CASPASE-3
- Product Name
- CASPASE-3
- CAS No.
- 169592-56-7
- Chemical Name
- CASPASE-3
- Synonyms
- YAMA;CPP32;CPP321;CASP-3;APOPAIN;CASPASE-3;YAMA HUMAN;CPP32 HUMAN;PROCASPASE-3;APOPAIN HUMAN
- CBNumber
- CB1710614
- Formula Weight
- 0
- MOL File
- Mol file
CASPASE-3 Property
- Melting point:
- 127 °C
- storage temp.
- −70°C
- solubility
- PBS: soluble
- form
- buffered aqueous glycerol solution
Safety
- WGK Germany
- 1
N-Bromosuccinimide Price
- Product number
- SAB4503294
- Product name
- Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $506
- Updated
- 2024/03/01
- Product number
- SAB4503292
- Product name
- Anti-CSPN3 (Cleaved-Asp175) antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $506
- Updated
- 2024/03/01
- Product number
- SAB1305630
- Product name
- ANTI-CLEAVED-CASP3 (ASP175) antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 400μl
- Price
- $481
- Updated
- 2024/03/01
- Product number
- 235417
- Product name
- Caspase-3, Human, Recombinant, E. coli
- Packaging
- 5000u
- Price
- $552
- Updated
- 2023/01/07
- Product number
- 354512
- Product name
- Casp3
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
CASPASE-3 Chemical Properties,Usage,Production
Uses
Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay.
General Description
Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag.
Biochem/physiol Actions
Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B.
CASPASE-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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