Sulforaphene
Pharmacological action Cancer Treatment- Product Name
- Sulforaphene
- CAS No.
- 592-95-0
- Chemical Name
- Sulforaphene
- Synonyms
- sativin;RAPHANIN;Sul aphene;sulforaphene;Sulphoraphen;L-SULFORAPHENE;S-SULFORAPHENE;L-SULPHORAPHENE;SULFORAPHENE, L-;Sulforaphen (6CI)
- CBNumber
- CB1686355
- Molecular Formula
- C6H9NOS2
- Formula Weight
- 175.27
- MOL File
- 592-95-0.mol
Sulforaphene Property
- alpha
- D19 -107° (c = 1.37 in chloroform); D14 -136° (c = 1.38 in alcohol)
- Boiling point:
- bp0.015 125-130°
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under inert atmosphere
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethylacetate (Slightly)
- form
- Slightly yellowish liquid.
- color
- Colourless to Yellow
- CAS DataBase Reference
- 592-95-0
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 17152
- Product name
- L-Sulforaphene
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 17152
- Product name
- L-Sulforaphene
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $166
- Updated
- 2024/03/01
- Product number
- 17152
- Product name
- L-Sulforaphene
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $275
- Updated
- 2024/03/01
- Product number
- S699440
- Product name
- Sulforaphene
- Packaging
- 10mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- CS-0022676
- Product name
- Sulforaphene
- Purity
- 98.01%
- Packaging
- 10mg
- Price
- $202
- Updated
- 2021/12/16
Sulforaphene Chemical Properties,Usage,Production
Pharmacological action
Sulforaphene, or raphanin, is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described by G. Ivanovics and S. Horvath in 1947. Sulforaphene inhibits activity of viruses, some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli. The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione. The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in traditional Chinese medicine. However, in the abstract to his 1947 paper, Ivanovics noted that because sulforaphene is highly toxic, it did not "hold the promise of a useful therapeutic agent".
Cancer Treatment
Sulforaphene may be a potential anti-triple negative breast cancer natural compound and its antiproliferation effects may be mediated by tumor suppressor Egr1; it has chemotherapeutic potential, it promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation; it enhances radiosensitivity of hepatocellular carcinoma through suppression of the NF-κB pathway. Sulforaphene has anti-proliferative and antibacterial properties. Sulforaphene also has herbicidal activity, the ED50 of it against velvetleaf seedlings was approximately 2×10-4 M.
Uses
Sulforaphene is an extract from the seeds of Raphanus sativus and displays anti-inflammatory and anti-cancer activity.
Synthesis Reference(s)
Tetrahedron, 22, p. 2139, 1966 DOI: 10.1016/S0040-4020(01)82133-5
Sulforaphene Preparation Products And Raw materials
Raw materials
Preparation Products
Sulforaphene Suppliers
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View Lastest Price from Sulforaphene manufacturers
- Product
- Sulforaphene 592-95-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- >98%
- Supply Ability
- 1000 kg
- Release date
- 2024-04-25
- Product
- Sulforaphene 592-95-0
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-05-12
- Product
- Sulforaphene 592-95-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-12