O-DESMETHYLGALANTHAMINE

Product Name: O-DESMETHYLGALANTHAMINE
CAS No.: 60755-80-8
Chemical Name: O-DESMETHYLGALANTHAMINE
Synonyms: Sanguinine;O-Demethylgalantamine;Galantamine Impurity 7;Galantamine Impurity 6;Galantamine Impurity 3;O-Demethyl-galanthamine;O-DESMETHYLGALANTHAMINE;6-O-Demethylgalanthamine;Galantamine O-Desmethyl Impurity;10-Methyl-galantham-1-ene-3,6-diol
CBNumber: CB1712906
Molecular Formula: C16H19NO3
Formula Weight: 273.33
MOL File: 60755-80-8.mol

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O-DESMETHYLGALANTHAMINE Property

Melting point:: 227-230°C (dec.)
Boiling point:: 451.9±45.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO: soluble
form: A solid
pka: 9.39±0.40(Predicted)
color: White to off-white
CAS DataBase Reference: 60755-80-8

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D292030
Product name: O-DesmethylGalanthamine
Packaging: 2mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21272
Product name: O-Desmethyl galanthamine
Packaging: 5mg
Price: $125
Updated: 2021/12/16

AK Scientific

Product number: 2925CC
Product name: Sanguinine
Packaging: 2mg
Price: $137
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21272
Product name: O-Desmethyl galanthamine
Packaging: 10mg
Price: $230
Updated: 2021/12/16

AK Scientific

Product number: 2925CC
Product name: Sanguinine
Packaging: 10mg
Price: $360
Updated: 2021/12/16

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O-DESMETHYLGALANTHAMINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Powder

Uses

A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor

Uses

A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.

Uses

Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series.

Definition

ChEBI: Sanguinine is a benzazepine.

O-DESMETHYLGALANTHAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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O-DESMETHYLGALANTHAMINE Suppliers

Canada 1 China 55 Germany 1 India 6 United Kingdom 1 United States 8 Global 72

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Refsyn Biosciences Pvt., Ltd.

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Pharmaffiliates Analytics and Synthetics P. Ltd

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60755-80-8, O-DESMETHYLGALANTHAMINERelated Search:

Galanthaminium, 7-methyl-, iodide Epigalanthamine N-Oxide AKOS 224-01 AKOS 229-01 Galantamine Hydrobromide (-)-Galanthaminyl (-)-Camphanate Galanthamine O-Desmethyl Galanthamine b-D-Glucuronide AKOS 228-20 Galanthamine-N-oxide O-DESMETHYLGALANTHAMINE

(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol

(4aS,8aS)-11-Methyl-4aα,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzoazepine-3,6β-diol

(8aS)-5,6,9,10,11,12-Hexahydro-11-methyl-4aαH-benzofuro[3a,3,2-ef][2]benzazepine-3,6β-diol

6-O-Demethylgalanthamine

10-Methyl-galantham-1-ene-3b,6-diol

O-Demethyl-galanthamine

Sanguinine

10-Methyl-galantham-1-ene-3,6-diol

O-DESMETHYLGALANTHAMINE

Galantamine O-Desmethyl Impurity

Galantamine Impurity 7

O-Demethylgalantamine

6H-Benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol, 4a,5,9,10,11,12-hexahydro-11-methyl-, (4aS,6R,8aS)-

O-Desmethyl GalantamineQ: What is O-Desmethyl Galantamine Q: What is the CAS Number of O-Desmethyl Galantamine Q: What is the storage condition of O-Desmethyl Galantamine Q: What are the applications of O-Desmethyl Galantamine

Galantamine Impurity 6

Cholinesterase (ChE),anti-acetylcholinesterase,O Desmethyl Galanthamine,Inhibitor,galanthamine-type,ODesmethyl Galanthamine,O-Desmethyl Galanthamine,alkaloids,inhibit

Galantamine Impurity 3

60755-80-8

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals