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Benzyl isocyanate

Product Name
Benzyl isocyanate
CAS No.
3173-56-6
Chemical Name
Benzyl isocyanate
Synonyms
(Isocyanatomethyl)benzene;1-(isocyanatomethyl)benzene;Benzyl isocyate;BENZYL ISOCYANATE;BenzylIsocyanate>Benzylisocyanate,98%;Benzyl isocyanate 98%;Benzyl isocyanate, 99+%;Isocyanatomethyl-benzene;(isocyanatomethyl)-benzen
CBNumber
CB1714526
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
3173-56-6.mol
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Benzyl isocyanate Property

Melting point:
259-261 °C(Solv: acetic acid (64-19-7))
Boiling point:
101-104 °C/33 mmHg (lit.)
Density 
1.078 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.526(lit.)
Flash point:
113 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
color 
Clear colorless to faintly yellow
Water Solubility 
It hydrolyzes with water.
Sensitive 
Moisture Sensitive
BRN 
636508
CAS DataBase Reference
3173-56-6(CAS DataBase Reference)
NIST Chemistry Reference
Benzyl isocyanate(3173-56-6)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
10-36/37/38-42/43-23/24/25
Safety Statements 
23-26-36/37-36/37/39-16
RIDADR 
UN 3080 6.1/PG 2
WGK Germany 
3
10-21
HazardClass 
6.1
PackingGroup 
II
HS Code 
29291090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
227269
Product name
Benzyl isocyanate
Purity
99%
Packaging
25g
Price
$83.2
Updated
2024/03/01
Sigma-Aldrich
Product number
227269
Product name
Benzyl isocyanate
Purity
99%
Packaging
5g
Price
$96.8
Updated
2024/03/01
TCI Chemical
Product number
I0426
Product name
Benzyl Isocyanate
Purity
>99.0%(GC)
Packaging
5g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
I0426
Product name
Benzyl Isocyanate
Purity
>99.0%(GC)
Packaging
25g
Price
$146
Updated
2024/03/01
Alfa Aesar
Product number
L02633
Product name
Benzyl isocyanate, 98%
Packaging
1g
Price
$27.65
Updated
2024/03/01
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Benzyl isocyanate Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO FAINTLY YELLOW LIQUID

Occurrence

benzyl isocyanate is a natural product found in Simicratea welwitschii with data available.?

Uses

Benzyl isocyanate, is used as a protected ammonia equivalent in the stereo selective ring-opening of chiral 2,3-epoxy alcohols (from Sharpless asymmetric epoxidation). The key step in the sequence involves intramolecular cyclization of the carbamate intermediate. It is also used in a multicomponent, stereospecific synthesis of 1,3-oxazinane-2,4-diones employing an Al-salph complex.

Uses

Benzyl isocyanate was used to investigate the kinetics of isocyanate derivatization reaction in a continuous flow glass microfluidics chip. It was also used in a multicomponent, stereospecific synthesis of 1,3-oxazinane-2,4-diones employing an Al-salph complex (674699).

General Description

Benzyl isocyanate inhibits the formation of benzo[a]pyrene (BP)-DNA adduct and posses chemopreventive properties.

Synthesis

The conversion of benzyl azide to benzyl isocyanate (Scheme 1) was selected as the model reaction and it was performed both under conventional conditions and under MW irradiation. Various solvents were compared at a number of temperatures thanks to the versatility of the SynthWave reactor, which provides multiple-sample racks. Experiments were performed at 90, 70 and 50 °C at 14.5 bar of CO2 pressure.

Scheme 1: Synthesis of benzyl isocyanate.
One-pot sequential synthesis of isocyanates and urea derivatives via a microwave-assisted Staudinger–aza-Wittig reaction

Benzyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl isocyanate Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from Benzyl isocyanate manufacturers

Career Henan Chemical Co
Product
Benzyl isocyanate 3173-56-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-15

3173-56-6, Benzyl isocyanateRelated Search:


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