ChemicalBook > CAS DataBase List > METHYL 2,5-DIHYDROXYCINNAMATE

METHYL 2,5-DIHYDROXYCINNAMATE

Product Name
METHYL 2,5-DIHYDROXYCINNAMATE
CAS No.
63177-57-1
Chemical Name
METHYL 2,5-DIHYDROXYCINNAMATE
Synonyms
ERBSTATIN ANALOG;ERBSTATIN ANALOGUE;3-(2,5-Dihydroxyphenyl)-;2,5-DIHYDROXYMETHYLCINNAMATE;Methyl 2,5-dihyroxycinnamate;METHYL 2,5-DIHYDROXYCINNAMATE;PMethyl 2,5-DihydroxycinnaMate;Methyl 3-(2,5-dihydroxyphenyl)acrylate;2,5-DIHYDROXYCINNAMIC ACID METHYL ESTER;METHYL 2,5-DIHYDROXYCINNAMATE USP/EP/BP
CBNumber
CB1704149
Molecular Formula
C10H10O4
Formula Weight
194.18
MOL File
63177-57-1.mol
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METHYL 2,5-DIHYDROXYCINNAMATE Property

Melting point:
178-180°C
Density 
1.318±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
0.1 M NaOH: soluble
form 
crystalline
color 
yellow
Water Solubility 
Soluble in methanol or 0.1M NaOH. Insoluble in water
CAS DataBase Reference
63177-57-1(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38
Safety Statements 
22-26-36-45
WGK Germany 
3
HS Code 
2918.29.7500
HazardClass 
6.1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2520
Product name
Methyl 2,5-Dihydroxycinnamate
Purity
>96.0%(HPLC)
Packaging
10mg
Price
$86
Updated
2024/03/01
TCI Chemical
Product number
M2520
Product name
Methyl 2,5-Dihydroxycinnamate
Purity
>96.0%(HPLC)
Packaging
100mg
Price
$498
Updated
2024/03/01
Alfa Aesar
Product number
J61612
Product name
Erbstatin analog
Packaging
5mg
Price
$84.5
Updated
2023/06/20
Alfa Aesar
Product number
J61612
Product name
Erbstatin analog
Packaging
1mg
Price
$19.3
Updated
2021/12/16
Cayman Chemical
Product number
10010238
Product name
Erbstatin analog
Purity
≥98%
Packaging
1mg
Price
$14
Updated
2024/03/01
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METHYL 2,5-DIHYDROXYCINNAMATE Chemical Properties,Usage,Production

Chemical Properties

Yellow-Brown Crystalline Powder

Uses

An inhibitor of the EGF receptor associated tyrosine kinase

Uses

A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis

Definition

ChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester.

METHYL 2,5-DIHYDROXYCINNAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from METHYL 2,5-DIHYDROXYCINNAMATE manufacturers

Career Henan Chemical Co
Product
METHYL 2,5-DIHYDROXYCINNAMATE 63177-57-1
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

63177-57-1, METHYL 2,5-DIHYDROXYCINNAMATERelated Search:

H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH AG 825 TYRPHOSTIN A25 Canertinib METHYL 2,5-DIHYDROXYCINNAMATE METHYL 3,4-DIHYDROXYCINNAMATE Methyl cinnamate 6-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER 6-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER 2,5-DIHYDROXYCINNAMIC ACID AURORA 6680 PHENETHYL 6-METHOXY-2H-CHROMENE-3-CARBOXYLATE AURORA 5701 4-METHOXYBENZYL 6-METHOXY-2H-CHROMENE-3-CARBOXYLATE 3-PYRIDINYLMETHYL 6-METHOXY-2H-CHROMENE-3-CARBOXYLATE AURORA 6678 AURORA 6677 AURORA 6682

  • 2,5-DIHYDROXYMETHYLCINNAMATE
  • 2,5-DIHYDROXYCINNAMIC ACID METHYL ESTER
  • ERBSTATIN ANALOG
  • ERBSTATIN ANALOGUE
  • 3-(2,5-Dihydroxy-phenyl)-acrylicacidmethylester
  • METHYL 2,5-DIHYDROXYCINNAMATE
  • Erbstatin analog, Methyl 2,5-dihydroxycinnamate
  • Methyl 2,5-dihyroxycinnamate
  • 2,5-Dihydroxycinnamic acid methyl ester,Erbstatin analog, Methyl 2,5-dihydroxycinnamate
  • 3-(2,5-Dihydroxyphenyl)-
  • 2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, Methyl ester
  • 3-(2,5-Dihydroxyphenyl)-2-propenoic acid methyl ester
  • Methyl 3-(2,5-dihydroxyphenyl)acrylate
  • PMethyl 2,5-DihydroxycinnaMate
  • (E)-3-(2,5-dihydroxyphenyl)-2-propenoic acid methyl ester
  • METHYL 2,5-DIHYDROXYCINNAMATE USP/EP/BP
  • Methyl 2,5 dihydroxycinnamate,Inhibitor,Methyl 2,5-dihydroxycinnamate,Epidermal growth factor receptor,EGFR,Methyl 2,5dihydroxycinnamate,inhibit,HER1,ErbB-1
  • 63177-57-1
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Kinase/Phosphatase Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Epidermal Growth Factor Receptor (EGFR)
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • All Inhibitors
  • Inhibitors
  • Tyrosine Kinase Inhibitors