SE 175

Product Name
SE 175
CAS No.
258278-64-7
Chemical Name
SE 175
Synonyms
SE 175;SE 175 >=97%;NO PRODRUG, SE 175;JDIVRBDMTYQVOK-UHFFFAOYSA-N;S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE;2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER;Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester
CBNumber
CB1732391
Molecular Formula
C16H13NO6S
Formula Weight
347.34
MOL File
258278-64-7.mol
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SE 175 Property

Boiling point:
493.8±45.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF:50.0(Max Conc. mg/mL);143.53(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);100.47(Max Conc. mM)
Ethanol:11.0(Max Conc. mg/mL);31.58(Max Conc. mM)
form 
A crystalline solid
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S2189
Product name
SE 175
Purity
≥97%
Packaging
10mg
Price
$187
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
5mg
Price
$59
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
10mg
Price
$108
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
50mg
Price
$448
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
100mg
Price
$783
Updated
2024/03/01
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SE 175 Chemical Properties,Usage,Production

Description

SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 20 μM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.

SE 175 Preparation Products And Raw materials

Raw materials

Preparation Products

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SE 175 Suppliers

China 19 Switzerland 1 United States 5 Global 25
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
Email
sales@tybiochem.com
Country
China
ProdList
5448
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49739
Advantage
58

258278-64-7, SE 175Related Search:

SE 175 2-[(4-METHYLBENZYL)SULFANYL]BENZENECARBOXYLIC ACID

  • 2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER
  • JDIVRBDMTYQVOK-UHFFFAOYSA-N
  • NO PRODRUG, SE 175
  • S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE
  • SE 175
  • Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester
  • SE 175 >=97%
  • 258278-64-7
  • Substrates by Enzyme
  • Nitric Oxide Synthase/NO Donor
  • BioChemical
  • Biochemicals and Reagents
  • Enzyme Substrates
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide DonorsEnzyme Substrates
  • Nitric Oxide Synthase/NO Donor
  • Nitric Oxide and Cell Stress
  • Nitric Oxide Metabolism
  • Substrates by Enzyme