ChemicalBook > CAS DataBase List > ATPA
ATPA
- Product Name
- ATPA
- CAS No.
- 140158-50-5
- Chemical Name
- ATPA
- Synonyms
- ATPA;(R,S)-ATPA;ATP synthase α chain;alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate;(RS)-A-AMINO-3-HYDROXY-5-TERT-BUTYL-4-ISOXAZOLEPROPIONIC ACID;(R,S)-ALPHA-AMINO-3-HYDROXY-5-T-BUTYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALPHA-AMINO-3-HYDROXY-5-TERT-BUTYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOXAZOL-4-YL)PROPANOIC ACID;2-Amino-3-(5-(tert-butyl)-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid;4-Isoxazolepropanoic acid, α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-
- CBNumber
- CB1719521
- Molecular Formula
- C10H16N2O4
- Formula Weight
- 228.25
- MOL File
- 140158-50-5.mol
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ATPA Property
- Density
- 1.263±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- DMSO: 10 mg/mL
- form
- solid
- pka
- 2.15±0.10(Predicted)
- color
- white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Tocris
- Product number
- 1107
- Product name
- ATPA
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $227
- Updated
- 2021/12/16
Tocris
- Product number
- 1107
- Product name
- ATPA
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $936
- Updated
- 2021/12/16
Usbiological
- Product number
- 254690
- Product name
- ATPA
- Packaging
- 10mg
- Price
- $480
- Updated
- 2021/12/16
TRC
- Product number
- A790535
- Product name
- (R,S)-ATPA
- Packaging
- 1mg
- Price
- $130
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0021056
- Product name
- ATPA
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $685
- Updated
- 2021/12/16
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ATPA Chemical Properties,Usage,Production
Uses
(R,S)-ATPA is a selective and potent GluR5 kainate receptor agonist (1,2). It inhibits GluK2 kainate receptor-JNK3 protein pathway by activating GABA type A receptor in rat after cerebral ischemia-reperfusion injury (3). (R,S)-ATPA is a neuroprotective agent.
Definition
ChEBI: 2-amino-3-(5-tert-butyl-3-oxo-4-isoxazolyl)propanoic acid is an alpha-amino acid.
Biological Activity
A selective and potent GluR5 kainate receptor agonist (K i = 4.3 nM), inactive at GluR6 (K i > 1 mM) and only weakly active at AMPA receptors (GluR1-4) and the kainate receptors KA-2 and GluR7 (K i values of 6 - 14 μ M). Also available as part of the Kainate Receptor Tocriset™ .
storage
Desiccate at +4°C
ATPA Preparation Products And Raw materials
Raw materials
Preparation Products
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ATPA Suppliers
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140158-50-5, ATPARelated Search:
ATPA
( Z )-2-(2-AMINOTHIAZOL-4-YL)-2-PENTENOIC ACID (ATPA)
ATPA ((RS)-2-AMINO-3-(3-HYDROXY-5-TERT-B,(R,S)-ATPA,ATPA
(R)-ATPA, >97%
(RS)-AMPA
CHEMBRDG-BB 4009738
(R,S)-2-AMINO-3-[5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL]PROPIONIC ACID
2-ISOXAZOL-4-YL-ETHYLAMINE
ATPA
(R)-ATPA
(S)-ATPA