BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE

Product Name: BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE
CAS No.: 116673-45-1
Chemical Name: BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE
Synonyms: TRANS-BTP DIOXOLANE;BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;(2R,4R)-rel-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane;TRANS-(+/-)-2,4-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;(+/-) TRANS-2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;1,3-Dioxolane, 2,4-bis(3,4,5-trimethoxyphenyl)-, (2R,4R)-rel-
CBNumber: CB1683314
Molecular Formula: C21H26O8
Formula Weight: 406.43
MOL File: 116673-45-1.mol

More

Less

BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Property

Boiling point:: 508.3±50.0 °C(Predicted)
Density: 1.184±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≤35mg/ml in ethanol;50mg/ml in DMSO;50mg/ml in dimethyl formamide
form: White to off-white solid.

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: J67356
Product name: (±)-trans-2,5-Bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane
Packaging: 1mg
Price: $56.4
Updated: 2021/12/16

Alfa Aesar

Product number: J67356
Product name: (±)-trans-2,5-Bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane
Packaging: 5mg
Price: $220
Updated: 2021/12/16

Cayman Chemical

Product number: 60950
Product name: (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 60950
Product name: (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane
Purity: ≥98%
Packaging: 5mg
Price: $182
Updated: 2024/03/01

Cayman Chemical

Product number: 60950
Product name: (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane
Purity: ≥98%
Packaging: 10mg
Price: $322
Updated: 2024/03/01

More

Less

BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Chemical Properties,Usage,Production

Uses

A potent and selective platlet activating factor

Biological Activity

(±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane, also known as trans-btp dioxolane, is a paf receptor antagonist [1].platelet activating factor (paf), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages. paf play important roles in a variety of pathophysiological states including acute allergy, inflammation, asthma, gastrointestinal ulceration, and toxic shock [1].(±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a paf receptor antagonist. in the rabbit washed platelet assay, (±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane showed good competitive paf antagonism with ki value of 0.3 μm, whereas the cis-isomer was much less active.

References

[1]. corey, e.j.,chen, c.p., and parry, m.j. dual binding modes to the receptor for platelet activating factor (paf) of anti-paf trans-2,5-diarylfurans. tetrahedron letters 29, 2899-2902 (1988).

BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Suppliers

Canada 1 China 24 Germany 2 Switzerland 1 United Kingdom 2 United States 5 USA 1 Global 36

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55672
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

116673-45-1, BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANERelated Search:

3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(S] β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate P-ANISALDEHYDE DIMETHYL ACETAL VANILLIN PROPYLENE GLYCOL ACETAL 2-(3,4-Dimethoxyphenyl)ethanol (S)-(+)-2-METHOXY-2-PHENYLETHANOL 3,5-DIMETHOXY-4-HYDROXYPHENYLMETHYL CARBINOL DIVERATRYL ETHER BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE 2-(3,5-DIMETHOXYPHENYL)ETHANOL 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL (1R)-1-(3-METHOXYPHENYL)ETHANOL 1-(3,4-DIMETHOXYPHENYL)ETHANOL 3,4,5-TRIMETHOXYBENZALDEHYDE DIMETHYL ACETAL 3,4,5-TRIMETHOXYPHENYLMETHYL CARBINOL (+/-) CIS-2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE 2,5-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane

BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE

TRANS-BTP DIOXOLANE

(+/-) TRANS-2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE

TRANS-(+/-)-2,4-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE

(2R,4R)-rel-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane

1,3-Dioxolane, 2,4-bis(3,4,5-trimethoxyphenyl)-, (2R,4R)-rel-

116673-45-1

Aromatics Compounds

Aromatics

Heterocycles