Erythromycin ethylsuccinate

Product Name: Erythromycin ethylsuccinate
CAS No.: 1264-62-6
Chemical Name: Erythromycin ethylsuccinate
Synonyms: Esinol;Evesin;Refkas;Anamycin;Arpimycin;E-Mycin e;Eryliquid;Monomycin;Sigapedil;Wyamycin E
CBNumber: CB1701234
Molecular Formula: C43H75NO16
Formula Weight: 862.05
MOL File: 1264-62-6.mol

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Erythromycin ethylsuccinate Property

Melting point:: 219-224 C
Boiling point:: 778.19°C (rough estimate)
Density: 1.1417 (rough estimate)
refractive index: 1.5280 (estimate)
Flash point:: >110°(230°F)
storage temp.: Sealed in dry,Room Temperature
solubility: ethanol: soluble50mg/mL
form: solid
pka: 13.09±0.70(Predicted)
color: white
Water Solubility: Freely soluble in organic solvents, practically insoluble in water
Stability:: Hygroscopic
InChIKey: NSYZCCDSJNWWJL-UHFFFAOYSA-N
SMILES: C1(OC(=O)CCC(OCC)=O)C(N(C)C)CC(C)OC1OC1C(CC(C(C(C(O)C(O)(C)C(CC)OC(=O)C(C)C(OC2OC(C)C(O)C(C)(OC)C2)C1C)C)=O)C)(O)C
CAS DataBase Reference: 1264-62-6

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 42/43-36/37/38
Safety Statements: 36-26
WGK Germany: 2
RTECS: WM9800000
HS Code: 29419000
Hazardous Substances Data: 1264-62-6(Hazardous Substances Data)
Toxicity: LD50 oral in mouse: > 10gm/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001845
Product name: Erythromycin ethylsuccinate for impurity P identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 15 mg
Price: $235
Updated: 2025/07/31

Sigma-Aldrich

Product number: E1500000
Product name: Erythromycin ethyl succinate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1245008
Product name: Erythromycin ethyl succinate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $374
Updated: 2025/07/31

Sigma-Aldrich

Product number: E8755
Product name: Erythromycin ethyl succinate
Packaging: 5g
Price: $84.5
Updated: 2023/06/20

Sigma-Aldrich

Product number: PHR1610
Product name: Erythromycin ethyl succinate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 250mg
Price: $113
Updated: 2025/07/31

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Erythromycin ethylsuccinate Chemical Properties,Usage,Production

Chemical Properties

Erythromycin ethylsuccinate is a white powder or crystals, odourless and tasteless. It is insoluble in water, slightly soluble in diethyl ether, and readily soluble in anhydrous ethanol, acetone or chloroform.

Uses

A broad spectrum antibiotic commonly targeting bacteria responsible for respiratory tract infections

Definition

ChEBI: Erythromycin ethylsuccinate is a erythromycin derivative that is erythromycin A in which the hydroxy group at position 3R is substituted by a (4-ethoxy-4-oxobutanoyl)oxy group. It is used for the treatment of a wide variety of bacterial infections. It is a succinate ester, a cyclic ketone, an erythromycin derivative and an ethyl ester. It is functionally related to an erythromycin A.

Application

Erythromycin Ethylsuccinate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations[1][2][3] by various chromatography techniques.

brand name

E-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).

General Description

Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2＇-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.

References

[1] FAHIMEH KAMAREI . Development of a stability-indicating high performance liquid chromatography method for assay of erythromycin ethylsuccinate in powder for oral suspension dosage form[J]. Arabian Journal of Chemistry, 2014, 7 6: Pages 1079-1085. DOI:10.1016/j.arabjc.2011.01.004.
[2] B. LIAWRUANGRATH S. L. High performance thin layer chromatographic determination of erythromycin in pharmaceutical preparations[J]. Chromatographia, 2001, 54 5-6: 405-408. DOI:10.1007/BF02492693.
[3] JACQUELINE WARDROP . Determination of Erythromycin and Related Substances in Enteric‐Coated Tablet Formulations by Reversed‐Phase Liquid Chromatography[J]. Journal of pharmaceutical sciences, 2000, 89 9: Pages 1097-1105. DOI:10.1002/1520-6017(200009)89:9<1097::AID-JPS1>3.0.CO;2-D.

Erythromycin ethylsuccinate Preparation Products And Raw materials

Raw materials

Succinic anhydride Tetrahydrofuran Erythromycin

Preparation Products

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Erythromycin ethylsuccinate Suppliers

Bangladesh 2 Belgium 2 Brazil 1 Canada 1 China 288 Europe 3 France 3 Germany 7 India 57 Indonesia 1 Italy 1 Japan 1 Malaysia 2 Singapore 2 South Korea 2 Spain 2 Switzerland 1 The Netherlands 1 United Kingdom 8 United States 37 Venezuela 1 Global 423

Xi’an Lijun Pharmaceutical Co., Ltd

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J & K SCIENTIFIC LTD.

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Sinopharm Chemical Reagent Co,Ltd.

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Spectrum Chemical Manufacturing Corp.

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View Lastest Price from Erythromycin ethylsuccinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Erythromycin ethylsuccinate 1264-62-6
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: USP40
Supply Ability: 8000kg/month
Release date: 2021-06-10

Hebei Chuanghai Biotechnology Co., Ltd

Product: Erythromycin ethylsuccinate 1264-62-6
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Erythromycin Ethylsuccinate 1264-62-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-04-02

1264-62-6, Erythromycin ethylsuccinate Related Search:

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erythrocinethylsuccinate

erythromycin,mono(ethylsuccinate)

erythromycin,mono(ethylsuccinate)(ester)

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Erythromycin Ethylsuccinate (200 mg)

Erythromycin ethyl s

Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate

Wyamycin E

ErythroMycin Ethylsuccinate API

butanedioic acid O4-[(2S,3R,5R)-5-(dimethylamino)-2-[[(3R,4R,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[[(2R,3R,4S,5R)-5-hydroxy-4-methoxy-3,4-dimethyl-2-oxanyl]oxy]-3,5,7,9,11,13-hex

Erythromycin Impurity 17(Erythromycin Ethylsuccinate)

Erythromycin Ethylsuccinate-D5

ERYTHROMYCINETHYLSUCCINATE,USP

Anamycin

Arpimycin

Durapaediat

E-Mycin e

Eryliquid

Erythro ES

Erythro-Holz

Erythromycin ethyl succinate (6CI)

Erythromycin, 2'-(ethyl succinate) (7CI)

Erythromycin, mono(ethyl succinate) (ester) (8CI)

Esinol

Evesin

Monomycin

Oxacyclotetradecane, erythromycin deriv.

Paediathrocin

Refkas

Sigapedil

Succinic acid, ethyl ester, monoester with erythromycin (8CI)

ErythroMycin ethyl succina

erythroped

succinicacid,monoethylester,monoesterwitherythromycin

ERYTHROMYCIN ETHLY SUCCINATE.

ERYTHROMYCIN ETHYLSUCCINATE EPE(CRM STANDARD)

ERYTHROMYCIN ETHYLSUCCINATE USP(CRM STANDARD)

ERYTHROMYCIN ETHYISUCCINATE USP

Erythromycin Ethylsucinate

Erythromycin ethylsuccinate USP/EP/BP

Erythromycin Ethyl Succinate D6Q: What is Erythromycin Ethyl Succinate D6 Q: What is the CAS Number of Erythromycin Ethyl Succinate D6 Q: What is the storage condition of Erythromycin Ethyl Succinate D6 Q: What are the applications of Erythromycin Ethyl Succinate D6

TIANFU-CHEM 1264-62-6 Erythromycin ethylsuccinate

Erythromycin Ethylsuccinate (1245008)

Erythromycin Ethyisuccinate

Erythromycin ethylsuccinate, 10 mM in DMSO

(2S,3R,4S,6R)-4-(Dimethylamino)-2-(((3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl)oxy)-6-methyltetrahydro-2H-pyran-3-yl ethyl succinate

Erythromycin ethylsuccinate 98%

Erythromycin ethylsuccinate RS

ErythromycinEthylsuccite

D3-Erythromycin Ethylsuccinate

1264-62-6

C43H75NO16

C43H76NO17

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