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GALAXOLIDE

Product Name
GALAXOLIDE
CAS No.
1222-05-5
Chemical Name
GALAXOLIDE
Synonyms
HHCB;ABBALIDE;HEXAMETHYLINDANOPYRAN;Galoxolide;GALAXOLIDE PURE;1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYLCYCLOPENTA[G]-2-BENZOPYRAN;Musk50;Pearlide;GALAXOLIDE;Jiale musk
CBNumber
CB1706143
Molecular Formula
C18H26O
Formula Weight
258.4
MOL File
1222-05-5.mol
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GALAXOLIDE Property

Melting point:
57-58°
Boiling point:
304 °C(lit.)
Density 
1.044 g/mL at 25 °C(lit.)
vapor pressure 
0.073Pa at 25℃
refractive index 
n20/D 1.5215(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow
Odor
at 100.00 %. strong diffusive sweet floral musk
Odor Type
musk
Water Solubility 
1.65mg/L at 25℃
LogP
5.3 at 25℃
CAS DataBase Reference
1222-05-5(CAS DataBase Reference)
EPA Substance Registry System
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (1222-05-5)
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Safety

Hazard Codes 
Xi,N
Risk Statements 
38-50/53
Safety Statements 
26-36-61
RIDADR 
UN 3082 9 / PGIII
WGK Germany 
3
HS Code 
2932.99.7000
HazardClass 
9
PackingGroup 
III
Hazardous Substances Data
1222-05-5(Hazardous Substances Data)
Toxicity
LD50 skin in rat: > 5gm/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H320Causes eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W520608
Product name
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran solution
Purity
50% in diethyl phthalate
Packaging
sample
Price
$54.6
Updated
2023/01/07
Sigma-Aldrich
Product number
W520608
Product name
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran solution
Purity
50% in diethyl phthalate
Packaging
1kg
Price
$83.8
Updated
2022/05/15
TCI Chemical
Product number
G0415
Product name
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
G0415
Product name
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)
Packaging
250g
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
57524
Product name
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
Purity
analytical standard
Packaging
10mg
Price
$125
Updated
2024/03/01
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GALAXOLIDE Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless to Pale Yellow Oil

Chemical Properties

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]benzopyran is a viscous liquid with a musk-like odor. It is one of the most frequently used synthetic, artificial musk fragrances.The starting material for its synthesis is 1,1,2,3,3-pentamethylindane, which is prepared by cycloaddition of tert-amylene to α-methylstyrene. The pentamethylindane is hydroxyalkylated with propylene oxide in a Friedel–Crafts reaction using aluminum chloride as a catalyst (analogous to the synthesis of phenylethyl alcohol from benzene and ethylene oxide . Ring closure of the resulting 1,1,2,3,3-pentamethyl-5-(β-hydroxyisopropyl)indane is accomplished with paraformaldehyde and a lower aliphatic alcohol via the acetal or with paraformaldehyde and a carboxylic acid anhydride via the acylate.
The commercial product is diluted with solvents (e.g., diethyl phthalate, isopropyl myristate, benzyl benzoate) to make it less viscous. It is alkali-stable and does not discolor in light. Therefore, it is a popular ingredient of perfume compositions for soaps, detergents, and cosmetics and is used in large amounts.

Uses

Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.

Definition

ChEBI: An organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics.

General Description

1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran is an isochromone with a strong musk odor, commonly used in fragrances.

Flammability and Explosibility

Not classified

Trade name

Galaxolide® (IFF), Astromusk (Agan),Musk YingHai (YingHai).

GALAXOLIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GALAXOLIDE Suppliers

Americas 1 Australia 1 Canada 2 China 188 Europe 1 France 3 Germany 8 India 32 Italy 1 Japan 2 Mexico 1 Singapore 1 Spain 3 Switzerland 2 United Kingdom 8 United States 48 Global 302
Aladdin Scientific
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Waterstone Technology, LLC
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Parchem Fine & Specialty Chemicals
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Alichem Inc.
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Glentham Life Sciences Ltd
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International Flavors & Fragrances Inc. (IFF)
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Nice Group Inc
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Amy@nicegroupinc.com
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Phoenix Aromas & Essential Oils, LLC
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MilliporeSigma (Sigma-Aldrich Corp.)
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TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
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Taytonn ASCC Pte Ltd
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Lluch Essence S.L.
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AK Scientific, Inc.
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Vigon International, Inc.
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Spectrum Chemical Mfg. Corp.
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United States Biological
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Prodasynth
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Beijing Lys Chemicals Co, LTD.
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Penta International Corporation
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Azelis UK Ltd.
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Pell Wall Perfumes
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OQEMA
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Augustus Oils Ltd
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Jiangyin Healthway International Trade Co., Ltd
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ECSA Chemicals
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Vigon International
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Zanos Ltd.
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PerfumersWorld Ltd.
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Indukern, S.A. F&F Ingredients Division
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Global Essence Inc.
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Anhui Primechem
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The John D. Walsh Company, Inc
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The Good Scents Company
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M&U International LLC
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Penta Manufacturing Company
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Perfumers World
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View Lastest Price from GALAXOLIDE manufacturers

Hebei Longbang Technology Co., Ltd
Product
GALAXOLIDE 1222-05-5
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-27
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
GALAXOLIDE 1222-05-5
Price
US $60.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-30
HebeiShuoshengImportandExportco.,Ltd
Product
GALAXOLIDE 1222-05-5
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05

1222-05-5, GALAXOLIDERelated Search:

2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Methyl tetrahydrophthalic anhydride Musk ketone Isochroman 1,1,3,3,5-PENTAMETHYL-4,6-DINITROINDANE GALAXOLIDE 2-(4-tert-Butylphenyl)ethanol 4-N-BUTYLPHENETHYL ALCOHOL 2-(3,4-DIMETHYLPHENYL)ETHANOL 2,4-Dimethylphenethylalcohol97% 1-(4-Isobutylphenyl)ethanol 1,1,3,3,5-pentamethylindan 2,5-DIMETHYLPHENETHYL ALCOHOL 1-(2,4-DIMETHYLPHENYL)ETHANOL 4-(TERT-BUTYL)-ALPHA-METHYLBENZYL ALCOHOL p-isopropylphenethyl alcohol 5-HYDROXYMETHYLINDANE 1,1,4,6-Tetramethylindane

  • ABBALIDE
  • 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYLCYCLOPENTA[G]-2-BENZOPYRAN
  • 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYL-CYCLOPENTA-GAMMA-2-BENZOPYRAN
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta(g)-2-benzopyra
  • GALAXOLIDE
  • GALAXOLIDE 50
  • GALAXOLIDE 50 BB
  • GALAXOLIDE 50 IPM
  • HHCB
  • Pearlide
  • 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-.alpha.-2-benzopyran
  • 4,6,6,7,8,8-hexamethyl-1,3,4,7-tetrahydrocyclopenta[g]isochromene
  • HHCB (Galaxolide)
  • Hexahydro-4,6,6,7,8,8-hexamethyl cyclopenta-γ-2-benzopyran
  • Cyclopentag-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran solution
  • HEXAHYDROHEXAMETHYLCYCLOPENTA(G)-2-BENZOPYRAN
  • 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYLINDINO[5,6-C]PYRAN
  • GALAXOLIDE(HHCB)
  • HEXAHYDRO-4,6,6,7,8-HEXAMETHYLCYCLOPOPENTA-GAMMA-2-BENZOPYRAN
  • PEARLIDE PURE
  • Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,7,8,8-hexamethyl-
  • GALAXOLIDE 50% IN B.B.
  • GALAXOLIDE 50% IN D.E.P.
  • GALAXOLIDE 50% IN I.P.M.
  • GALAXOLIDE 70% IN D.E.P.
  • GALAXOLIDE PURE
  • 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexaMethylcyclopenta[g]-2-benzopyrane
  • Galaxolide (solution 50% in diethyl phthalate)
  • 1,3,4,6,7,8-Hexahydro-4,6,6,8,8,8-hexamethylcyclopenta-2-benzopyran
  • HEXAMETHYLINDANOPYRAN
  • Galaxolide Dpg
  • hexamethylindeno(5,6-c)pyran
  • GALAXOLIDE / 4,6,6,7,8,8-Hexamethyl- 1,3,4,6,7,8- hexahydrocyclopenta[g]isochro
  • 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexaMethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)
  • Galaxolide (Mixture of Diastereomers)
  • HHCB (Galaxoli
  • 8-Hexahydro-4
  • 8-hexamethylcyclopenta[g]-2-benzopyran
  • Galaxolide Abbalide
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta[g]-2-benzopyra
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno(5,6
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno(5,6-c)pyran
  • 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,
  • 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
  • Galoxolide
  • Musk50
  • Hexahydromethyl cyclopentabenzopyran (~50%diethyl phthalate)
  • GALAXOLIDE USP/EP/BP
  • Musk Yinghai Pure
  • Galaxolide standard solution
  • musk gx 100%
  • musk gx 50% in DEP
  • musk gx 50% in DPG
  • musk gx 50% in BB
  • musk gx 50% in IPM
  • Factory Supply Galaxolide Price?1222-05-5?in Stock
  • High Purity CAS?1222-05-5?Galaxolide 50% Pure DEP