(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE

Product Name: (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE
CAS No.: 86286-50-2
Chemical Name: (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE
Synonyms: 4,5-diphenyl-2-oxazolidinone;(4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone;2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)-;(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one;(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e.;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98%;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98%;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone
CBNumber: CB1717996
Molecular Formula: C15H13NO2
Formula Weight: 239.27
MOL File: 86286-50-2.mol

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(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Property

Melting point:: 227-230 °C (lit.)
Boiling point:: 466.6±45.0 °C(Predicted)
Density: 1.192±0.06 g/cm3(Predicted)
pka: 11.56±0.60(Predicted)
optical activity: [α]20/D 57±4°, c = 2 in methanol
InChI: 1S/C15H13NO2/c17-15-16-13(11-7-3-1-4-8-11)14(18-15)12-9-5-2-6-10-12/h1-10,13-14H,(H,16,17)/t13-,14+/m1/s1
InChIKey: LTENIVFVXMCOQI-KGLIPLIRSA-N
SMILES: O=C1N[C@@H]([C@@H](O1)c2ccccc2)c3ccccc3

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29029090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 454540
Product name: (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone
Purity: 98%
Packaging: 1g
Price: $230
Updated: 2023/01/07

American Custom Chemicals Corporation

Product number: CHM0004668
Product name: (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE
Purity: 95.00%
Packaging: 1G
Price: $744.02
Updated: 2021/12/16

Chemenu

Product number: CM190719
Product name: (4R,5S)-4,5-diphenyloxazolidin-2-one
Purity: 95%
Packaging: 5g
Price: $408
Updated: 2021/12/16

Crysdot

Product number: CD11042084
Product name: (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one
Purity: 95+%
Packaging: 5g
Price: $432
Updated: 2021/12/16

Ambeed

Product number: A253448
Product name: (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one
Purity: 95+%
Packaging: 5g
Price: $518
Updated: 2021/12/16

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(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Chemical Properties,Usage,Production

Chemical Properties

White powder or crystal

Uses

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta .

Preparation

To a stirred suspension of commercially available (10.0 g, 47 mmol) and triethylamine (14.4 mL, 0.10 mol) in dichloromethane (100 mL), diphosgene (3.0 mL, 25 mmol) was added dropwise at 0 °C and the mixture was stirred for 1 h at the same temperature. After concentration in vacuo, the residue was poured into water to precipitate crystals. The crystals were collected by filtration, successively washed with 10% HCl and H2O, and dried in vacuo at 50–60 °C for 3 h to afford 593a as colorless crystals (10.9 g, 97%).

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Suppliers

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86286-50-2, (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONERelated Search:

Diphenylsilanediol (4S,5R)-(-)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE (1S,2R)-2-Amino-1,2-diphenylethanol (R)-(-)-4-Phenyl-2-oxazolidinone (1S 2R)-EPHEDRINE HEMIHYDRATE 98 (4R,5S)-(+)-4-METHYL-5-PHENYL-2-OXAZOLIDINONE (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE (4R,5S)-(+)-3-BUTOXYCARBONYL-METHYL-4,5-DIPHENYL-2-OXAZOLIDINONE Resedine 4-PHENYLOXAZOLIDIN-2-ONE (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE

(4R,5S)-4,5-Diphenyl-2-oxazolidinone

(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one

(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98%

(4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e.

(4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE

(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98%

4,5-diphenyl-2-oxazolidinone

2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)-

(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone

86286-50-2

Oxazolidinone Derivatives

Asymmetric Synthesis

Chiral Auxiliaries

Benzene derivatives

Asymmetric Synthesis

Chiral Auxiliaries

Oxazolidinone Derivatives