac Impurity 7 2,6-DICHLORODIPHENYLAMINE 3'-hydroxy-4'-methoxydiclofenac

  • DICLOFENAC-D4
  • DICLOFENAC-D4 (PHENYL-D4)
  • 2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,
  • Diclofenac-D4 (Major)
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid
  • D4-Diclofenac
  • [2H4]-Diclofenac
  • Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci
  • 153466-65-0
  • C14H7D4Cl2NO2
  • C14H7Cl2D4NO2
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals