O-DESMETHYLGALANTHAMINE
- Product Name
- O-DESMETHYLGALANTHAMINE
- CAS No.
- 60755-80-8
- Chemical Name
- O-DESMETHYLGALANTHAMINE
- Synonyms
- Sanguinine;O-Demethylgalantamine;Galantamine Impurity 7;Galantamine Impurity 6;Galantamine Impurity 3;O-Demethyl-galanthamine;O-DESMETHYLGALANTHAMINE;6-O-Demethylgalanthamine;Galantamine O-Desmethyl Impurity;10-Methyl-galantham-1-ene-3,6-diol
- CBNumber
- CB1712906
- Molecular Formula
- C16H19NO3
- Formula Weight
- 273.33
- MOL File
- 60755-80-8.mol
O-DESMETHYLGALANTHAMINE Property
- Melting point:
- 227-230°C (dec.)
- Boiling point:
- 451.9±45.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 9.39±0.40(Predicted)
- CAS DataBase Reference
- 60755-80-8
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D292030
- Product name
- O-DesmethylGalanthamine
- Packaging
- 2mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FD21272
- Product name
- O-Desmethyl galanthamine
- Packaging
- 5mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 2925CC
- Product name
- Sanguinine
- Packaging
- 2mg
- Price
- $137
- Updated
- 2021/12/16
- Product number
- FD21272
- Product name
- O-Desmethyl galanthamine
- Packaging
- 10mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- 2925CC
- Product name
- Sanguinine
- Packaging
- 10mg
- Price
- $360
- Updated
- 2021/12/16
O-DESMETHYLGALANTHAMINE Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Powder
Uses
A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor
Uses
A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.
Uses
Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series.
Definition
ChEBI: Sanguinine is a benzazepine.