DCC-3014

Product Name: DCC-3014
CAS No.: 1628606-05-2
Chemical Name: DCC-3014
Synonyms: DCC-3014;Vimseltinib;DCC-3014(Vimseltinib);Vimseltinib (DCC-3014);Vimseltinib, 10 mM in DMSO;2-(Isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)pyrimidin-4(3H)-one;4(3H)-Pyrimidinone, 3-methyl-2-[(1-methylethyl)amino]-5-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-;CSF1R,CD117,CSF-1 receptor,DCC 3014,SCFR,inhibit,c-Fms,DCC3014,c-Kit,CSF-1R,Vimseltinib,colony stimulating factor 1 receptor,Inhibitor
CBNumber: CB17244101
Molecular Formula: C23H25N7O2
Formula Weight: 431.49
MOL File: 1628606-05-2.mol

More

Less

DCC-3014 Property

Boiling point:: 609.2±65.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
solubility: DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/ml
pka: 3.20±0.27(Predicted)
form: Solid
color: Off-white to light yellow
InChI: InChI=1S/C23H25N7O2/c1-14(2)27-23-25-12-18(22(31)30(23)5)19-6-7-21(15(3)28-19)32-17-8-9-24-20(10-17)16-11-26-29(4)13-16/h6-14H,1-5H3,(H,25,27)
InChIKey: TVGAHWWPABTBCX-UHFFFAOYSA-N
SMILES: C1(NC(C)C)=NC=C(C2=NC(C)=C(OC3C=CN=C(C4=CN(C)N=C4)C=3)C=C2)C(=O)N1C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0121044
Product name: DCC-3014
Purity: 99.08%
Packaging: 5mg
Price: $380
Updated: 2021/12/16

ChemScene

Product number: CS-0121044
Product name: DCC-3014
Purity: 99.08%
Packaging: 10mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0121044
Product name: DCC-3014
Purity: 99.08%
Packaging: 25mg
Price: $1250
Updated: 2021/12/16

ChemScene

Product number: CS-0121044
Product name: DCC-3014
Purity: 99.08%
Packaging: 50mg
Price: $2000
Updated: 2021/12/16

ChemScene

Product number: CS-0121044
Product name: DCC-3014
Purity: 99.08%
Packaging: 100mg
Price: $2950
Updated: 2021/12/16

More

Less

DCC-3014 Chemical Properties,Usage,Production

Uses

Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

References

[1] Yumi Ahn, et al. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145025A2.
[2] TIMOTHY M. CALDWELL. Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment of Tenosynovial Giant Cell Tumor (TGCT)[J]. Bioorganic & Medicinal Chemistry Letters, 2022, 74: Article 128928. DOI: 10.1016/j.bmcl.2022.128928

DCC-3014 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DCC-3014 Suppliers

China 48 United States 2 Global 50

Shanghai XingMo Biotechnology Co., Ltd.

Tel: +86 13524779951; 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 310
Advantage: 55

Taizhou Zhongzhi Biotechnology Co., Ltd

Tel: 13012344321
Email: 3995296515@qq.com
Country: China
ProdList: 8448
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15727060112
Email: yutianchun2007@126.com
Country: China
ProdList: 9814
Advantage: 58

ChemOrigin Pharm

Tel: 021-15026428026 15026428026
Email: ChemOrigin@126.com
Country: China
ProdList: 348
Advantage: 58

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Country: China
ProdList: 1077
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7992
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

1628606-05-2, DCC-3014Related Search:

DCC-3014

Vimseltinib

CSF1R,CD117,CSF-1 receptor,DCC 3014,SCFR,inhibit,c-Fms,DCC3014,c-Kit,CSF-1R,Vimseltinib,colony stimulating factor 1 receptor,Inhibitor

4(3H)-Pyrimidinone, 3-methyl-2-[(1-methylethyl)amino]-5-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-

2-(Isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)pyrimidin-4(3H)-one

DCC-3014(Vimseltinib)

Vimseltinib (DCC-3014)

Vimseltinib, 10 mM in DMSO

1628606-05-2