2-BROMO-6-METHYL-4-NITROANILINE

Product Name: 2-BROMO-6-METHYL-4-NITROANILINE
CAS No.: 102170-56-9
Chemical Name: 2-BROMO-6-METHYL-4-NITROANILINE
Synonyms: 6-Bromo-2-methyl-4-nitroaniline;2-Methyl-4-nitro-6-bromoaniline;2-BROMO-6-METHYL-4-NITROANILINE;2-Bromo-6-methyl-4-nitroaniline,98%;2-BROMO-6-METHYL-4-NITROANILINE 98%;2-Bromo-6-methyl-4-nitrobenzenamine;2-BroMo-6-Methyl-4-nitro-phenylaMine;Benzenamine, 2-bromo-6-methyl-4-nitro-;2-BROMO-6-METHYL-4-NITROANILINE ISO 9001：2015 REACH
CBNumber: CB1709674
Molecular Formula: C7H7BrN2O2
Formula Weight: 231.05
MOL File: 102170-56-9.mol

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2-BROMO-6-METHYL-4-NITROANILINE Property

Melting point:: 180-184 °C
Boiling point:: 366.0±37.0 °C(Predicted)
Density: 1.7207 (rough estimate)
refractive index: 1.5150 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: -1.34±0.20(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C7H7BrN2O2/c1-4-2-5(10(11)12)3-6(8)7(4)9/h2-3H,9H2,1H3
InChIKey: DCNWQCOXGLGSRC-UHFFFAOYSA-N
SMILES: C1(N)=C(C)C=C([N+]([O-])=O)C=C1Br
CAS DataBase Reference: 102170-56-9

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Safety

Hazard Codes: Xi
Risk Statements: 20/21/22-36/37
Safety Statements: 36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2921430090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 655937
Product name: 2-Bromo-6-methyl-4-nitroaniline
Purity: 97%
Packaging: 5g
Price: $176
Updated: 2023/06/20

TRC

Product number: M425493
Product name: 2-Bromo-6-methyl-4-nitroaniline
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB66370
Product name: 2-Bromo-6-methyl-4-nitroaniline
Packaging: 25g
Price: $64
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB66370
Product name: 2-Bromo-6-methyl-4-nitroaniline
Packaging: 50g
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 045962
Product name: 2-Bromo-6-methyl-4-nitroaniline
Purity: >95%
Packaging: 500mg
Price: $118
Updated: 2021/12/16

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2-BROMO-6-METHYL-4-NITROANILINE Chemical Properties,Usage,Production

Chemical Properties

yellow needles

Synthesis

99-52-5

102170-56-9

General procedure for the synthesis of 2-bromo-6-methyl-4-nitroaniline from 4-nitro-2-methylaniline: 2-methyl-4-nitroaniline (2.0 g, 13.2 mmol) was dissolved in acetonitrile (40 mL) at 60 °C, followed by the addition of N-bromosuccinimide (2.8 g, 15.8 mmol). The reaction mixture was heated to reflux for 3 hours and then cooled to room temperature. The reaction mixture was concentrated and diluted with dichloromethane (50 mL). The organic phase was washed sequentially with 2.5 M sodium hydroxide solution and saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: n-hexane/ethyl acetate, 4/1, v/v) to afford 2-bromo-6-methyl-4-nitroaniline as a yellow solid (2.75 g, 91% yield). Melting point: 178-179°C. Thin layer chromatography Rf value: 0.40 (unfolding agent: n-hexane/ethyl acetate, 5/1, v/v).1H NMR (DMSO-d6, 400MHz) δ 8.15 (d, J=2.5Hz, 1H), 7.93 (d, J=2.1Hz, 1H), 6.53 (s, 2H), 2.23 (s, 3H). Mass spectrum (ESI) m/z: 228.5 [M-H]-.

References

[1] Patent: WO2016/176460, 2016, A1. Location in patent: Page/Page column 97
[2] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 2, p. 597 - 599
[3] European Journal of Medicinal Chemistry, 2017, vol. 131, p. 1 - 13
[4] Journal of the Chemical Society, 1929, p. 1255
[5] Bulletin de la Societe Chimique de France, 1924, vol. <4>35, p. 1328

2-BROMO-6-METHYL-4-NITROANILINE Preparation Products And Raw materials

Raw materials

Zinc oxide Formic acid Diethyl ether Ethyl acetate Lithium Aluminum Hydride 2-Methyl-4-nitroaniline Bromine Dichloromethane Acetic acid 4-Fluoroaniline

Preparation Products

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2-BROMO-6-METHYL-4-NITROANILINE Suppliers

Belgium 1 China 64 Germany 3 India 4 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 11 Global 93

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View Lastest Price from 2-BROMO-6-METHYL-4-NITROANILINE manufacturers

Career Henan Chemical Co

Product: 2-bromo-6-methyl-4-nitroaniline 102170-56-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: G/KG/TON
Release date: 2020-01-28

102170-56-9, 2-BROMO-6-METHYL-4-NITROANILINERelated Search:

4-BROMO-2-METHYL-6-NITROANILINE 4-bromo-N-methyl-2-nitroaniline 2-BROMO-4-METHYL-6-NITROANILINE 2-BROMO-6-METHYL-4-NITROANILINE Disperse Blue 183 2-Amino-3-bromo-5-nitrobenzonitrile 4-Nitroaniline 1-ACETYL-7-BROMO-5-NITROINDOLINE 2-bromo-N-methyl-4-nitroaniline 2-BROMO-3,6-DIMETHYL-4-NITROANILINE 3-bromo-4-methyl-5-nitroaniline 2-bromo-4-methyl-5-nitroaniline 2-amino-3-bromo-5-nitrobenzimidamide N-(2-BROMO-4-NITRO-6-METHYLPHENYL)ACETAMIDE RARECHEM AL BO 0536 N-(4-amino-3-bromo-5-(N-ethylcarbamimidoyl)phenyl)-N-oxohydroxylammonium 1-(2-BROMO-6-METHYL-4-NITROPHENYL)-1H-PYRROLE N-(4-amino-3-bromo-5-(ethoxy(imino)methyl)phenyl)-N-oxohydroxylammonium

2-BROMO-6-METHYL-4-NITROANILINE

2-Methyl-4-nitro-6-bromoaniline

2-BROMO-6-METHYL-4-NITROANILINE 98%

2-Bromo-6-methyl-4-nitroaniline,98%

2-BroMo-6-Methyl-4-nitro-phenylaMine

Benzenamine, 2-bromo-6-methyl-4-nitro-

6-Bromo-2-methyl-4-nitroaniline

2-BROMO-6-METHYL-4-NITROANILINE ISO 9001：2015 REACH

2-Bromo-6-methyl-4-nitrobenzenamine

102170-56-9

102172-56-9

H3CC6H2NO2BrNH2

C7H7BrN2O2

Organic Building Blocks

Nitrogen Compounds

Amines

Building Blocks

C7

Anilines, Aromatic Amines and Nitro Compounds

Amines

C7

Nitrogen Compounds