Musk ketone

Product Name: Musk ketone
CAS No.: 81-14-1
Chemical Name: Musk ketone
Synonyms: KETONE MOSCHUS;(-)-Licarin A;2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene;1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon;MOSCHUS;Ketone musk;MUSK KETONE;Musk ketone 0;MOSCHUS KETON;MUSK KETONE 98+%
CBNumber: CB5458527
Molecular Formula: C14H18N2O5
Formula Weight: 294.3
MOL File: 81-14-1.mol

More

Less

Musk ketone Property

Melting point:: 134-137 °C
Boiling point:: 436.08°C (rough estimate)
Density: 1.2051 (rough estimate)
vapor pressure: 0.001Pa at 25℃
refractive index: 1.5110 (estimate)
Flash point:: 2 °C
storage temp.: 2-8°C
solubility: DMSO : 250 mg/mL (849.47 mM; Need ultrasonic)
Odor: at 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery
Odor Type: musk
Water Solubility: Insoluble (<0.1 g/100 mL at 20 ºC)
BRN: 2062638
Stability:: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
InChIKey: WXCMHFPAUCOJIG-UHFFFAOYSA-N
LogP: 4.24 at 25℃
CAS DataBase Reference: 81-14-1(CAS DataBase Reference)
NIST Chemistry Reference: 2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone(81-14-1)
EPA Substance Registry System: Musk ketone (81-14-1)

More

Less

Safety

Hazard Codes: F,Xn,N
Risk Statements: 11-20/21/22-36-50/53-40
Safety Statements: 16-36/37-61-60-46
RIDADR: UN1648 3/PG 2
WGK Germany: 2
RTECS: KM5775841
HS Code: 2914790060
Hazardous Substances Data: 81-14-1(Hazardous Substances Data)
Toxicity: Both the acute oral LD₅₀ in rats and the acute dermal LD₅₀ in rabbits exceeded 10 g/kg (Fogleman, 1970).

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

H351Suspected of causing cancer

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 46377
Product name: Musk ketone solution
Purity: 100 μg/mL in acetonitrile, analytical standard
Packaging: 2ml
Price: $75
Updated: 2022/05/15

Sigma-Aldrich

Product number: S342963
Product name: 4'-TERT-BUTYL-2',6'-DIMETHYL-3',5'-DINITROACETOPHENONE
Purity: AldrichCPR
Packaging: 1g
Price: $179
Updated: 2024/03/01

Sigma-Aldrich

Product number: W522902
Product name: Musk ketone
Purity: ≥98%
Packaging: sample
Price: $52
Updated: 2022/05/15

AK Scientific

Product number: 6206AF
Product name: Musk ketone
Packaging: 5g
Price: $14
Updated: 2021/12/16

AK Scientific

Product number: 6206AF
Product name: Musk ketone
Packaging: 100g
Price: $68
Updated: 2021/12/16

More

Less

Musk ketone Chemical Properties,Usage,Production

Chemical Properties

White to light yellow crystal powde

Chemical Properties

It forms yellowish crystals with a sweet, very persistent, slightly animal musk odor.Musk ketone is prepared by Friedel–Crafts acetylation of 1,3-dimethyl-5-tert-butylbenzene and nitration of the resulting 2,6- dimethyl-4-tert-butylacetophenone with nitric acid.
Musk ketone is widely used as a fixative in blossom and fantasy compositions.

Occurrence

Has apparently not been reported to occur in nature.

Uses

Musk ketone is used as fragrance and fixative in after-shave lotions, perfumes, ete.

Definition

ChEBI: 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone is an aromatic ketone.

Preparation

Nitration of the corresponding benzene derivative (Bedoukian, 1967).

General Description

Light yellow crystalline solid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

Flash point data is not available for Musk ketone, however, Musk ketone is probably combustible.

Flammability and Explosibility

Not classified

Purification Methods

Purify the ketone by recrystallisation from MeOH. It has a strong odour of musk and is used in perfumery. [Fuson et al. J Org Chem 12 587 1947, Beilstein 7 IV 808.]

Musk ketone Preparation Products And Raw materials

Raw materials

1-tert-Butyl-3,5-dimethylbenzene 2-Methyl-1-propanol 4'-tert-Butylacetophenone m-Xylene Zinc chloride Ferric chloride

Preparation Products

More

Less

Musk ketone Suppliers

China 226 Europe 4 France 1 Germany 3 India 5 South Korea 1 Switzerland 1 United Kingdom 10 United States 47 USA 1 Global 299

Beijing Earlybird Industry Development Co.,Ltd.

Tel: +86-010-62256312-65 +86-13552740132
Email: info@earlybd.com
Country: China
ProdList: 136
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

jiliang chemicals

Tel: 21-62165282 15801962796;
Fax: 021 61153784
Email: bidingchem@163.com
Country: China
ProdList: 1165
Advantage: 60

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9664
Advantage: 60

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4941
Advantage: 60

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9901
Advantage: 58

More

Less

View Lastest Price from Musk ketone manufacturers

Hebei Duling International Trade Co. LTD

Product: Dexpanthenol 81-14-1
Price: US $50.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20 tons
Release date: 2023-03-15

Hebei Kingfiner Technology Development Co. , Ltd.

Product: Musk ketone 81-14-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000kg
Release date: 2023-11-01

Hebei Mojin Biotechnology Co., Ltd

Product: Musk ketone 81-14-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-30

81-14-1, Musk ketoneRelated Search:

N,N-Dimethyldodecylamine tert-Butyl methyl ether Muscone ETHANE Dimethyl ether Musk xylene 3-Nitroacetophenone Dimethyl fumarate L-PICEIN Buprofezin 4-Nitroacetophenone Dimethyl phthalate N,N-Dimethylformamide tert-Butyl hydroperoxide tert-Butyldimethylsilyl chloride Dimethyl sulfoxide Dimethyl sulfide Acetophenone

2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene

3',5'-Dinitro-4'-tert-butyl-2',6'-dimethylacetophenone

3, 5-Dinitro-4-t-butyl-2, 6-dimethylacetophenone

Ketone Moschus,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Musk ketone

Musk ketone,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus

Musk ketone 0

Ketone Moschus >=97.0% (N)

1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon

1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-ethanon

1-Acetyl-4-tert-butyl-2,6-dimethyl-3,5-dinitrobenzene

2-acetyl-5-tert-butyl-4,6-dinitroxylene

3,5-Dinitro-2,6-dimethyl-4-tert-butyl acetophenone

MUSK KETONE 98+%

4-Aceto-3,5-dimethyl-2,6-dinitro-tert-butylbenzene

2,6-DIMETHYL-3,5-DINITRO-4-TERT-BUTYLACETOPHENONE(MUSKKETONE)

3’,5’-dinitro-2’,6’-dimethyl-4’-tert-butylacetophenone

MOSCHUS KETON

1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone

2',6'-Dimethyl-3',5'-dinitro-4'-tert-butylacetophenone

3-METHYLCYCLOPENTADECANONE (D,L-MUSCONE)

4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus

Methylcyclopentadecanone

4’-tert-butyl-2’,6’-dimethyl-3’,5’-dinitro-acetophenon

4’-tert-Butyl-2’,6-dimethyl-3’,5’dmnitroacetophenone

4-t-Butyl-2,6-dimethyl-3,5-dinitroacetophenone

4-tert-Butyl-2,6-dimethyl-3,5-dinitroactophenone

Acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro-

Acetyl-dinitro-butyl-xylene

Dinitro-tert-butylxylyl methyl ketone

Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-

Ethanone,1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-

Ketone musk

MUSK KETONE

MOSCHUS

2,6-DINITRO-3,5-DIMETHYL-4-ACETYL-TERT-BUTYLBENZENE

1-[4-(TERT-BUTYL)-2,6-DIMETHYL-3,5-DINITROPHENYL]ETHAN-1-ONE

1-(4-TERT-BUTYL-2,6-DIMETHYL-3,5-DINITRO-PHENYL)-ETHANONE

4-TERT-BUTYL-3,5-DINITRO-2,6-DIMETHYL ACETOPHENONE

4-TERT-BUTYL-2,6-DIMETHYL-3,5-DINITROACETOPHENONE

KETONE MOSCHUS

Synthetic Musk ketone

Musk ketone Solution in Methanol, 100μg/mL

Musk ketone USP/EP/BP

Best Price CAS 81-14-1 Musk Ketone Powder

(-)-Licarin A

81-14-1

81-41-1

CH3COC6HC4H9CH3NO22

CH3C15H27O

CH33CC6NO22CH32COCH3

C13 to C14

Carbonyl Compounds

Building Blocks

Ketones

Organic Building Blocks

PP

KetonesAlphabetic

Analytical Standards